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Neurological
Examination of an
Infant
Amr Hasan, MD,FEBN
Associate Professor of Neurology -
Cairo University
•Neurological examination in pediatrics varies
according to age e.g. : the approach to neonates
will vary from that of children.
•Observation is key to diagnosis since physical
signs are usually less obvious than in adults.
•Talk to the parents.
•A child older than 3 to 5 years might provide
information that not only is valuable, but also may be
more reliable than that related by his or her parents.
•Do not ask leading questions.
•The physician also must be responsive to the
youngster's mood and cease taking a history as soon as
fatigue or restlessness becomes evident.
•In a younger child or one with a limited attention span,
the salient points of the history are best secured at the
onset of the evaluation.
•Allow older children play as you observe.
•This may require that you have some toys.
•Communicate with the children.
•A review of the perinatal events is always in
order.
•Feeding history.
•A history of abnormal sleeping habits.
•Major childhood illnesses
•Immunizations
•Injuries
•The family history
•The toddler is more difficult to examine. The toddler is
best approached by seating the child in the mother's or
father's lap and talking to the child.
•Because toddlers are fearful of strangers, the physician
must first observe the youngster and defer touching him
or her until some degree of rapport has been established.
•Offering a small, interesting toy may bridge the
gap.
•Once frightened, most toddlers are difficult to
reassure and are lost for the remainder of the
examination.
•The child's height, weight, blood pressure, and head
circumference must always be measured and recorded.
•The youngster should be undressed by the parents,
with the physician absent.
•The physician should note the general appearance of
the child.
• Note facial configuration,presence of any dysmorphic
feature & Cutaneous lesions.
•The condition of the teeth provides information
about antenatal defects or kernicterus.
•The location of the hair whorl and the
appearance of the palmar creases should always
be noted.
•The quality of the scalp hair, eyebrows, and nails
also should be taken into account.
•It is important to inspect the midline of the neck,
back, and pilonidal area for any defects,
particularly for small dimples that might indicate
the presence of a dermoid sinus tract.
•Examination of chest, heart, and abdomen and
palpation of the femoral pulses should always be
part of the general physical examination.
•Finally, the presence of an unusual body odor
may offer a clue to a metabolic disorder.
The neurologic examination of an infant younger
than 1 year of age can be divided into three
parts:
1. Evaluation of posture and tone
2. Evaluation of primitive reflexes
3. Age invariable tests.
The neurologic examination of an infant younger
than 1 year of age can be divided into three
parts:
1. Evaluation of posture and tone
2. Evaluation of primitive reflexes
3. Age invariable tests.
1. Evaluation of posture and tone
Evaluation of posture and muscle tone is a
fundamental part of the neurologic
examination of infants. It involves
examination of:
A. Resting Posture
B. Passive Tone
C. Active Tone
1.Evaluation of posture and tone:
A. Resting Posture:
Posture is appreciated by inspecting the undressed
 During the first few months of life, normal
hypertonia of the flexors of the elbows, hips,
and knees occurs.
 The hypertonia decreases markedly during the
third month of life, first in the upper
extremities and later in the lower extremities.
1.Evaluation of posture and tone:
A. Resting Posture:
 At the same time, tone in neck and trunk
increases.
 Between 8 and 12 months of age, a further
decrease occurs in the flexor tone of the
extremities together with increased extensor
tone .
1. Evaluation of posture and tone
B. Passive tone
 Is accomplished by determining the resistance
to passive movements of the various joints
with the infant awake and not crying.
 Because limb tone is influenced by tonic neck
reflexes, it is important to keep the child's head
straight during this part of the examination.
1. Evaluation of posture and tone
B. Passive tone
 Passive flapping of the hands and the feet
provides a simple means of ascertaining
muscle tone.
 In the upper extremity, the scarf sign is a
valuable maneuver.
 In the lower extremity, the fall-away response
serves a similar purpose.
1. Evaluation of posture and tone:
C. Active tone:
 The traction response is an excellent means of
ascertaining active tone
 The examiner, who should be sitting down
and facing the child, places his or her thumbs
in the infant's palms and fingers around the
wrists and gently pulls the infant from the
supine position.
1. Evaluation of posture and tone:
C. Active tone:
 In the healthy infant younger than 3 months of
age, the palmar grasp reflex becomes operative,
the elbows tend to flex, and the flexor muscles
of the neck are stimulated to raise the head so
that even in the full-term neonate the extensor
and flexor tone are balanced and the head is
maintained briefly in the axis of the trunk.
The neurologic examination of an infant younger
than 1 year of age can be divided into three
parts:
1. Evaluation of posture and tone
2. Evaluation of primitive reflexes
3. Age invariable tests.
The neurologic examination of an infant younger
than 1 year of age can be divided into three
parts:
1. Evaluation of posture and tone
2. Evaluation of primitive reflexes
3. Age invariable tests.
2. Evaluation of primitive reflexes:
 The evaluation of primitive reflexes is an
integral part of the neurologic examination of
the infant.
 This disappearance should not be construed as
meaning that they are actually lost, for a reflex
once acquired in the course of development is
retained permanently.
2. Evaluation of primitive reflexes:
 Rather, these reflexes, which develop during
intrauterine life, are gradually suppressed as
the higher cortical centers become functional.
