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Alkaloid Chemical
Class
Occurrence Uses Chemical test
Ephedrine
Phenyl
alkylamine
Ephedra sinica
F. Ephedraceae
Relieve asthma and hay
fever.
Nasal decongestant
Dragendorrf’s reagent
 long plates shape
crystals
Cathine
Phenyl
alkylamine
Catha edulis
F. Celastraceae
CNS stimulant Mayer’s reagent 
white ppt
Mescaline
Phenyl
alkylamine
Cactus lophophora
F. Cactaceae
Hallucinogenic and
psychoactive
Marqui's reagent 
orange color
Capsaicin
Phenyl
alkylamine
Capsicum annuum
F. Solanaceae
Counter-irritant to
relief rheumatism and
lumbago
Alcoholic solution +
FeCl3
Green color
Colchicine
Tropolone Colchicum
autumnale F.
Liliaceae
Treatment of gout Conc. HNO3  dirty
green color 
brown yellow.
Nicotine
Pyridine Nicotiana tabacum
F. Solanaceae
Insecticide
Used commercially to
produce Nicotinic acid
or Niacin (Vitamin B3)
Aqueous solution +
Vanillin/ HCl  Red
color
Piperine
Piperidine Piper nigrum
F. Piperaceae
Condiment.
Tonic and rubefacient
H2SO4  red color
Coniine
Piperidine Conium
maculatum F.
Umbelliferae
local analgesic in
treatment of
hemorrhoids and anal
fissures
Sodium nitroprusside
red color blue or
violet
Lobeline
Piperidine Lobelia inflata
F. Campanulaceae
Respiratory stimulant.
Expectorant.
Relieve asthma.
Marqui`s reagent 
red violet color
Pyridone Ricinus communis
F. Euphorbiaceae
Toxic alkaloid KMnO4 decolorize
the color
N
OMe
C
O
CH3
N
Ricinine
pyrrolizidine Heliotropium
europaeum
(Boraginaceae)
Anticancer
used for snakebite and
scorpion stings
+Ehrlich R. gives blue
to purple color
pyrrolizidine Senecio vulgaris.
(Compositae)
Controls pulmonary
hemorrhage
+Ehrlich R. gives blue
to purple color
Indicine N-oxide
pyrrolizidine Heliotropium
indicum
(Boraginaceae)
In early clinical studies
the possibility of using it
for the treatment of
leukemia
+Ehrlich R. gives blue
to purple color
Atropine
Tropane Atropa belladonna
F. Solanaceae
Anti-cholinergic,
mydriatic, antispasmodic
Preanesthetic, antidote
for organophosphorus
poisoning
Vitali-Morin’s
Testpurple color
Hyoscyamine
Tropane Hyoscyamus
muticus
F. Solanaceae
Antispasmodic
Anti-cholinergic
Vitali-Morin’s
Testred color
Hyoscine
Tropane Hyoscyamus
muticus
F. Solanaceae
Antispasmodic
Sedative and CNS
depressant.
Vitali-Morin’s
Testred color
Cocaine
Tropane Erythroxylum coca
F.
Erythroxylaceae
local anaesthetic
CNS stimulant effect,
followed by a hypnotic
effect.
+p-dimethylamino
benzaldehyde (▲) red
color
Hygrine
Pyrrolidine Erythroxylum coca
F.
