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COMPARATIVE ANALYSIS OF LEAD FREE PIEZOELECTRIC MATERIAL FOR
ULTRSONIC GLUCOSE SENSING APPLICATIONS
1
Abstract
This Paper describes the design of an ultrasonic transducer using different lead free piezo-
electric materials and evaluates their performance in the human blood medium. COMSOL
Multiphysics 5.1 is used for the simulation study where a 2D axis- symmetric model geometry of
piezoelectric transducer was designed with lead free piezoelectric materials such as Barium
Sodium Niobate (Ba2NaNb5O15)(BNN), Barium Titanate (BaTiO3), Lithium Niobate (LiNbO3)
(LN) and zinc oxide. These piezoelectric materials are capable of being used as thin films. The
potential of 1.6 Volt with 350MHz frequency was applied to the device. The geometry of the
sample container for blood is a sector with 90 degrees and radius of 3 micrometers. The surface and
radial displacement of the transducer structure of the materials with pressure and stress are studied
in liquid blood medium. The ultrasonic transducer with these piezo materials was observed
showing different transducer response in the blood medium and therefore, it can be used to measure
the glucose levels in the human blood. However, the Zno has shown better performance compared
to others. The glucose level of blood samples were also compared with a commercial glucometer.
December 22, 2023 2
ICACT19-EC-70
Introduction
• To prevent complications in diabetes, accurate monitoring of blood glucose
levels is important.
• Regular monitoring of sugar level in patient can alarm many unwanted rise
in the level and necessary precautions can be taken at the right time .
• Glucose meters are supposed to be a solution for continuous monitoring of
sugar level.
December 22, 2023 3
ICACT19-EC-70
Different techniques for glucose monitoring:
Invasive Minimally invasive
December 22, 2023 4
ICACT19-EC-70
Present techniques (Non-Invasive methods):
• Infrared and Near-infrared absorption spectroscopy
• Near-infrared scattering technique
December 22, 2023 5
ICACT19-EC-70
December 22, 2023 ICACT19-EC-70 6
 Photo acoustic spectroscopy
Bio impedance spectroscopy
Cont…
Biosensor
• A sensor that integrates a biological element with physiochemical
transducer to produce an electronic signal proportional to signal analyte
which is then conveyed to detector
December 22, 2023 7
ICACT19-EC-70
Ultrasonic transducer method can be used to determine the
glucose levels of human blood by studying the variation of
amplitude with density of blood sample with glucose and it can
be calibrated and compared to determine the sugar level.
Ultrasonic Transducer Model for Biosensor
December 22, 2023 8
ICACT19-EC-70
Ultrasonic:
It is a phenomenon that has the frequency above the hearing capability of
human ear.
• Ultrasonic transducer
It is a device that converts energy into ultrasonic waveform and vice versa
December 22, 2023 9
ICACT19-EC-70
Piezoelectric materials:-
• Offer a high pressure per density ratio for the actuator,
• High stability in hostile environment
• Chemically they are very stable.
For making ultrasonic transducers and piezoelectric actuators, it is
desirable to have
• High electromechanical coupling coefficients
• Relatively large dielectric constant
• Large piezoelectric coefficient.
December 22, 2023 10
ICACT19-EC-70
Lead free Piezo Materials
 Lead Zirconate Titanate (PZT) has been recognized as an environmentally
non-friendly material which contains more than 60% lead by weight .
 Unfortunately, among the existing lead-free ferroelectric crystals, some
have weak piezoelectricity and some are very expensive to fabricate.
 Different lead free piezoelectric materials like
◦ Barium Sodium Niobate (Ba2NaNb5O15)(BNN),
◦ Barium Titanate (BaTiO3)(BT)
◦ Lithium Niobate (LiNbO3) (LN)
December 22, 2023 11
ICACT19-EC-70
 Conventional ultrasonic transducer systems became very bulky and power
hungry.