2. Evaluation of primitive reflexes:
A. Segmental Medullary Reflexes: A number of segmental medullary reflexes
become functional during the last trimester of gestation. They include
(a) respiratory activity.
(b) cardiovascular reflexes.
(c) coughing reflex mediated by the vagus nerve.
(d) sneezing reflex evoked by afferent fibers of the trigeminal nerve.
(e)swallowing reflex mediated by the trigeminal and glossopharyngeal
nerves.
(f) sucking reflex.
2. Evaluation of primitive reflexes:
B. Flexion Reflex:
 This response is elicited by the unpleasant stimulation
of the skin of the lower extremity, most consistently the
dorsum of the foot, and consists of dorsiflexion of the
great toe and flexion of the ankle, knee, and hip.
2. Evaluation of primitive reflexes:
B. Flexion Reflex
 This reflex has been elicited in immature fetuses and
can persist as a fragment, the extensor plantar
response, for the first 2 years of life. It is seen also in
infants whose higher cortical centers have been
profoundly damaged.
2. Evaluation of primitive reflexes:
C. Moro Reflex
The Moro reflex is best elicited by a sudden
dropping of the baby's head in relation to its
trunk. Moro, however, elicited this reflex by
hitting the infant's pillow with both hands.
2. Evaluation of primitive reflexes:
C. Moro Reflex
 The infant opens the hands, extends and abducts
the upper extremities, and then draws them
together. The reflex first appears between 28 and
32 weeks' gestation and is present in all newborns.
 It fades out between 3 to 5 months of age.

2. Evaluation of primitive reflexes:
C. Moro Reflex
Its persistence beyond 6 months of age or its
absence or diminution during the first few
weeks of life indicates neurologic dysfunction.
2. Evaluation of primitive reflexes:
D. Tonic Neck Response
The tonic neck response is obtained by rotating
the infant's head to the side while maintaining
the chest in a flat position.
A positive response is extension of the arm and
leg on the side toward which the face is rotated
and flexion of the limbs on the opposite side .
2. Evaluation of primitive reflexes:
D. Tonic Neck Response
Inconstant tonic neck responses can be elicited
for as long as 6 to 7 months of age and can even
be momentarily present during sleep in the
healthy 2- to 3-year-old child .
2. Evaluation of primitive reflexes:
E.Righting Reflex
 With the infant in the supine position, the
examiner turns the head to one side. The healthy
infant rotates the shoulder in the same direction,
followed by the trunk, and finally the pelvis.
 An obligate neck-righting reflex in which the
shoulders, trunk, and pelvis rotate
simultaneously and in which the infant can be
rolled over and over like a log is always
abnormal.
2. Evaluation of primitive reflexes:
F. Palmar and Plantar Grasp Reflexes
 The palmar and plantar grasp reflexes are
elicited by pressure on the palm or sole.
 Generally, the plantar grasp reflex is weaker
than the palmar reflex.
2. Evaluation of primitive reflexes:
F. Palmar and Plantar Grasp Reflexes:
 The palmar grasp reflex appears at 28 weeks'
gestation, is well established by 32 weeks, and
becomes weak and inconsistent between 2 and 3
months of age, when it is covered up by
voluntary activity.
2. Evaluation of primitive reflexes:
F. Palmar and Plantar Grasp Reflexes:
 Absence of the reflex before 2 or 3 months of
age, persistence beyond that age, or a consistent
asymmetry is abnormal.
 The reappearance of the grasp reflex in frontal
lobe lesions reflects the unopposed parietal lobe
activity.
2. Evaluation of primitive reflexes:
G.Vertical Suspension
 The examiner suspends the child with his or
her hand under its axillae and notes the
position of the lower extremities.
 Marked extension or scissoring is an indication
of spasticity.
2. Evaluation of primitive reflexes:
H.Landau Reflex
 To elicit the Landau response, the examiner lifts
the infant with one hand under the trunk, face
downward.
 Normally, a reflex extension of the vertebral
column occurs, causing the newborn infant to lift
the head to slightly below the horizontal, which
results in a slightly convex upward curvature of
the spine. With hypotonia, the infant's body tends
to collapse into an inverted U shape.
2. Evaluation of primitive reflexes:
H.Landau Reflex
 With hypotonia, the infant's body tends to
collapse into an inverted U shape.
2. Evaluation of primitive reflexes:
I.Buttress Response
 To elicit the buttress response, the examiner
places the infant in the sitting position and
displaces the center of gravity with a gentle
push on one shoulder.
2. Evaluation of primitive reflexes:
I.Buttress Response
 The infant extends the contralateral arm and
spreads the fingers.
 The reflex normally appears at approximately 5
months of age. Delay in its appearance and
asymmetries are significant.
2. Evaluation of primitive reflexes:
J.Parachute Response
 The parachute reflex is tested with the child
suspended horizontally about the waist, face
down.
 The infant is then suddenly projected toward
the floor, with a consequent extension of the
arms and spreading of the fingers.
2. Evaluation of primitive reflexes:
J.Parachute Response:
 Between 4 and 9 months of age, this reflex
depends on visual and vestibular sensory input
and is proportional to the size of the optic
stimulus pattern on the floor.
2. Evaluation of primitive reflexes:
K.Reflex Placing and Stepping Responses
 Reflex placing is elicited by stimulating the
dorsum of the foot against the edge of the
examining table.