Erythroxylaceae
Sedative
Hypnotic
It gives characteristic
crystals with gold
chloride and platinic
chloride
Quinine
Quinoline Cinchona
succirubra
F. Rubiaceae
Anti-malarial Thalleioquin test
 emerald green color
Quinidine
Quinoline Cinchona
succirubra
F. Rubiaceae
Anti- arrhythmic Thalleioquin test
 emerald green color
Emetine
Isoquinoline Cephaelis
ipecacuanha
F. Rubiaceae
Expectorant and emetic
Amoebic dysentery
treatment
Ipecacuanha alkaloids
in HCl + Ca-
hypochlorite 
Orange color
d- Tubocurarine
Isoquinoline Chondrodendron
tomentosum
F.Menispermaceae
Skeletal muscle relaxant Saturated aqueous
solution + FeCl3 
Green color
Morphine
Phenanthrene Papaver
somniferum
F. Papaveraceae
Powerful analgesic and
narcotic
+ FeCl3  blue color
Codeine
Phenanthrene Papaver
somniferum
F. Papaveraceae
Anti-tussive
Non-addictive medium
analgesic
+ FeCl3 + Conc H2SO4
(▲) Blue color +
HNO3 Red colour
Eserine
Indol Physostigma
venenosum
F. Leguminosae
A myotic drug, it has a
cholinergic effect and
stimulates gland
secretion
Eserine blue test
Strychnine
Indol Strychnos nux
vomica
F. Lganiaceae
Rodenticide + HNO3 Yellow color
Brucine
Indol Strychnos nux
vomica
F. Lganiaceae
CNS stimulant + HNO3 orange red
color (evap. + SnCl2)
violet colour
Ergometrine
Indol Claviceps purpurea
F. Clavicipitaceae
Oxytocic Van-Urk’s test
Ergotamine
Indol Claviceps purpurea
F. Clavicipitaceae
Migraine Van-Urk’s test
Vincristine
Indol Catharanthus
roseus
F. Apocyanaceae
Leukemia
HPLC
Vinblastine
Indol Catharanthus
roseus
F. Apocyanaceae
Hodgkin’s disease
HPLC
Yohimbine
Indol
β-Carboline
Coryanthe
yohimba,
F. Rubiaceae
Aphrodisiac + conc. H2SO4 + crystals
of K2Cr2O7  violet
streaks  blue green
Reserpine
Indol
β-Carboline
Rauwolfia
serpentina
F. Apocynaceae
Antihypertensives +p-dimethylamino
benzaldehyde (Glacial
acetic acidH2SO4)
green color red in
acid
Pilocarpine
Imidazol Pilocarpus
jaborandi, F.
Rutaceae
Miotic for treatment of
glaucoma
cholinergic agent
Helch’s test
Caffeine
Purine Camellia sinensis
F. Theaceae
CNS stimulant
Analgesic
Murexide test
Theophylline
Purine Theobroma cacao
F. Sterculiaceae
Diuretic
Respiratory stimulant
Murexide test
Theobromine
Purine Theobroma cacao
F. Sterculiaceae
Little stimulant action,
more diuretic activity
than Caffeine
Murexide test
Solanine
Steroidal Solanum
tuberosum
F. solanaceae
Starting material for
synthesis of sexual
hormones and
corticosteroids.
Mayer’s reagent 
white ppt
Solasonine
Steroidal Solanum
tuberosum
F. solanaceae
Starting material for
synthesis of sexual
hormones and
corticosteroids.
Mayer’s reagent 
white ppt
Taxol
Diterpene Taxus brevifolia,
F. taxaceae
Ovarian, breast and lung
cancer
HPLC

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Table of alkaloids

  • 1. Alkaloid Chemical Class Occurrence Uses Chemical test Ephedrine Phenyl alkylamine Ephedra sinica F. Ephedraceae Relieve asthma and hay fever. Nasal decongestant Dragendorrf’s reagent  long plates shape crystals Cathine Phenyl alkylamine Catha edulis F. Celastraceae CNS stimulant Mayer’s reagent  white ppt Mescaline Phenyl alkylamine Cactus lophophora F. Cactaceae Hallucinogenic and psychoactive Marqui's reagent  orange color Capsaicin Phenyl alkylamine Capsicum annuum F. Solanaceae Counter-irritant to relief rheumatism and lumbago Alcoholic solution + FeCl3 Green color Colchicine Tropolone Colchicum autumnale F. Liliaceae Treatment of gout Conc. HNO3  dirty green color  brown yellow. Nicotine Pyridine Nicotiana tabacum F. Solanaceae Insecticide Used commercially to produce Nicotinic acid or Niacin (Vitamin B3) Aqueous solution + Vanillin/ HCl  Red color Piperine Piperidine Piper nigrum F. Piperaceae Condiment. Tonic and rubefacient H2SO4  red color Coniine Piperidine Conium maculatum F. Umbelliferae local analgesic in treatment of hemorrhoids and anal fissures Sodium nitroprusside red color blue or violet Lobeline Piperidine Lobelia inflata F. Campanulaceae Respiratory stimulant. Expectorant. Relieve asthma. Marqui`s reagent  red violet color Pyridone Ricinus communis F. Euphorbiaceae Toxic alkaloid KMnO4 decolorize the color N OMe C O CH3 N Ricinine
