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Jagdish Dukre
Biometry is the process of measuring the 
power of the cornea (keratometry) and the 
Axial length of the eye, and using this data to 
determine the ideal intraocular lens power.
Measuring the axial length of the eye 
Axial length of the eye is measured with A scan 
ultrasonography. 
An 1-mm error in measurement of axial length produces 
an error of 3 D in IOL calculation.
For accurate measurement of axial length (using 
applanation): 
 ensure the machine is calibrated and set for the correct 
velocity setting (e.g. cataract, aphakia, pseudophakia) 
 take care with axial alignment, especially with a hand-held 
probe and a moving patient.
 the gain should be set at the lowest level at which a good reading 
is obtained. 
 don’t push too hard – corneal compression commonly causes 
errors. 
 the echoes from cornea, anterior lens, posterior lens, and retina 
should be present and of good amplitude misalignment along the 
optic nerve is recognised by an absent scleral spike. 
 average the 5-10 most consistent results giving the lowest 
standard deviation (ideally < 0.06 mm) 
 errors may arise from an insufficient or greasy corneal meniscus 
due to ointment or methylcellulose used previously.
Measuring the power of the cornea 
 Keratometry may be carried out manually or using an 
automated or hand-held device. 
 Accuracy is essential, as an error of 0.75 D in the 
keratometry will result in a similar post-operative error.
For accurate manual keratometry : 
 ensure a good tear film 
 adjust the eyepiece to bring the central cross-hairs into 
focus. 
 make sure that the patient’s other eye is occluded and 
that the cornea is centred 
 take an average of three readings. 
 if high or low results are encountered (< 40.00 D or > 
48.00 D), it is advisable to have a second check. 
 repeat if the difference in total keratometric power 
between the eyes exceeds 1.50 D 
 in a scarred cornea, use the fellow eye or average the 
results.
IOL Formulae 
 First generation 
 Second generation 
 Third generation 
 Fourth generation
First generation 
Theoretical 
1. Binkhorst 
2. Colenbrander-Hoffer 
3. Gilll’s 
4. Clayman 
5. Fyodorov 
Regression 
SRK - I
Second 
generation 
Theoretical 
Modified Binkhorst 
Regression 
SRK - II
Third generation 
 Holladay I 
 SRK/T 
 Hoffer Q
Fourth generation 
 Holladay - II
Biometry after keratorefractive surgery 
 Anterior surface is flattened with no change in the 
posterior radius. 
 This causes error in keratometry leading to hyperopic 
IOL estimation.
The methods to calculate K values in a Post LASIK eye: 
 Clinical history 
 Contact lens correction 
 Topography
Clinical history 
 It is considered the gold standard. 
 For this method, keratometric values and the 
manifest refraction (MR) from before the 
refractive surgery as well as MR at appropriate 
intervals after the refractive procedure are 
needed. 
 The data is used to calculate the change in MR 
from pre to post refractive surgery
 That value is subtracted from the original 
keratometric value to obtain the “effective 
Keratometric Value” for use in IOL power 
calculation. 
 In this method the post-op MR value that 
should be used is the most recent one 
obtained before Cataract development as 
refraction is effected by the lens change.
Contact lens correction 
 It is based on the principle that if a contact 
lens of base curve(B) is equal effective power 
of the cornea then there would be no change 
in the refractive error with/without the 
contact lens.
Topography 
 This is not very accurate. 
 This is used when Preop ‘K’ is not known in a 
dense cataract patient. 
 A CVK derived mean anterior corneal curvature 
value calculated for a specific 3 mm central 
region of cornea, modified based on the amount 
of surgicallyinduced refraction change, is used. 
 But this is not as accurate as other techniques; 
because ablative procedure changes 
standardised index of Refraction (SIR). 
 There is 1D overestimation for change of 7D 
during the refractive surgery.
Pediatric biometry 
 Pediatric eye is not a miniaturized adult eye. 
 It has shorter axial length, steeper cornea with 
higher keratometry value and smaller anterior 
chamber depth. 
 Errors in axial length measurement affect IOL 
power calculation the most, it increases to 3.75 D 
per mm in children. 
 In small eyes with congenital cataract the lens is a 
greater proportion of the total axial length and 
therefore the average velocity would be faster.
 no formula has been proven to have an advantage 
over others. 
 newer theoretic formulas such as Holladay II that 
take anterior segment measurements into account, 
may be recommended for pediatric IOL power 
calculation. 
 20% undercorrection if the child is less than age 2 
years 10% undercorrection for age 2–8 years .
Biometry in aphakia 
 Two lens spikes are absent 
 Velocity is decreased
Biometry in pseudophakia 
 High spike at the lens 
 Holladay formula 
 TAL = 0.988(AAL) + T[1-(1532/V)]
Secondary piggyback IOL 
 Only refractive error is required. 
 Holladay Refractive formula 
 Hyperopic error : piggyback IOL = 1.5 x R 
 Myopic error : piggyback IOL = 1 x R 
 Where R = postoperative spherical 
equivalent refractive error.
THANK 
YOU