 Reflex stepping, which is at least partly a
function of the flexion response, is present in
the healthy newborn when the infant is
supported in the standing position; it
disappears in the fourth or fifth month of life.
2. Evaluation of primitive reflexes:
L.Reflex Suck, Root
 exam video06 Func_int-DevRfx.mpg
The neurologic examination of an infant younger
than 1 year of age can be divided into three
parts:
1. Evaluation of posture and tone
2. Evaluation of primitive reflexes
3. Age invariable tests.
The neurologic examination of an infant younger
than 1 year of age can be divided into three
parts:
1. Evaluation of posture and tone
2. Evaluation of primitive reflexes
3. Age invariable tests.
3.Age-Invariable Tests
The last part of the neurologic examination
involves tests similar to those performed in
older children or adults, such as the funduscopic
examination and the deep tendon reflexes.
•In addition to the standard instruments used in
neurologic examination, the following have
been found useful:
•a tennis ball
•few small toys
•a bell
•some object that attracts the child's attention
(e.g., a pinwheel).
•In most intellectually healthy school-aged
children, the general physical and neurologic
examinations can be performed in the same
manner as for adults
•Except that fundus examination, corneal and gag
reflexes and sensory testing, should be postponed
until the end.
Olfactory Nerve
Olfactory sensation as transmitted by the
olfactory nerve is not functional in the newborn,
but is present by 5 to 7 months of age.
Optic Nerve
•Fundus examination
•Visual acquity
•Visual field
Optic Nerve
•In infants, the optic disc is normally pale and gray,
an appearance similar to optic atrophy in later life.
•Premature and newborn infants have
incompletely developed uveal pigment, resulting
in a pale appearance of the fundus and a clear
view of the choroidal blood vessels.
Optic Nerve
•Retinal hemorrhages are seen in one-third of
vaginally delivered newborns.
•They are usually small and multiple, and their
presence does not necessarily indicate intracranial
bleeding.
Optic Nerve
Visual acuity can be tested in the older child by
standard means.
In the toddler, an approximation can be
obtained by observing him or her at play or by
offering objects of varying sizes.
Optic Nerve
Optokinetic nystagmus can be elicited by
rotating a striped drum or by drawing a strip of
cloth with black and white squares in front of
the child's eyes.
The presence of optokinetic nystagmus confirms
cortical vision; its absence, however, is
inconclusive.
Optic Nerve
The blink reflex, closure of the eyelids when an
object is suddenly moved toward the eyes, is
often used to determine the presence of
functional vision in small infants.
Optic Nerve
The macular light reflex is absent until
approximately 4 months of age.
It is present in approximately one-half of
healthy 5-month-old infants and should be
present in all infants by 1 year of age
Optic Nerve
The visual fields can be assessed in toddlers and
in infants younger than 12 months of age.
The baby is placed in the mother's lap and the
physician is seated in front of them, using a
small toy to attract the baby's attention.
Neurologic examination of the
infant
Optic Nerve
An assistant standing in back of the infant
brings another object into the field of vision, and
the point at which the infant's eyes or head turns
toward the object is noted.
Neurologic examination of the
infant
Oculomotor, Trochlear, and Abducens Nerves:
Extraocular Movements
The physician notes the position of the eyes at rest.
Noting the points of reflection of a flashlight assists
in detecting a nonparallel alignment of the eyes.
The size of the pupils, their reactivity to light, and
accommodation and convergence are noted.
Neurologic examination of
the infant
Oculomotor, Trochlear, and Abducens Nerves:
Extraocular Movements
A slight degree of anisocoria is not unusual,
particularly in infants and small children.
Fatigue-induced anisocoria also has been noted
to be transmitted as an autosomal dominant
trait
Neurologic examination of
the infant
Oculomotor, Trochlear, and Abducens Nerves:
Extraocular Movements
Following movements are complete in all
directions by approximately 4 months of age,
and acoustically elicited eye movements appear
at 5 months of age .
Depth perception using solely binocular cues
appears by 24 months of age along with stable
binocular alignment and optokinetic nystagmus.
Neurologic examination of the
infant
Trigeminal Nerve
The corneal reflex tests the intactness of the
ophthalmic branch of the trigeminal nerve.
A defect should be suspected when spontaneous
blinking on one side is slower and less complete.
The frequency of blinking increases with
maturation and decreases in toxic illnesses.
Facial Nerve
•Impaired motor function is indicated by facial
asymmetry.
•The McCarthy reflex, ipsilateral blinking
produced by tapping the supraorbital region, is
diminished or absent in lower motor neuron
facial weakness.
•
Neurologic examination of the
infant
Facial Nerve
•Palpebral reflex, bilateral blinking induced by
tapping the root of the nose, it can be
exaggerated by upper motor neuron lesions.
•In hemiparesis or peripheral facial nerve
weakness, the contraction of the platysma
muscle is less vigorous on the affected side, This
sign also carries Babinski's name.
Neurologic examination of the
infant
Facial Nerve
An isolated weakness of the depressor of the
corner of the mouth (depressor anguli oris) is
relatively common in children.
It results in a failure to pull the affected side of
the mouth backward and downward when
crying.
Neurologic examination of the
infant
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Cochlear Nerve
•Hearing can be tested in the younger child by
observing the child's response to a bell.
