This is a slide to explain target prioritization.

1. Candidate gene prioritization
>NSA2_HUMAN Ribosome biogenesis
>APOB_HUMAN Apolipoprotein B-100
>CD99_HUMAN CD99 antigen
>MAVS_HUMAN Mitochondrial antiviral
>CA031_HUMAN Uncharacterized protein
>CA043_HUMAN Uncharacterized protein
>CA049_HUMAN Uncharacterized protein
…
Large-scale
experiments
A number of target
candidates
Stop development
1. Lack of annotations for individual genes
2. Difficulties in combining available
information from different data sources
This work by Kenji Mizuguchi is licensed under a Creative Commons Attribution 4.0 International License.

2. Gene 1
Gene 2
Gene 3
Gene 4
Gene 5
….
….
….
Gene 200
Gene 4
Gene 17
Gene 45
Gene 87
Integrated knowledge
discovery
INPUT OUTPUT
Many
candidates
Selected
targets
This work by Kenji Mizuguchi is licensed under a Creative Commons Attribution 4.0 International License.