1. Senology Newsletter http://www.senology.org/newsletter/Newsl_Jan2012.htm
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Editor-in-Chief: Gian Paolo Andreoletti, MD
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Literature Selection
Simoes PW et al.: "Prevalence of Human Papillomavirus in Breast Cancer: A Systematic Review",
Int J Gynecol Cancer. 2011 Dec 30. [Epub ahead of print]
Masala G et al.: "Fruit and vegetables consumption and breast cancer risk: the EPIC Italy study",
Breast Cancer Res Treat. 2012 Jan 4. [Epub ahead of print]
Raftery J et al.:"Possible net harms of breast cancer screening: updated modelling of Forrest
report", BMJ. 2011 Dec 8;343:d7627. doi: 10.1136/bmj.d7627
Scaranelo AM et al.: "Accuracy of Unenhanced MR Imaging in the Detection of Axillary Lymph Node
Metastasis: Study of Reproducibility and Reliability", Radiology 2011; Dec 5 [Epub ahead of print]
Baselga J et al.: "Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer", N
Engl J Med. 2011 Dec 7. [Epub ahead of print]
Huber C et al.: "Anti-estrogen therapy for breast cancer modifies the risk of subsequent cutaneous
melanoma", Cancer Prev Res (Phila). 2012 Jan 5; 82
Gianni L et al.: "Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with
locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised
multicentre, open-label, phase 2 trial", Lancet Oncol. 2011 Dec 6. [Epub ahead of print]
Baselga J et al.: "Everolimus in Postmenopausal Hormone-Receptor-Positive Advanced Breast
Cancer", N Engl J Med. 2011 Dec 7. [Epub ahead of print]
Hille U et al.: "Aromatase Inhibitors as Solely Treatment in Postmenopausal Breast Cancer
Patients", Breast J. 2011 Dec 16 [Epub ahead of print]
Phillips KM et al.: "Cognitive functioning after cancer treatment: A 3-year longitudinal comparison of
breast cancer survivors treated with chemotherapy or radiation and noncancer controls", Cancer.
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2. Senology Newsletter http://www.senology.org/newsletter/Newsl_Jan2012.htm
2011 Dec 12. doi: 10.1002/cncr.26432. [Epub ahead of print]
Deprez S et al.: "Longitudinal Assessment of Chemotherapy-Induced Structural Changes in Cerebral
White Matter and Its Correlation With Impaired Cognitive Functioning", J Clin Oncol. 2011 Dec 19.
[Epub ahead of print]
Nilsson G et al.: "Distribution of Coronary Artery Stenosis After Radiation for Breast Cancer", Clin
Oncol. 2011 Dec 27. [Epub ahead of print]
Bower JE et al.: "Yoga for persistent fatigue in breast cancer survivors: A randomized controlled
trial", Cancer. 2011 Dec 16 [Epub ahead of print]
Comment
"New onco-plastic surgery technique for early breast cancer", Domenico Gerbasi, Unità di Senologia,
Ospedale Bolognini, Seriate, Italy
""Recent advances of oncoplastic techniques in breast surgery have allowed to achieve maximum
oncological radicality, together with minor cosmetic alteration possible. This has resulted in an important
advantage for the patients subjected to conservative surgery for breast cancer, as proven by many scientific
studies that have highlighted in these cases a minor psychological impactl overall. The surgical technique
proposed demonstrates that, according to the conventional protocols of breast conserving therapy for cancer,
it is possible to perform a complete excision of the tumor, with an "extra-mammary" surgical approach trough
an incision made immediately below the inframammary fold, with a scar completely invisible on standing by
natural ptosis of the breast. This technique is indicated for cases of early breast cancer, regardless of the
location of the tumor, as long as there is no involvement of the overlying skin. Additional research needs to
be conducted to evaluate long term results and effectiveness of the proposed technique in relation to a large
number of cases"
(Comment on: Gerbasi D et al.: "Inframammary fold approach in breast conserving surgery for
cancer", Updates Surg. 2011 Dec;63(4):283-6)
Discussion
- Radiation Therapy for Breast Cancer: American Society of Breast Surgeons responds to San
Antonio Breast Cancer Symposium Data. What do you think? - Share your opinion on LinkedIn®
Healthcare Companies News
2011 CTRC-AACR San Antonio Breast Cancer Symposium: Positive Study Results Validating Use of
Oncotype DX(R) in DCIS Breast Cancer - Genomic Health
Calendar of Events
Implications of a multigene assay for DcIS on current treatment patterns - e-oncoreview, January 17,
2012
The World Cancer Immunotherapy Conference, January 25-26, 2012, San Diego, CA
2nd International Congress of Breast Disease Centers, February 9-10. 2012, Paris, France
Fragments of History
William S Halsted (New York, 1852-1922), "The results of radical operations for the cure of carcinoma
of the breast", Ann Surg. July 1907:46(1):1-19: “I am not sure that I have observed from breast cancer,
metastasis which seemed definitely to have been conveyed by way of the blood-vessels (…).We believe that
cancer of the breast in spreading centrifugally preserves in the main continuity with the original growth, and
before involving the viscera may become widely diffused along surface planes."