•Small infants become alert to sound; the ability
to turn the eyes to the direction of the sound
becomes evident by 7 to 8 weeks of age, and
turning with eyes and head appears by
approximately 3 to 4 months of age.
Neurologic examination of the
infant
Cochlear Nerve
•Hearing is tested in older children by asking
them to repeat a whispered word or number.
•For more accurate evaluation of hearing,
audiometry or brainstem auditory-evoked
potentials are necessary.
Neurologic examination of the
infant
Vestibular Nerve
•Vestibular function can be assessed easily in
infants or small children by holding the youngster
vertically so he or she is facing the examiner, then
turning the child several times in a full circle.
•Clockwise and counterclockwise rotations are
performed. The direction and amplitude of the
quick and slow movements of the eye are noted.
Neurologic examination of the
infant
Vestibular Nerve
•The healthy infant demonstrates full deviation of
the eyes in the direction that he or she is being
rotated with the quick phase of the nystagmus
backward. When rotation ceases, these directions
are reversed.
Neurologic examination of the
infant
Glossopharyngeal and Vagus Nerves
•The gag reflex tests the afferent and efferent
portions of the vagus.
•This reflex is absent in approximately one-third
of healthy individuals.
•Testing taste over the posterior part of the
tongue is extremely difficult and, according to
some opinions, generally not worth the effort.
Neurologic examination of the
infant
Spinal Accessory Nerve
Testing the sternocleidomastoid muscle can be
done readily by having the child rotate his or
her head against resistance.
Neurologic examination of the
infant
Hypoglossal Nerve
•The position of the tongue at rest should be
noted with the mouth open.
•The tongue deviates toward the paretic side.
•Fasciculations are seen as small depressions
that appear and disappear quickly at irregular
intervals.
Neurologic examination of the
infant
Hypoglossal Nerve
•They are most readily distinguished on the
underside of the tongue.
•Their presence cannot be determined with any
reliability if the youngster is crying.
Neurologic examination of the
infant
Motor system examination:
•Similarly, the walking and running gaits can be
seen by playing with the youngster and asking
him or her to retrieve a ball and run outside of
the examining room.
•In the course of such an informal examination,
sufficient information can be obtained so that
the formal testing of muscle strength is only
confirmatory.
Neurologic examination of the
infant
In toddlers or infants, inequalities of tone have
been found to provide more information than
assessment of muscle strength or reflexes.
A sensitive test for weakness of the upper
extremities is the pronator sign, in which the
hand on the hypotonic side hyperpronates to
palm outward as the arms are raised over the
head. Additionally, the elbow may flex .
Neurologic examination of the
infant
In the lower extremities, weakness of the flexors
of the knee can readily be demonstrated by
having the child lie prone and asking the child
to maintain his or her legs in flexion at right
angles at the knee.
An unsustained ankle clonus is common in the
healthy neonate.
Neurologic examination of the
infant
Coordination
Coordination can be tested by applying specific
tests for cerebellar function, such as having the
youngster reach for and manipulate toys.
The ability to perform rapidly alternating
movements can be assessed by having the child
repeatedly pat the examiner's hand, or by
having the child perform rapid pronation and
supination of the hands.
Neurologic examination of the
infant
Coordination
The heel-to-shin test is not an easy task for many
youngsters to comprehend, and performance
must be interpreted with regard to the child's
age and level of intelligence.
Neurologic examination of the
infant
 A proper sensory examination is difficult at
any age, and almost impossible in an infant or
toddler.
 In infants or toddlers, abnormalities in skin
temperature or in the amount of perspiration
indicate the level of sensory deficit.
Neurologic examination of the
infant
 The ulnar surface of the examiner's hand has
been found to be the most sensitive, and by
moving the hand slowly up the child's body,
one can verify changes that one marks on the
skin and rechecks on repeat testing.
 Object discrimination can be determined in the
healthy school-aged child by the use of coin, or
small, familiar items such as paperclips or
rubber bands.
Neurologic examination of the
infant
A positive response to Babinski sign is seen
normally in the majority of 1-year-old children
and in many up to 2 1/2 years of age.
In the sequential examination of infants
conducted by Gingold and her group, the
plantar response becomes consistently flexor
between 4 and 6 months of age
Neurologic examination of the
infant
Several beats of ankle clonus can be
demonstrated in some healthy newborns and in
some tense older children.
A sustained ankle clonus is abnormal at any age
and suggests a lesion of the pyramidal tract.
Neurologic examination of the
infant
Children with developmental disabilities, such
as minimal brain dysfunction and attention-
deficit disorders, are often found to have soft
signs on neurologic examination
Neurologic examination of the
infant
These represent persistence of findings
considered normal at a younger age. Of the
various tests designed to elicit soft signs:
1. Tandem walking: is performed successfully
by 90% of 5-year-old children; 90% of 7-year-
old children also can hop in one place.
Neurologic examination of the
infant
1. Hopping on one foot.
2. Ability of the child to suppress overflow
movements when asked to repetitively touch
the index finger to the thumb.
Neurologic examination of the
infant
A positive response to Babinski sign is seen
normally in the majority of 1-year-old children
and in many up to 2 1/2 years of age .
In the sequential examination of infants
conducted by Gingold and her group, the
plantar response becomes consistently flexor
between 4 and 6 months of age
Neurologic examination of the
infant
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Neurological Examination of an infant

  • 2. Amr Hasan, MD,FEBN Associate Professor of Neurology - Cairo University
  • 3.
