Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
11
SaaS
Science as a Service
Abner Huang
<abnercyh@cs.nthu.edu.tw>
CSBB Lab., NTHU
Dec. 14, 2011
Figure from GEN News High...
22
Science is different
3
Science as a service
4
6
Evolution of Biomedical
researchers
7
Nature: Milestones in DNA
1977
DNA sequencing
1990
BLAST
2002
UCSC Genome browser
2004
Ensembl
Figure from http://www.na...
8
The Trend of NGS
BRIEFINGS IN BIOINFORMATICS. VOL 11. NO 5. 484 ^ 498
9
Illumina's Certified Service
Providers
www.illumina.com/services/cspro.ilmn
10
Personal Genome and
Clinical Business
11
http://news.sciencemag.org/scienceinsider/2010/06/uk-to-sequence-10000-genomes.html
12
NHGRI’s New Sequencing Projects
• Genome Sequencing
– Near $85 million in the first year
• Mendelian Disorders
– $12 mi...
13
The Trend of NGS
ivory.idyll.org/permanent/lstein-ngs-capacity.png
1414
Challenges for Biomedical
researchers
15
Solve It Using Cloud
Computing
http://genomebiology.com/2010/11/5/207
16
``Cloud Computing’’ in PubMed
17
Biomedical Institutes hug cloud
computing
• J. Craig Venter Institute released JCVI
CLOUD BIO-LINUX
• IBM eX5 Improves ...
18
Startup Companies
19
Galaxy Cloud
21
http://www.biomedcentral.com/1471-2105/11/S12/S4
Galaxy Cloud
22
Parallel Algorithms Spectrum
23
CloudBurst
24
25
RNAseq Unified Mapper (RUM)
26
Myrna
27
28
Contrail
29
What’s Next?
• Alternative expression
• Allelic expression
• Structural variation
• Epigenomics
• Metagenomics
• Biologica...
32
NGS economics
Biomedical
Researcher
Instrument
vendors
Sequencing
outsourcing
Analysis
outsourcing
Consultants
33
NGS economics
Biomedical
Researcher
Instrument
vendors
Sequencing
outsourcing
Analysis
outsourcing
ODM
Consultants
34
NGS economics on clouds
Biomedical
Researcher
Instrument
vendors
Sequencing
outsourcing
Analysis
outsourcing
Fabless
ODM
C...
Voila! RNA-Seq Data Analysis
36
38
IaaS
Infrastructure as a Service
PaaS
Platform as a Service
SaaS
Software as a Service
Cloud Service Models for Scienti...
39
Eating your own dog food
40
41
Science as a service
Service as a science
42
Loose coupled interdisciplinary
43
Service science and cloud
computing
• HPC on cloud computing of NGS
• Data Transfer Bottlenecks
• Streaming Computing
• Co...
THANK YOU
45
Upcoming SlideShare
Loading in …5
×