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Biometry

  • 2. Biometry is the process of measuring the power of the cornea (keratometry) and the Axial length of the eye, and using this data to determine the ideal intraocular lens power.
  • 3. Measuring the axial length of the eye Axial length of the eye is measured with A scan ultrasonography. An 1-mm error in measurement of axial length produces an error of 3 D in IOL calculation.
  • 4. For accurate measurement of axial length (using applanation):  ensure the machine is calibrated and set for the correct velocity setting (e.g. cataract, aphakia, pseudophakia)  take care with axial alignment, especially with a hand-held probe and a moving patient.
  • 5.  the gain should be set at the lowest level at which a good reading is obtained.  don’t push too hard – corneal compression commonly causes errors.  the echoes from cornea, anterior lens, posterior lens, and retina should be present and of good amplitude misalignment along the optic nerve is recognised by an absent scleral spike.  average the 5-10 most consistent results giving the lowest standard deviation (ideally < 0.06 mm)  errors may arise from an insufficient or greasy corneal meniscus due to ointment or methylcellulose used previously.
  • 6. Measuring the power of the cornea  Keratometry may be carried out manually or using an automated or hand-held device.  Accuracy is essential, as an error of 0.75 D in the keratometry will result in a similar post-operative error.
  • 7. For accurate manual keratometry :  ensure a good tear film  adjust the eyepiece to bring the central cross-hairs into focus.  make sure that the patient’s other eye is occluded and that the cornea is centred  take an average of three readings.  if high or low results are encountered (< 40.00 D or > 48.00 D), it is advisable to have a second check.  repeat if the difference in total keratometric power between the eyes exceeds 1.50 D  in a scarred cornea, use the fellow eye or average the results.
  • 8. IOL Formulae  First generation  Second generation  Third generation  Fourth generation
  • 9. First generation Theoretical 1. Binkhorst 2. Colenbrander-Hoffer 3. Gilll’s 4. Clayman 5. Fyodorov Regression SRK - I
  • 10. Second generation Theoretical Modified Binkhorst Regression SRK - II
  • 11. Third generation  Holladay I  SRK/T  Hoffer Q
  • 12. Fourth generation  Holladay - II
  • 13. Biometry after keratorefractive surgery  Anterior surface is flattened with no change in the posterior radius.  This causes error in keratometry leading to hyperopic IOL estimation.
  • 14. The methods to calculate K values in a Post LASIK eye:  Clinical history  Contact lens correction  Topography
  • 15. Clinical history  It is considered the gold standard.  For this method, keratometric values and the manifest refraction (MR) from before the refractive surgery as well as MR at appropriate intervals after the refractive procedure are needed.  The data is used to calculate the change in MR from pre to post refractive surgery
  • 16.  That value is subtracted from the original keratometric value to obtain the “effective Keratometric Value” for use in IOL power calculation.  In this method the post-op MR value that should be used is the most recent one obtained before Cataract development as refraction is effected by the lens change.
  • 17. Contact lens correction  It is based on the principle that if a contact lens of base curve(B) is equal effective power of the cornea then there would be no change in the refractive error with/without the contact lens.
  • 18. Topography  This is not very accurate.  This is used when Preop ‘K’ is not known in a dense cataract patient.  A CVK derived mean anterior corneal curvature value calculated for a specific 3 mm central region of cornea, modified based on the amount of surgicallyinduced refraction change, is used.  But this is not as accurate as other techniques; because ablative procedure changes standardised index of Refraction (SIR).  There is 1D overestimation for change of 7D during the refractive surgery.
  • 19. Pediatric biometry  Pediatric eye is not a miniaturized adult eye.  It has shorter axial length, steeper cornea with higher keratometry value and smaller anterior chamber depth.  Errors in axial length measurement affect IOL power calculation the most, it increases to 3.75 D per mm in children.  In small eyes with congenital cataract the lens is a greater proportion of the total axial length and therefore the average velocity would be faster.
  • 20.  no formula has been proven to have an advantage over others.  newer theoretic formulas such as Holladay II that take anterior segment measurements into account, may be recommended for pediatric IOL power calculation.  20% undercorrection if the child is less than age 2 years 10% undercorrection for age 2–8 years .
  • 21.
  • 22. Biometry in aphakia  Two lens spikes are absent  Velocity is decreased
  • 23. Biometry in pseudophakia  High spike at the lens  Holladay formula  TAL = 0.988(AAL) + T[1-(1532/V)]
  • 24. Secondary piggyback IOL  Only refractive error is required.  Holladay Refractive formula  Hyperopic error : piggyback IOL = 1.5 x R  Myopic error : piggyback IOL = 1 x R  Where R = postoperative spherical equivalent refractive error.

Notes de l'éditeur

  1. with an average error of 2.5 D per millimeter of axial length in adults;