  • 4. •Neurological examination in pediatrics varies according to age e.g. : the approach to neonates will vary from that of children. •Observation is key to diagnosis since physical signs are usually less obvious than in adults. •Talk to the parents.
  • 5. •A child older than 3 to 5 years might provide information that not only is valuable, but also may be more reliable than that related by his or her parents. •Do not ask leading questions. •The physician also must be responsive to the youngster's mood and cease taking a history as soon as fatigue or restlessness becomes evident. •In a younger child or one with a limited attention span, the salient points of the history are best secured at the onset of the evaluation.
  • 6. •Allow older children play as you observe. •This may require that you have some toys. •Communicate with the children.
  • 7. •A review of the perinatal events is always in order. •Feeding history. •A history of abnormal sleeping habits. •Major childhood illnesses •Immunizations •Injuries •The family history
  • 8.
  • 9.
  • 10. •The toddler is more difficult to examine. The toddler is best approached by seating the child in the mother's or father's lap and talking to the child. •Because toddlers are fearful of strangers, the physician must first observe the youngster and defer touching him or her until some degree of rapport has been established.
  • 11. •Offering a small, interesting toy may bridge the gap. •Once frightened, most toddlers are difficult to reassure and are lost for the remainder of the examination.
  • 12. •The child's height, weight, blood pressure, and head circumference must always be measured and recorded. •The youngster should be undressed by the parents, with the physician absent. •The physician should note the general appearance of the child. • Note facial configuration,presence of any dysmorphic feature & Cutaneous lesions.
  • 13. •The condition of the teeth provides information about antenatal defects or kernicterus. •The location of the hair whorl and the appearance of the palmar creases should always be noted.
  • 14. •The quality of the scalp hair, eyebrows, and nails also should be taken into account. •It is important to inspect the midline of the neck, back, and pilonidal area for any defects, particularly for small dimples that might indicate the presence of a dermoid sinus tract.
  • 15. •Examination of chest, heart, and abdomen and palpation of the femoral pulses should always be part of the general physical examination. •Finally, the presence of an unusual body odor may offer a clue to a metabolic disorder.
  • 16. The neurologic examination of an infant younger than 1 year of age can be divided into three parts: 1. Evaluation of posture and tone 2. Evaluation of primitive reflexes 3. Age invariable tests.
  • 17. The neurologic examination of an infant younger than 1 year of age can be divided into three parts: 1. Evaluation of posture and tone 2. Evaluation of primitive reflexes 3. Age invariable tests.
  • 18. 1. Evaluation of posture and tone Evaluation of posture and muscle tone is a fundamental part of the neurologic examination of infants. It involves examination of: A. Resting Posture B. Passive Tone C. Active Tone
  • 19. 1.Evaluation of posture and tone: A. Resting Posture: Posture is appreciated by inspecting the undressed  During the first few months of life, normal hypertonia of the flexors of the elbows, hips, and knees occurs.  The hypertonia decreases markedly during the third month of life, first in the upper extremities and later in the lower extremities.
  • 20. 1.Evaluation of posture and tone: A. Resting Posture:  At the same time, tone in neck and trunk increases.  Between 8 and 12 months of age, a further decrease occurs in the flexor tone of the extremities together with increased extensor tone .
  • 21.
  • 22.
  • 23. 1. Evaluation of posture and tone B. Passive tone  Is accomplished by determining the resistance to passive movements of the various joints with the infant awake and not crying.  Because limb tone is influenced by tonic neck reflexes, it is important to keep the child's head straight during this part of the examination.
  • 24.
  • 25. 1. Evaluation of posture and tone B. Passive tone  Passive flapping of the hands and the feet provides a simple means of ascertaining muscle tone.  In the upper extremity, the scarf sign is a valuable maneuver.  In the lower extremity, the fall-away response serves a similar purpose.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33. 1. Evaluation of posture and tone: C. Active tone:  The traction response is an excellent means of ascertaining active tone  The examiner, who should be sitting down and facing the child, places his or her thumbs in the infant's palms and fingers around the wrists and gently pulls the infant from the supine position.
  • 34. 1. Evaluation of posture and tone: C. Active tone:  In the healthy infant younger than 3 months of age, the palmar grasp reflex becomes operative, the elbows tend to flex, and the flexor muscles of the neck are stimulated to raise the head so that even in the full-term neonate the extensor and flexor tone are balanced and the head is maintained briefly in the axis of the trunk.
  • 35.
  • 36.
  • 37.
  • 38. The neurologic examination of an infant younger than 1 year of age can be divided into three parts: 1. Evaluation of posture and tone 2. Evaluation of primitive reflexes 3. Age invariable tests.
  • 39. The neurologic examination of an infant younger than 1 year of age can be divided into three parts: 1. Evaluation of posture and tone 2. Evaluation of primitive reflexes 3. Age invariable tests.
  • 40. 2. Evaluation of primitive reflexes:  The evaluation of primitive reflexes is an integral part of the neurologic examination of the infant.  This disappearance should not be construed as meaning that they are actually lost, for a reflex once acquired in the course of development is retained permanently.
  • 41. 2. Evaluation of primitive reflexes:  Rather, these reflexes, which develop during intrauterine life, are gradually suppressed as the higher cortical centers become functional.