94

Share

Download to read offline

SaaS: Science as a Service

Download to read offline

SaaS Science as a Service

Related Books

Free with a 30 day trial from Scribd

See all

SaaS: Science as a Service

  1. 1. 11 SaaS Science as a Service Abner Huang <abnercyh@cs.nthu.edu.tw> CSBB Lab., NTHU Dec. 14, 2011 Figure from GEN News Highlights: Jul 2, 2010
  2. 2. 22
  3. 3. Science is different 3
  4. 4. Science as a service 4
  5. 5. 6 Evolution of Biomedical researchers
  6. 6. 7 Nature: Milestones in DNA 1977 DNA sequencing 1990 BLAST 2002 UCSC Genome browser 2004 Ensembl Figure from http://www.nature.com/milestones/miledna/timeline.html
  7. 7. 8 The Trend of NGS BRIEFINGS IN BIOINFORMATICS. VOL 11. NO 5. 484 ^ 498
  8. 8. 9 Illumina's Certified Service Providers www.illumina.com/services/cspro.ilmn
  9. 9. 10 Personal Genome and Clinical Business
  10. 10. 11 http://news.sciencemag.org/scienceinsider/2010/06/uk-to-sequence-10000-genomes.html
  11. 11. 12 NHGRI’s New Sequencing Projects • Genome Sequencing – Near $85 million in the first year • Mendelian Disorders – $12 million per year • Clinical Exploration – $10.3 million per year • Informatics Tools – $20 million for four years 12 http://www.genome.gov/27546261
  12. 12. 13 The Trend of NGS ivory.idyll.org/permanent/lstein-ngs-capacity.png
  13. 13. 1414 Challenges for Biomedical researchers
  14. 14. 15 Solve It Using Cloud Computing http://genomebiology.com/2010/11/5/207
  15. 15. 16 ``Cloud Computing’’ in PubMed
  16. 16. 17 Biomedical Institutes hug cloud computing • J. Craig Venter Institute released JCVI CLOUD BIO-LINUX • IBM eX5 Improves Next Generation Sequencing for Sanger Institute • ISB made Trans-Proteomic Pipeline (TPP) on clouds.
  17. 17. 18 Startup Companies
  18. 18. 19
  19. 19. Galaxy Cloud 21 http://www.biomedcentral.com/1471-2105/11/S12/S4
  20. 20. Galaxy Cloud 22
  21. 21. Parallel Algorithms Spectrum 23
  22. 22. CloudBurst 24
  23. 23. 25
  24. 24. RNAseq Unified Mapper (RUM) 26
  25. 25. Myrna 27
  26. 26. 28
  27. 27. Contrail 29
  28. 28. What’s Next? • Alternative expression • Allelic expression • Structural variation • Epigenomics • Metagenomics • Biological data/text mining • Hapotype/Hapomap • K thousand genomes 30
  29. 29. 32
  30. 30. NGS economics Biomedical Researcher Instrument vendors Sequencing outsourcing Analysis outsourcing Consultants 33
  31. 31. NGS economics Biomedical Researcher Instrument vendors Sequencing outsourcing Analysis outsourcing ODM Consultants 34
  32. 32. NGS economics on clouds Biomedical Researcher Instrument vendors Sequencing outsourcing Analysis outsourcing Fabless ODM Consultants 35 2 1 3 4
  33. 33. Voila! RNA-Seq Data Analysis 36
  34. 34. 38 IaaS Infrastructure as a Service PaaS Platform as a Service SaaS Software as a Service Cloud Service Models for Scientists www.spoutingshite.com/wp-content/uploads/2008/12/saas_and_cloud_computing.ppt
  35. 35. 39 Eating your own dog food
  36. 36. 40
  37. 37. 41
  38. 38. Science as a service Service as a science 42
  39. 39. Loose coupled interdisciplinary 43
  40. 40. Service science and cloud computing • HPC on cloud computing of NGS • Data Transfer Bottlenecks • Streaming Computing • Cost of Cloud Storage • Community Cloud Developing • App. Exchange of bioinformatics 44
  41. 41. THANK YOU 45
  • JudithSalinas6

    Jul. 29, 2021
  • drrichardselden

    Mar. 3, 2021
  • ShivKumar964

    Feb. 8, 2021
  • MichelleSantiago46

    Jan. 19, 2020
  • VishalChavan86

    Sep. 25, 2019
  • larrymayer

    Oct. 22, 2018
  • marykattah78

    Aug. 28, 2018
  • Lisa_Landman

    Jul. 5, 2018
  • madhukumari62

    Feb. 21, 2018
  • michele-carbone

    Jul. 11, 2017
  • djalitiger

    Jun. 17, 2017
  • shashk

    May. 1, 2017
  • JohnGoodwin10

    Apr. 30, 2017
  • salimataibi

    Apr. 29, 2017
  • karimdossani

    Mar. 1, 2017
  • Jodongoo

    Feb. 7, 2017
  • ElieHirschfeld11

    Jan. 18, 2017
  • RussellUrie

    Nov. 29, 2016
  • PalashKumarSeal

    Nov. 5, 2016
  • almasnaqvi1

    Sep. 22, 2016

SaaS Science as a Service

Views

Total views

8,886

On Slideshare

0

From embeds

0

Number of embeds

31

Actions

Downloads

206

Shares

0

Comments

0

Likes

94

×