Literature Selection
Signorello LB et al.: "Congenital Anomalies in the Children of Cancer Survivors: A Report From the
Childhood Cancer Survivor Study", J Clin Oncol. 2011 Dec 12. [Epub ahead of print]
Schroeder S et al.: "Acupuncture for chemotherapy-induced peripheral neuropathy (CIPN): a pilot
study using neurography", Acupunct Med. 2011 Dec 5. [Epub ahead of print]
Rijkaart DC et al.: "Human papillomavirus testing for the detection of high-grade cervical
intraepithelial neoplasia and cancer: final results of the POBASCAM randomised controlled trial",
Lancet Oncol. 2011 Dec 14. [Epub ahead of print]
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3. Senology Newsletter http://www.senology.org/newsletter/Newsl_Jan2012.htm
Popadich A et al.:"A multicenter cohort study of total thyroidectomy and routine central lymph node
dissection for cN0 papillary thyroid cancer", Surgery. 2011 Dec;150(6):1048-57
Trinchet JC et al.: "Ultrasonographic surveillance of hepatocellular carcinoma in cirrhosis: A
randomized trial comparing 3- and 6-month periodicities", Hepatology. 2011 Dec;54(6):1987-1997
Nishikawa H et al.: "Comparison of percutaneous radiofrequency thermal ablation and surgical
resection for small hepatocellular carcinoma", BMC Gastroenterol. 2011 Dec 28;11(1):143. [Epub
ahead of print]
Simon MS et al.: "Prospective analysis of association between use of statins or other lipid-lowering
agents and colorectal cancer risk", Ann Epidemiol. 2012 Jan;22(1):17-27
Meyer RM et al.: "ABVD Alone versus Radiation-Based Therapy in Limited-Stage Hodgkin's
Lymphoma", N Engl J Med. 2011 Dec 11. [Epub ahead of print]
Jensen AO et al.: "Atopic dermatitis and risk of skin cancer: a danish nationwide cohort study
(1977-2006)", Am J Clin Dermatol. 2012 Feb 1;13(1):29-36
Barry MJ et al.: "Adverse Effects of Robotic-Assisted Laparoscopic Versus Open Retropubic Radical
Prostatectomy Among a Nationwide Random Sample of Medicare-Age Men", J Clin Oncol. 2012 Jan
3. [Epub ahead of print]
Nguyen PL et al.: "Association of androgen deprivation therapy with cardiovascular death in
patients with prostate cancer: a meta-analysis of randomized trials", JAMA. 2011 Dec
7;306(21):2359-66
Andriole GL et al.: "Prostate Cancer Screening in the Randomized Prostate, Lung, Colorectal, and
Ovarian Cancer Screening Trial: Mortality Results after 13 Years of Follow-up", J Natl Cancer Inst.
2012 Jan 6. [Epub ahead of print]
Dearnaley D et al.: "Conventional versus hypofractionated high-dose intensity-modulated
radiotherapy for prostate cancer: preliminary safety results from the CHHiP randomised controlled
trial", Lancet Oncol. 2011 Dec 12. [Epub ahead of print]
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Recent Advances in Clinical Medicine
Nathwani AC et al.: "Adenovirus-Associated Virus Vector-Mediated Gene Transfer in Hemophilia B", N
Engl J Med. 2011 Dec 10. [Epub ahead of print]
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