  • 42. 2. Evaluation of primitive reflexes: A. Segmental Medullary Reflexes: A number of segmental medullary reflexes become functional during the last trimester of gestation. They include (a) respiratory activity. (b) cardiovascular reflexes. (c) coughing reflex mediated by the vagus nerve. (d) sneezing reflex evoked by afferent fibers of the trigeminal nerve. (e)swallowing reflex mediated by the trigeminal and glossopharyngeal nerves. (f) sucking reflex.
  • 43. 2. Evaluation of primitive reflexes: B. Flexion Reflex:  This response is elicited by the unpleasant stimulation of the skin of the lower extremity, most consistently the dorsum of the foot, and consists of dorsiflexion of the great toe and flexion of the ankle, knee, and hip.
  • 44. 2. Evaluation of primitive reflexes: B. Flexion Reflex  This reflex has been elicited in immature fetuses and can persist as a fragment, the extensor plantar response, for the first 2 years of life. It is seen also in infants whose higher cortical centers have been profoundly damaged.
  • 45. 2. Evaluation of primitive reflexes: C. Moro Reflex The Moro reflex is best elicited by a sudden dropping of the baby's head in relation to its trunk. Moro, however, elicited this reflex by hitting the infant's pillow with both hands.
  • 46. 2. Evaluation of primitive reflexes: C. Moro Reflex  The infant opens the hands, extends and abducts the upper extremities, and then draws them together. The reflex first appears between 28 and 32 weeks' gestation and is present in all newborns.  It fades out between 3 to 5 months of age. 
  • 47. 2. Evaluation of primitive reflexes: C. Moro Reflex Its persistence beyond 6 months of age or its absence or diminution during the first few weeks of life indicates neurologic dysfunction.
  • 48.
  • 49.
  • 50. 2. Evaluation of primitive reflexes: D. Tonic Neck Response The tonic neck response is obtained by rotating the infant's head to the side while maintaining the chest in a flat position. A positive response is extension of the arm and leg on the side toward which the face is rotated and flexion of the limbs on the opposite side .
  • 51. 2. Evaluation of primitive reflexes: D. Tonic Neck Response Inconstant tonic neck responses can be elicited for as long as 6 to 7 months of age and can even be momentarily present during sleep in the healthy 2- to 3-year-old child .
  • 52.
  • 53.
  • 54.
  • 55. 2. Evaluation of primitive reflexes: E.Righting Reflex  With the infant in the supine position, the examiner turns the head to one side. The healthy infant rotates the shoulder in the same direction, followed by the trunk, and finally the pelvis.  An obligate neck-righting reflex in which the shoulders, trunk, and pelvis rotate simultaneously and in which the infant can be rolled over and over like a log is always abnormal.
  • 56.
  • 57. 2. Evaluation of primitive reflexes: F. Palmar and Plantar Grasp Reflexes  The palmar and plantar grasp reflexes are elicited by pressure on the palm or sole.  Generally, the plantar grasp reflex is weaker than the palmar reflex.
  • 58. 2. Evaluation of primitive reflexes: F. Palmar and Plantar Grasp Reflexes:  The palmar grasp reflex appears at 28 weeks' gestation, is well established by 32 weeks, and becomes weak and inconsistent between 2 and 3 months of age, when it is covered up by voluntary activity.
  • 59. 2. Evaluation of primitive reflexes: F. Palmar and Plantar Grasp Reflexes:  Absence of the reflex before 2 or 3 months of age, persistence beyond that age, or a consistent asymmetry is abnormal.  The reappearance of the grasp reflex in frontal lobe lesions reflects the unopposed parietal lobe activity.
  • 60.
  • 61. 2. Evaluation of primitive reflexes: G.Vertical Suspension  The examiner suspends the child with his or her hand under its axillae and notes the position of the lower extremities.  Marked extension or scissoring is an indication of spasticity.
  • 62.
  • 63. 2. Evaluation of primitive reflexes: H.Landau Reflex  To elicit the Landau response, the examiner lifts the infant with one hand under the trunk, face downward.  Normally, a reflex extension of the vertebral column occurs, causing the newborn infant to lift the head to slightly below the horizontal, which results in a slightly convex upward curvature of the spine. With hypotonia, the infant's body tends to collapse into an inverted U shape.
  • 64.
  • 65. 2. Evaluation of primitive reflexes: H.Landau Reflex  With hypotonia, the infant's body tends to collapse into an inverted U shape.
  • 66.
  • 67. 2. Evaluation of primitive reflexes: I.Buttress Response  To elicit the buttress response, the examiner places the infant in the sitting position and displaces the center of gravity with a gentle push on one shoulder.
  • 68. 2. Evaluation of primitive reflexes: I.Buttress Response  The infant extends the contralateral arm and spreads the fingers.  The reflex normally appears at approximately 5 months of age. Delay in its appearance and asymmetries are significant.
  • 69. 2. Evaluation of primitive reflexes: J.Parachute Response  The parachute reflex is tested with the child suspended horizontally about the waist, face down.  The infant is then suddenly projected toward the floor, with a consequent extension of the arms and spreading of the fingers.
  • 70. 2. Evaluation of primitive reflexes: J.Parachute Response:  Between 4 and 9 months of age, this reflex depends on visual and vestibular sensory input and is proportional to the size of the optic stimulus pattern on the floor.