  • 2. pyrrolizidine Heliotropium europaeum (Boraginaceae) Anticancer used for snakebite and scorpion stings +Ehrlich R. gives blue to purple color pyrrolizidine Senecio vulgaris. (Compositae) Controls pulmonary hemorrhage +Ehrlich R. gives blue to purple color Indicine N-oxide pyrrolizidine Heliotropium indicum (Boraginaceae) In early clinical studies the possibility of using it for the treatment of leukemia +Ehrlich R. gives blue to purple color Atropine Tropane Atropa belladonna F. Solanaceae Anti-cholinergic, mydriatic, antispasmodic Preanesthetic, antidote for organophosphorus poisoning Vitali-Morin’s Testpurple color Hyoscyamine Tropane Hyoscyamus muticus F. Solanaceae Antispasmodic Anti-cholinergic Vitali-Morin’s Testred color Hyoscine Tropane Hyoscyamus muticus F. Solanaceae Antispasmodic Sedative and CNS depressant. Vitali-Morin’s Testred color Cocaine Tropane Erythroxylum coca F. Erythroxylaceae local anaesthetic CNS stimulant effect, followed by a hypnotic effect. +p-dimethylamino benzaldehyde (▲) red color Hygrine Pyrrolidine Erythroxylum coca F. Erythroxylaceae Sedative Hypnotic It gives characteristic crystals with gold chloride and platinic chloride Quinine Quinoline Cinchona succirubra F. Rubiaceae Anti-malarial Thalleioquin test  emerald green color
  • 3. Quinidine Quinoline Cinchona succirubra F. Rubiaceae Anti- arrhythmic Thalleioquin test  emerald green color Emetine Isoquinoline Cephaelis ipecacuanha F. Rubiaceae Expectorant and emetic Amoebic dysentery treatment Ipecacuanha alkaloids in HCl + Ca- hypochlorite  Orange color d- Tubocurarine Isoquinoline Chondrodendron tomentosum F.Menispermaceae Skeletal muscle relaxant Saturated aqueous solution + FeCl3  Green color Morphine Phenanthrene Papaver somniferum F. Papaveraceae Powerful analgesic and narcotic + FeCl3  blue color Codeine Phenanthrene Papaver somniferum F. Papaveraceae Anti-tussive Non-addictive medium analgesic + FeCl3 + Conc H2SO4 (▲) Blue color + HNO3 Red colour Eserine Indol Physostigma venenosum F. Leguminosae A myotic drug, it has a cholinergic effect and stimulates gland secretion Eserine blue test Strychnine Indol Strychnos nux vomica F. Lganiaceae Rodenticide + HNO3 Yellow color Brucine Indol Strychnos nux vomica F. Lganiaceae CNS stimulant + HNO3 orange red color (evap. + SnCl2) violet colour Ergometrine Indol Claviceps purpurea F. Clavicipitaceae Oxytocic Van-Urk’s test
  • 4. Ergotamine Indol Claviceps purpurea F. Clavicipitaceae Migraine Van-Urk’s test Vincristine Indol Catharanthus roseus F. Apocyanaceae Leukemia HPLC Vinblastine Indol Catharanthus roseus F. Apocyanaceae Hodgkin’s disease HPLC Yohimbine Indol β-Carboline Coryanthe yohimba, F. Rubiaceae Aphrodisiac + conc. H2SO4 + crystals of K2Cr2O7  violet streaks  blue green Reserpine Indol β-Carboline Rauwolfia serpentina F. Apocynaceae Antihypertensives +p-dimethylamino benzaldehyde (Glacial acetic acidH2SO4) green color red in acid Pilocarpine Imidazol Pilocarpus jaborandi, F. Rutaceae Miotic for treatment of glaucoma cholinergic agent Helch’s test Caffeine Purine Camellia sinensis F. Theaceae CNS stimulant Analgesic Murexide test Theophylline Purine Theobroma cacao F. Sterculiaceae Diuretic Respiratory stimulant Murexide test Theobromine Purine Theobroma cacao F. Sterculiaceae Little stimulant action, more diuretic activity than Caffeine Murexide test
  • 5. Solanine Steroidal Solanum tuberosum F. solanaceae Starting material for synthesis of sexual hormones and corticosteroids. Mayer’s reagent  white ppt Solasonine Steroidal Solanum tuberosum F. solanaceae Starting material for synthesis of sexual hormones and corticosteroids. Mayer’s reagent  white ppt Taxol Diterpene Taxus brevifolia, F. taxaceae Ovarian, breast and lung cancer HPLC