 Hence we switched over to Micro-electro mechanical system (MEMS)
 MEMS based acoustic bio-sensing transducer is based on the piezoelectric
technology which exploits the nature and properties of the propagating
ultrasonic wave in blood medium of various densities
MEMS
December 22, 2023 12
ICACT19-EC-70
Model geometry and boundary conditions of
ultrasonic transducer
Fig 1: 2D axis symmetry
model
Fig 2:Pressure acoustics
December 22, 2023 13
ICACT19-EC-70
Piezoelectric film under stress
December 22, 2023 14
ICACT19-EC-70
15
Acoustic pressure waveforms
Fig 3: Pressure acoustic wave form Fig 4: sound acoustic waveform
December 22, 2023 ICACT19-EC-70
Acoustic pressure wave form (BNN)
Fig 5: Pressure acoustic wave form of BNN Fig 6: sound acoustic waveform of BNN
December 22, 2023 16
ICACT19-EC-70
Acoustic pressure wave form (BT)
Fig 7: Pressure acoustic wave form of BT Fig 8: sound acoustic waveform of BT
December 22, 2023 17
ICACT19-EC-70
Acoustic pressure wave form (LN)
Fig 9: Pressure acoustic wave form of LN Fig 10: sound acoustic waveform of LN
December 22, 2023 18
ICACT19-EC-70
Acoustic pressure wave form (Zn)
Fig 11: Pressure acoustic wave form of ZN Fig 12: sound acoustic waveform of ZN
December 22, 2023 19
ICACT19-EC-70
Far field polar graphs for BNN
Fig 13: Far field pressure polar graph BNN Fig 14: Far field sound polar graph BNN
December 22, 2023 20
ICACT19-EC-70
Far field polar graphs BT
Fig15: Far field pressure polar graph BT Fig 16:Far field sound polar graph BT
December 22, 2023 21
ICACT19-EC-70
Far field polar graphs(LN)
Fig17: Far field pressure polar graph LN Fig 18:Far field sound polar graph LN
December 22, 2023 22
ICACT19-EC-70
Far field polar graphs(ZN)
Fig 19:Far field pressure polar graph ZN Fig 20:Far field sound polar graph ZN
December 22, 2023 23
ICACT19-EC-70
Comparison between lead and lead-free materials
0
1
2
3
4
0 2 4 6
Zno
Pzt
blood sample Zno Pzt
1
3.47 3.35
2
0.8675 0.795
3
0.3855 0.2575
4
0.2168 0.1568
5
0.138 0.075
December 22, 2023 24
ICACT19-EC-70
Blood
Sample
Pressure
generated by
LIN
Pressure
generated by
BNN
Pressure
generated by
BT
Pressure
generated by
Zno
1 -255.2156377 -1564.508718 -3765.337914 -349.1934105
2 -255.2495062 -1564.715697 -3765.832407 -361.2346103
3 -255.4140098 -1565.721021 -3768.234204 -368.2795124
4 -255.590608 -1566.800254 -3770.812553 -373.2788144
5 -255.8663893 -1568.485608 -3774.838906 -377.2024183
Comparison between lead-free materials
1
2
3
4
5
Lin
BNN
BT
Zno
December 22, 2023 25
ICACT19-EC-70
Conclusion
• From the property of different lead free piezoelectric materials with
different glucose concentrations of blood sample medium displacement and
pressure are simulated using software COMSOL Multiphysics 5.1.
• It was found that Zno has shown better performance compare to others.
December 22, 2023 26
ICACT19-EC-70
References
 Pra dhan S K., Kamilla S K, Das, D P (2012), “Studies of Lead Free Piezo-Electric Materials Based Ultrasonic MEMS
Model for Bio Sensor”, In Proceeding of COMSOL Conference,ISBN: 978-0-9839688-2-5.
• Eun-Joo Park, Jacob Werner, Joshua Beebe, Samantha Chan, Nadine Barrie Smith, “Noninvasive Ultrasonic Glucose Sensing
with Large Pigs (~200 Pounds) Using a Lightweight Cymbal Transducer Array and Biosensors” Journal of Diabetes Science
and Technology, 3(3), pp-517-523, (2009).
• D.W.Greve, I.J. Oppenheim, “Coupling of MEMS Ultrasonic Transducer”, Proceedings of IEEE, Sensors, (2), pp 814 – 819,
(2003).
• K.Miranji, Dr R sandanalakshmi., “A Technology Overview and Future Scope of Bio-Mems in Tropical Disease Detection:
Review”
• Tao Li, Yanhong Chen, and Jan Ma,” Development of a Miniaturized Piezoelectric Ultrasonic Transducer” IEEE Transactions
on Ultrasonic's, Ferroelectrics, and Frequency Control, 56 (3), 649-659, (2009).
December 22, 2023 27
ICACT19-EC-70
December 22, 2023 ICACT19-EC-70 28
Thank You…..

