8. Both concepts are based on
INFORMATION
A meaningful set of data or patterns which influence the formation or
transformation of other data or patterns, in order to reduce uncertainty
and help achieve a goal
10. How to increase information
content
1. Enriched environment, hormetic challenges
2. Social hyper-connectivity (real and virtual/online)
3. Behavioural models: goal-seeking behavior, search for excellence, a bias for action
4. The pursuit of innovation, diversification, creativity, novelty, and the avoidance of routine.
11. Hormesis
An adaptive response of cells and
organisms to a moderate,
intermittent, challenge.
Hormesis describes phenomena
where there is low dose
stimulation, high dose inhibition.
Nutritional, physical, mental and
chemical challenges may result in
mild damage which upregulates
repair mechanisms. In an attempt
to repair this damage, age-related
damage is also repaired.
13. Environmental Enrichment
Experimental animals are
exposed to an enriched
environment- a habitat
augmentation. This has
several positive effects on
health, specifically on
brain and immune
function.
14. Challenge
Here, a challenge is defined as a situation that potentially carries
biological value for an organism, so that the organism is inclined to act.
A challenge provokes action because it represents a situation in which
not acting will lead to an overall lower fitness than acting.
15. The balance between age-related degeneration and health depends on:
A. How well our repair processes are maintained through artificial (item-based)
pharmacological, genetic, cellular, biotechnological and other physical interventions.
B. Through utilising challenging exposure to information with consequent
improvement of function.
19. An Irregular, Useful
Guest
Second, usefulness
• Humanity is not going to improve if its members
don't make an effort to achieve something higher.
Third, quest
• Always seek novelty, never be satisfied, never sit
quiet and 'relax' for long periods. Be inquisitive,
always ask 'why' and don't take anything at face
value.
• Try to get to the top but don't stop there. There is
always something higher.
• Come up with new ideas, and then try to achieve
them.
First, irregularity
We thrive on change, challenges
and unexpected events.
A ‘power-law’ lifestyle: frequent
low level activities, some medium
level ones, and rare intense
activities.
Ever-changing, imaginative and
unpredictable activities improve
immunity, reduce inflammation,
improve nerve-growth factors, and
many others.
20. The end?
ELPIs Foundation for Indefinite
Lifespans
www.elpisfil.org
drmarios@live.it
Meeting to discuss these concepts: 3rd
Symposium ‘Pathways to Indefinite
Lifespans’
0n Saturday 23 May 2015, In Larnaca,
Cyprus