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Curriculum Vitae of Jagdish N. Sharma
CURRICULUM VITAE
1
JAGDISH N. SHARMA
Ph.D. (UK), D.Sc. (UK), F.C.P. (USA), F. I. Biol.,
FSB (UK), Professor
Department of Pharmacology and
Therapeutics, Faculty of Pharmacy
Health Sciences Center
Kuwait University
P.O.Box 24923, Safat 13110, Kuwait
Curriculum Vitae of Jagdish N. Sharma
CONTENTS PAGE NO
I. PERSONAL PARTICULARS AND PRESENT APPOINTMENT 3
II. ACADEMIC QUALIFICATIONS AND FELLOWSHIPS 3
III. PRESENT AND PREVIOUS ACADEMIC AND RESEARCH POSITIONS 4
IV. ADMINISTRATIVE DUTIES AS A CHAIRMAN 6
V. EDITORIAL AND ADVISORY BOARD MEMBER OF INTERNATIONAL 6
JOURNALS
VI. ADVISORY BOARD MEMBER OF INTERNATIONAL CONFERENCES 7
VII. EDITORIAL BOARD MEMBER OF NATIONAL JOURNALS 7
VIII. AWARDS AND EXTERNAL ASSESSOR FOR PROMOTION TO FULL PROFESSOR 8
AND TO THE RANK OF ASSOCIATE PROFESSOR 9
IX. MEMBERSHIP OF PROFESSIONAL LEARNED SOCIETY 9
X. POSITIONS IN INTERNATIONAL CONFERENCES 9
XI. SPECIAL INVITED GUEST LECTURES AND PLENARY LECTURE 9
XII. RESEARCH DEVELOPMENT AREAS AND RESEARCH GRANTS
Supervision of Research projects for Higher Degrees 11
Short –term University research grants 11
Long-term Research and development Grants 12
Personal Research Development 12
International Research Collaboration 12
XIII. EXAMINER OF PH.D. THESES 13
XIV. TEACHING 14
Undergraduate (M.D., M.B. Ch.B., B. Pharm. (Hons)
Nursing and Medical Technologist
Postgraduate (M.Med., M. Pharm., M.Sc., Ph.D.)
XV. BOOK AND FULL PUBLICATIONS 16
XVI. ABSTRACTS AND PRESENTATIONS IN INTERNATIONAL AND 27
NATIONAL CONFERENCES
XVII. ADVISOR AND EVALUATOR OF INTERNATIONAL RESEARCH GRANTS 34
XVIII. REFERENCES 36
2
Curriculum Vitae of Jagdish N. Sharma
I. PERSONAL PARTICULARS
Surname SHARMA
First & Middle Names JAGDISH NARAIN
Nationality Canadian
Date of Birth 15 July, 1947
Marital Status Married and having 4 children
Permanent Address 79 Stirling Crescent St. John’s
NL, A1A 4J9, Canada
T el: +1-709-754-2464
Institutional Corresponding Professor J.N. Sharma
Address Department of Pharmacology and
Therapeutics
Faculty of Pharmacy, Health Sciences Center
Kuwait University
P.O.Box 24923, Safat 13110, Kuwait
Email: j.n.sharma@hsc.edu.kw
II. ACADEMIC QUALIFICATIONS AND FELLOWSHIPS
Degree Year University and Institution Specialization
B.V.Sc. & A.H. 1970 Jawaharlal Nehru Agricultural Veterinary Medicine
(D.V.M.) University, Jabalpur, M.P. India and Surgery
M.Sc. 1973 All-India Institute of Medical Medical
Sciences, New Delhi, India Pharmacology
Ph.D. 1976 University of Strathclyde, Pharmacology
Glasgow, Scotland, UK
D.Sc. 2011 Calamus International University, Health Sciences
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Curriculum Vitae of Jagdish N. Sharma
London , UK.