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COMPARATIVE ANALYSIS OF LEAD FREE PIEZOELECTRIC MATERIAL FOR ULTRSONIC GLUCOSE SENSING APPLICATIONS

  • 1. COMPARATIVE ANALYSIS OF LEAD FREE PIEZOELECTRIC MATERIAL FOR ULTRSONIC GLUCOSE SENSING APPLICATIONS 1
  • 2. Abstract This Paper describes the design of an ultrasonic transducer using different lead free piezo- electric materials and evaluates their performance in the human blood medium. COMSOL Multiphysics 5.1 is used for the simulation study where a 2D axis- symmetric model geometry of piezoelectric transducer was designed with lead free piezoelectric materials such as Barium Sodium Niobate (Ba2NaNb5O15)(BNN), Barium Titanate (BaTiO3), Lithium Niobate (LiNbO3) (LN) and zinc oxide. These piezoelectric materials are capable of being used as thin films. The potential of 1.6 Volt with 350MHz frequency was applied to the device. The geometry of the sample container for blood is a sector with 90 degrees and radius of 3 micrometers. The surface and radial displacement of the transducer structure of the materials with pressure and stress are studied in liquid blood medium. The ultrasonic transducer with these piezo materials was observed showing different transducer response in the blood medium and therefore, it can be used to measure the glucose levels in the human blood. However, the Zno has shown better performance compared to others. The glucose level of blood samples were also compared with a commercial glucometer. December 22, 2023 2 ICACT19-EC-70
  • 3. Introduction • To prevent complications in diabetes, accurate monitoring of blood glucose levels is important. • Regular monitoring of sugar level in patient can alarm many unwanted rise in the level and necessary precautions can be taken at the right time . • Glucose meters are supposed to be a solution for continuous monitoring of sugar level. December 22, 2023 3 ICACT19-EC-70
  • 4. Different techniques for glucose monitoring: Invasive Minimally invasive December 22, 2023 4 ICACT19-EC-70
  • 5. Present techniques (Non-Invasive methods): • Infrared and Near-infrared absorption spectroscopy • Near-infrared scattering technique December 22, 2023 5 ICACT19-EC-70
  • 6. December 22, 2023 ICACT19-EC-70 6  Photo acoustic spectroscopy Bio impedance spectroscopy Cont…
  • 7. Biosensor • A sensor that integrates a biological element with physiochemical transducer to produce an electronic signal proportional to signal analyte which is then conveyed to detector December 22, 2023 7 ICACT19-EC-70
  • 8. Ultrasonic transducer method can be used to determine the glucose levels of human blood by studying the variation of amplitude with density of blood sample with glucose and it can be calibrated and compared to determine the sugar level. Ultrasonic Transducer Model for Biosensor December 22, 2023 8 ICACT19-EC-70
  • 9. Ultrasonic: It is a phenomenon that has the frequency above the hearing capability of human ear. • Ultrasonic transducer It is a device that converts energy into ultrasonic waveform and vice versa December 22, 2023 9 ICACT19-EC-70
  • 10. Piezoelectric materials:- • Offer a high pressure per density ratio for the actuator, • High stability in hostile environment • Chemically they are very stable. For making ultrasonic transducers and piezoelectric actuators, it is desirable to have • High electromechanical coupling coefficients • Relatively large dielectric constant • Large piezoelectric coefficient. December 22, 2023 10 ICACT19-EC-70
  • 11. Lead free Piezo Materials  Lead Zirconate Titanate (PZT) has been recognized as an environmentally non-friendly material which contains more than 60% lead by weight .  Unfortunately, among the existing lead-free ferroelectric crystals, some have weak piezoelectricity and some are very expensive to fabricate.  Different lead free piezoelectric materials like ◦ Barium Sodium Niobate (Ba2NaNb5O15)(BNN), ◦ Barium Titanate (BaTiO3)(BT) ◦ Lithium Niobate (LiNbO3) (LN) December 22, 2023 11 ICACT19-EC-70