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  • 72. 2. Evaluation of primitive reflexes: K.Reflex Placing and Stepping Responses  Reflex placing is elicited by stimulating the dorsum of the foot against the edge of the examining table.  Reflex stepping, which is at least partly a function of the flexion response, is present in the healthy newborn when the infant is supported in the standing position; it disappears in the fourth or fifth month of life.
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  • 74.
  • 75. 2. Evaluation of primitive reflexes: L.Reflex Suck, Root
  • 76.  exam video06 Func_int-DevRfx.mpg
  • 77. The neurologic examination of an infant younger than 1 year of age can be divided into three parts: 1. Evaluation of posture and tone 2. Evaluation of primitive reflexes 3. Age invariable tests.
  • 78. The neurologic examination of an infant younger than 1 year of age can be divided into three parts: 1. Evaluation of posture and tone 2. Evaluation of primitive reflexes 3. Age invariable tests.
  • 79. 3.Age-Invariable Tests The last part of the neurologic examination involves tests similar to those performed in older children or adults, such as the funduscopic examination and the deep tendon reflexes.
  • 80. •In addition to the standard instruments used in neurologic examination, the following have been found useful: •a tennis ball •few small toys •a bell •some object that attracts the child's attention (e.g., a pinwheel).
  • 81. •In most intellectually healthy school-aged children, the general physical and neurologic examinations can be performed in the same manner as for adults •Except that fundus examination, corneal and gag reflexes and sensory testing, should be postponed until the end.
  • 82. Olfactory Nerve Olfactory sensation as transmitted by the olfactory nerve is not functional in the newborn, but is present by 5 to 7 months of age.
  • 84. Optic Nerve •In infants, the optic disc is normally pale and gray, an appearance similar to optic atrophy in later life. •Premature and newborn infants have incompletely developed uveal pigment, resulting in a pale appearance of the fundus and a clear view of the choroidal blood vessels.
  • 85. Optic Nerve •Retinal hemorrhages are seen in one-third of vaginally delivered newborns. •They are usually small and multiple, and their presence does not necessarily indicate intracranial bleeding.
  • 86. Optic Nerve Visual acuity can be tested in the older child by standard means. In the toddler, an approximation can be obtained by observing him or her at play or by offering objects of varying sizes.
  • 87. Optic Nerve Optokinetic nystagmus can be elicited by rotating a striped drum or by drawing a strip of cloth with black and white squares in front of the child's eyes. The presence of optokinetic nystagmus confirms cortical vision; its absence, however, is inconclusive.
  • 88. Optic Nerve The blink reflex, closure of the eyelids when an object is suddenly moved toward the eyes, is often used to determine the presence of functional vision in small infants.
  • 89. Optic Nerve The macular light reflex is absent until approximately 4 months of age. It is present in approximately one-half of healthy 5-month-old infants and should be present in all infants by 1 year of age
  • 90. Optic Nerve The visual fields can be assessed in toddlers and in infants younger than 12 months of age. The baby is placed in the mother's lap and the physician is seated in front of them, using a small toy to attract the baby's attention. Neurologic examination of the infant
  • 91. Optic Nerve An assistant standing in back of the infant brings another object into the field of vision, and the point at which the infant's eyes or head turns toward the object is noted. Neurologic examination of the infant
  • 92. Oculomotor, Trochlear, and Abducens Nerves: Extraocular Movements The physician notes the position of the eyes at rest. Noting the points of reflection of a flashlight assists in detecting a nonparallel alignment of the eyes. The size of the pupils, their reactivity to light, and accommodation and convergence are noted.
  • 93. Neurologic examination of the infant Oculomotor, Trochlear, and Abducens Nerves: Extraocular Movements A slight degree of anisocoria is not unusual, particularly in infants and small children. Fatigue-induced anisocoria also has been noted to be transmitted as an autosomal dominant trait
  • 94. Neurologic examination of the infant Oculomotor, Trochlear, and Abducens Nerves: Extraocular Movements Following movements are complete in all directions by approximately 4 months of age, and acoustically elicited eye movements appear at 5 months of age . Depth perception using solely binocular cues appears by 24 months of age along with stable binocular alignment and optokinetic nystagmus.
  • 95. Neurologic examination of the infant Trigeminal Nerve The corneal reflex tests the intactness of the ophthalmic branch of the trigeminal nerve. A defect should be suspected when spontaneous blinking on one side is slower and less complete. The frequency of blinking increases with maturation and decreases in toxic illnesses.