F.C.P. 1995 Fellow of the American College of Clinical
Pharmacology, New York, USA
F.I.Biol. 1997 Fellow of the Institute of Biology,
London, UK
C. Biol., F.S.B. 2009 Fellow of the Society of Biology, London UK
III. PRESENT AND PREVIOUS ACADEMIC AND RESEARCH POSITIONS
Full Professor Department of Applied Therapeutics
Faculty of Pharmacy, Kuwait University, Kuwait
October 1999 – to date
Founding Chairman Department of Pharmacology and Applied Therapeutics
Faculty of Pharmacy, Kuwait University, Kuwait
January 2000 – May 2005.
Full Professor Department of Pharmacology
School of Medical Sciences and Pharmaceutical Sciences
Universiti Sains Malaysia
Penang, Malaysia
July 1991 – October 1999
Associate Professor Department of Pharmacology
School of Medical Sciences
Universiti Sains Malaysia
Penang, Malaysia
January 1987 – June 1991
Guest Professor Faculty of Pharmacy, Chiang Mai University
Chiang Mai, Thailand, June, 2006.
4
Curriculum Vitae of Jagdish N. Sharma
Visiting Professor Department of Surgery, Faculty of Medicine
Queen’s University
Kingston, Ontario, Canada
December 1991
Guest Speaker Faculty of Medicine Memorial University
St. John’s, Newfoundland, Canada
December 1991.
Senior Research Fellow/ Faculty of Medicine and Nursing
Visiting Professor Memorial University of Newfoundland
St. John’s, Newfoundland, Canada.
November 1981 – June 1983 – November 1986
Visiting Professor Department of Pharmacology
Faculty of Medicine, University of Al-Fateh
Tripoli, Libya
March 1981
Consultant / Senior Division of Pharmacology and Toxicology
Lecturer Medical School, University of Malta, Malta
September 1980 – August 1981
Lecturer Department of Pharmacology
Faculty of Medicine, University of Al-Fateh
Tripoli, Libya
March 1978 – August 1980
Visiting Research Fellow Department of Pharmacology and Physiology
University of Strathclyde
Glasgow, Scotland, U.K.
September 1978
Postdoctoral Fellow Department of Pharmacology and Physiology
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Curriculum Vitae of Jagdish N. Sharma
University of Strathclyde, Glasgow, U.K.
October 1976 – March 1978
Demonstrator Department of pharmacology and Physiology
University of Strathclyde
Glasgow, Scotland, U.K.
October 1975 – September 1976
Research Assistant / Department of Pharmacology
Teaching Fellow All- India Institute of Medical Sciences
New Delhi, India
January 1971 – September 1973
IV. ADMINISTRATIVE DUTIES AS A CHAIRMAN
1. Development of the curriculum for Applied Therapeutics and Elective courses.
2. Chairman of the Department of Applied Therapeutics of academic and technical staff
appointment committee.
3. Member of the Faculty of Pharmacy Council.
4. Member of the Dean’s Executive Committee for contributions to develop the faculty.
5. Member of the Faculty of Pharmacy selection committee for various departments.
6. Member of the Faculty of Pharmacy examination Board to monitor of the results of all the
departments.
7. Chairman of the department of Applied Therapeutics scholarship committee to select
local graduates to be trained for PhD in USA, UK or Canada.
8. Member of the Faculty of the Pharmacy promotion and renewal of contract committee for
all the departments.
9. Review and Evaluation of the Performance of Department Chairmen of the Pharmacy and
Medical Faculties.
10. Chairman of the Promotion-Revision Committee for Full Professor, Pharmacy Practice.
11.Chairman of the Selection Committee for the Chairman of Pharmaceutical Chemistry.
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Curriculum Vitae of Jagdish N. Sharma
12. Member of the distinguished teaching and research awards of the staff of the Faculty of
Pharmacy.
V-A. Honorary Advisor and Editor:
1. International Journal of Pharmacology and Pharmaceutical technology (India) from 2012 to
date
V-B. REGIONAL EDITOR FOR MIDDLE-EAST
1. Inflammopharmacology (UK) from 2006 to date.
V- C. EDITORIAL AND ADVISORY BOARD MEMBER OF INTERNATIONAL
JOURNALS
1. Agents and Actions (Inflammation Research) (Switzerland): Editorial Board Member from
1989 to 1992.