  • 12.  Conventional ultrasonic transducer systems became very bulky and power hungry.  Hence we switched over to Micro-electro mechanical system (MEMS)  MEMS based acoustic bio-sensing transducer is based on the piezoelectric technology which exploits the nature and properties of the propagating ultrasonic wave in blood medium of various densities MEMS December 22, 2023 12 ICACT19-EC-70
  • 13. Model geometry and boundary conditions of ultrasonic transducer Fig 1: 2D axis symmetry model Fig 2:Pressure acoustics December 22, 2023 13 ICACT19-EC-70
  • 14. Piezoelectric film under stress December 22, 2023 14 ICACT19-EC-70
  • 15. 15 Acoustic pressure waveforms Fig 3: Pressure acoustic wave form Fig 4: sound acoustic waveform December 22, 2023 ICACT19-EC-70
  • 16. Acoustic pressure wave form (BNN) Fig 5: Pressure acoustic wave form of BNN Fig 6: sound acoustic waveform of BNN December 22, 2023 16 ICACT19-EC-70
  • 17. Acoustic pressure wave form (BT) Fig 7: Pressure acoustic wave form of BT Fig 8: sound acoustic waveform of BT December 22, 2023 17 ICACT19-EC-70
  • 18. Acoustic pressure wave form (LN) Fig 9: Pressure acoustic wave form of LN Fig 10: sound acoustic waveform of LN December 22, 2023 18 ICACT19-EC-70
  • 19. Acoustic pressure wave form (Zn) Fig 11: Pressure acoustic wave form of ZN Fig 12: sound acoustic waveform of ZN December 22, 2023 19 ICACT19-EC-70
  • 20. Far field polar graphs for BNN Fig 13: Far field pressure polar graph BNN Fig 14: Far field sound polar graph BNN December 22, 2023 20 ICACT19-EC-70
  • 21. Far field polar graphs BT Fig15: Far field pressure polar graph BT Fig 16:Far field sound polar graph BT December 22, 2023 21 ICACT19-EC-70
  • 22. Far field polar graphs(LN) Fig17: Far field pressure polar graph LN Fig 18:Far field sound polar graph LN December 22, 2023 22 ICACT19-EC-70
  • 23. Far field polar graphs(ZN) Fig 19:Far field pressure polar graph ZN Fig 20:Far field sound polar graph ZN December 22, 2023 23 ICACT19-EC-70
  • 24. Comparison between lead and lead-free materials 0 1 2 3 4 0 2 4 6 Zno Pzt blood sample Zno Pzt 1 3.47 3.35 2 0.8675 0.795 3 0.3855 0.2575 4 0.2168 0.1568 5 0.138 0.075 December 22, 2023 24 ICACT19-EC-70
  • 25. Blood Sample Pressure generated by LIN Pressure generated by BNN Pressure generated by BT Pressure generated by Zno 1 -255.2156377 -1564.508718 -3765.337914 -349.1934105 2 -255.2495062 -1564.715697 -3765.832407 -361.2346103 3 -255.4140098 -1565.721021 -3768.234204 -368.2795124 4 -255.590608 -1566.800254 -3770.812553 -373.2788144 5 -255.8663893 -1568.485608 -3774.838906 -377.2024183 Comparison between lead-free materials 1 2 3 4 5 Lin BNN BT Zno December 22, 2023 25 ICACT19-EC-70
  • 26. Conclusion • From the property of different lead free piezoelectric materials with different glucose concentrations of blood sample medium displacement and pressure are simulated using software COMSOL Multiphysics 5.1. • It was found that Zno has shown better performance compare to others. December 22, 2023 26 ICACT19-EC-70
  • 27. References  Pra dhan S K., Kamilla S K, Das, D P (2012), “Studies of Lead Free Piezo-Electric Materials Based Ultrasonic MEMS Model for Bio Sensor”, In Proceeding of COMSOL Conference,ISBN: 978-0-9839688-2-5. • Eun-Joo Park, Jacob Werner, Joshua Beebe, Samantha Chan, Nadine Barrie Smith, “Noninvasive Ultrasonic Glucose Sensing with Large Pigs (~200 Pounds) Using a Lightweight Cymbal Transducer Array and Biosensors” Journal of Diabetes Science and Technology, 3(3), pp-517-523, (2009). • D.W.Greve, I.J. Oppenheim, “Coupling of MEMS Ultrasonic Transducer”, Proceedings of IEEE, Sensors, (2), pp 814 – 819, (2003). • K.Miranji, Dr R sandanalakshmi., “A Technology Overview and Future Scope of Bio-Mems in Tropical Disease Detection: Review” • Tao Li, Yanhong Chen, and Jan Ma,” Development of a Miniaturized Piezoelectric Ultrasonic Transducer” IEEE Transactions on Ultrasonic's, Ferroelectrics, and Frequency Control, 56 (3), 649-659, (2009). December 22, 2023 27 ICACT19-EC-70
  • 28. December 22, 2023 ICACT19-EC-70 28 Thank You…..