  • 96. Facial Nerve •Impaired motor function is indicated by facial asymmetry. •The McCarthy reflex, ipsilateral blinking produced by tapping the supraorbital region, is diminished or absent in lower motor neuron facial weakness. • Neurologic examination of the infant
  • 97. Facial Nerve •Palpebral reflex, bilateral blinking induced by tapping the root of the nose, it can be exaggerated by upper motor neuron lesions. •In hemiparesis or peripheral facial nerve weakness, the contraction of the platysma muscle is less vigorous on the affected side, This sign also carries Babinski's name. Neurologic examination of the infant
  • 98. Facial Nerve An isolated weakness of the depressor of the corner of the mouth (depressor anguli oris) is relatively common in children. It results in a failure to pull the affected side of the mouth backward and downward when crying. Neurologic examination of the infant
  • 101. Cochlear Nerve •Hearing can be tested in the younger child by observing the child's response to a bell. •Small infants become alert to sound; the ability to turn the eyes to the direction of the sound becomes evident by 7 to 8 weeks of age, and turning with eyes and head appears by approximately 3 to 4 months of age. Neurologic examination of the infant
  • 102. Cochlear Nerve •Hearing is tested in older children by asking them to repeat a whispered word or number. •For more accurate evaluation of hearing, audiometry or brainstem auditory-evoked potentials are necessary. Neurologic examination of the infant
  • 103. Vestibular Nerve •Vestibular function can be assessed easily in infants or small children by holding the youngster vertically so he or she is facing the examiner, then turning the child several times in a full circle. •Clockwise and counterclockwise rotations are performed. The direction and amplitude of the quick and slow movements of the eye are noted. Neurologic examination of the infant
  • 104. Vestibular Nerve •The healthy infant demonstrates full deviation of the eyes in the direction that he or she is being rotated with the quick phase of the nystagmus backward. When rotation ceases, these directions are reversed. Neurologic examination of the infant
  • 105. Glossopharyngeal and Vagus Nerves •The gag reflex tests the afferent and efferent portions of the vagus. •This reflex is absent in approximately one-third of healthy individuals. •Testing taste over the posterior part of the tongue is extremely difficult and, according to some opinions, generally not worth the effort. Neurologic examination of the infant
  • 106. Spinal Accessory Nerve Testing the sternocleidomastoid muscle can be done readily by having the child rotate his or her head against resistance. Neurologic examination of the infant
  • 107. Hypoglossal Nerve •The position of the tongue at rest should be noted with the mouth open. •The tongue deviates toward the paretic side. •Fasciculations are seen as small depressions that appear and disappear quickly at irregular intervals. Neurologic examination of the infant
  • 108. Hypoglossal Nerve •They are most readily distinguished on the underside of the tongue. •Their presence cannot be determined with any reliability if the youngster is crying. Neurologic examination of the infant
  • 109. Motor system examination: •Similarly, the walking and running gaits can be seen by playing with the youngster and asking him or her to retrieve a ball and run outside of the examining room. •In the course of such an informal examination, sufficient information can be obtained so that the formal testing of muscle strength is only confirmatory. Neurologic examination of the infant
  • 110. In toddlers or infants, inequalities of tone have been found to provide more information than assessment of muscle strength or reflexes. A sensitive test for weakness of the upper extremities is the pronator sign, in which the hand on the hypotonic side hyperpronates to palm outward as the arms are raised over the head. Additionally, the elbow may flex . Neurologic examination of the infant
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  • 112. In the lower extremities, weakness of the flexors of the knee can readily be demonstrated by having the child lie prone and asking the child to maintain his or her legs in flexion at right angles at the knee. An unsustained ankle clonus is common in the healthy neonate. Neurologic examination of the infant
  • 113. Coordination Coordination can be tested by applying specific tests for cerebellar function, such as having the youngster reach for and manipulate toys. The ability to perform rapidly alternating movements can be assessed by having the child repeatedly pat the examiner's hand, or by having the child perform rapid pronation and supination of the hands. Neurologic examination of the infant
  • 114. Coordination The heel-to-shin test is not an easy task for many youngsters to comprehend, and performance must be interpreted with regard to the child's age and level of intelligence. Neurologic examination of the infant
  • 115.  A proper sensory examination is difficult at any age, and almost impossible in an infant or toddler.  In infants or toddlers, abnormalities in skin temperature or in the amount of perspiration indicate the level of sensory deficit. Neurologic examination of the infant
  • 116.  The ulnar surface of the examiner's hand has been found to be the most sensitive, and by moving the hand slowly up the child's body, one can verify changes that one marks on the skin and rechecks on repeat testing.  Object discrimination can be determined in the healthy school-aged child by the use of coin, or small, familiar items such as paperclips or rubber bands. Neurologic examination of the infant
  • 117. A positive response to Babinski sign is seen normally in the majority of 1-year-old children and in many up to 2 1/2 years of age. In the sequential examination of infants conducted by Gingold and her group, the plantar response becomes consistently flexor between 4 and 6 months of age Neurologic examination of the infant
  • 118. Several beats of ankle clonus can be demonstrated in some healthy newborns and in some tense older children. A sustained ankle clonus is abnormal at any age and suggests a lesion of the pyramidal tract. Neurologic examination of the infant
  • 119. Children with developmental disabilities, such as minimal brain dysfunction and attention- deficit disorders, are often found to have soft signs on neurologic examination Neurologic examination of the infant
  • 120. These represent persistence of findings considered normal at a younger age. Of the various tests designed to elicit soft signs: 1. Tandem walking: is performed successfully by 90% of 5-year-old children; 90% of 7-year- old children also can hop in one place. Neurologic examination of the infant
  • 121. 1. Hopping on one foot. 2. Ability of the child to suppress overflow movements when asked to repetitively touch the index finger to the thumb. Neurologic examination of the infant
  • 122. A positive response to Babinski sign is seen normally in the majority of 1-year-old children and in many up to 2 1/2 years of age . In the sequential examination of infants conducted by Gingold and her group, the plantar response becomes consistently flexor between 4 and 6 months of age Neurologic examination of the infant