2. Experimental and Toxicologic Pathology (Formerly Experimental Pathology) (Germany):
Advisory Board member from 1989 to 1996.
3. International Journal of Tissue Reactions (Switzerland): Editorial Board member from
1994 to 2005.
4. Asia Pacific Journal of Pharmacology (Singapore): Editorial Advisory Board Member from
1995 to 2006.
5. Current Drugs Ltd. (U.K): Evaluator for the Investigational Drugs Database from
1994 to 1998.
6. Journal of Pharmacology and Toxicology, Technical Editor (Academic Journals net, USA)
from 2007 to 2009
7. Pharmacy Times (USA): Middle East Editorial Board Member from 2007 to date.
8. Inflammopharmacology (UK): Editorial Advisory Board Member from 1997 to date.
9. International Journal of Immunopathology and Pharmacology (Italy) from 2006 to 2014.
10. European Journal of Inflammation (Italy) from 2006 to date.
11. Archives of Medical Research (Mexico City) from 2006 to date.
12. Clinical Medicine: Endocrinology and Diabetes (New Zealand) from 2008 to date.
13. Clinical Medicine: Therapeutics (New Zealand) from 2009 to date.
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Curriculum Vitae of Jagdish N. Sharma
14. American Journal of Biomedical Sciences (USA) from 2009 to date.
15. Journal of Pharmaceutical Technology and Drug Research (UK) from 2011 to date.
16. Reviewer of Manuscripts for International Journals.
VI. ADVISORY BOARD MEMBER OF INTERNATIONAL CONFERENCES
1. International Kinin Conference: International Advisory Board member. Guaruja, Brazil,
1993.
2. 5th
Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunomodulators: International Advisory Board Member. Geneva, Switzerland, 1993.
3. 6th
Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunomodulators: International Advisory Board Member. Geneva, Switzerland, 1995.
4. 14th
International Symposium of Kinin: International Advisory Board Member. Denver,
U.S.A., 1995.
5. 7th
Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunomodulators: International Advisory Board Member. Geneva, Switzerland, 1997.
6. The 15th
International Conference on Kinin; International Advisory Board Member; Nara,
Japan, 1998.
7. 8th
Annual Health Sciences Poster Day, Faculty of Medicine, Kuwait University, Kuwait,
2003.
VII. EDITORIAL BOARD MEMBER OF NATIONAL JOURNALS
1. Diagnosa (The Medical Bulletin of the School of Medical Sciences, Universiti Sains Malaysia)
Editorial Committee Member from 1992 to 1993.
2. Malaysian Journal of Medical Sciences: Editorial Board Member from 1993 to 1995.
VIII. REASEARCH GRANTS, AWARDS AND EXTERNAL ASSESSOR FOR
PROMOTION TO FULL PROFESSOR
1. Research grant: Kuwait University
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Curriculum Vitae of Jagdish N. Sharma
Principal Investigator:
Clinical Priority research Grant No. PR 01/09; (Kuwait University)
entitled “ Investigational study on bradykinin system and nitric oxide in
healthy subjects, hypertensive and type -2 diabetic patients in Kuwait”. Total
amount KD 41,595.00x US$3.60 for 4 years (2011 to 2015)
Co-investigators:
1. Dr. Kamal A. S. Al-Shoumer, Associate Professor, Department of
Medicine, FoM.
2. Dr. Kamal Matar, Associate Professor, Department of Pharmacology and
Therapeutics, FoP.
3. The British Council Overseas Student Fee’s Award. October 1974 to September 1976
4. Research Fellowship awarded by the Merck, Sharp and Dohme (U.K). October 1974 to
September 1976.
5. Post-doctoral Research Fellowship awarded by the Merck, Sharp and Dohme (U.K).
October 1976 to September 1978.
6. Fellowship award from the 1st
world Conference on Clinical Pharmacology (London). June
1980.
7. Three Short –term Research Grants from Universiti Sains Malaysia, Penang, Malaysia.
September 1989 to August 1991 and April 1993 to March 1998 with the funding of M$
100000.00
8. Research And Development Grant (IRPA) Award from The Ministry of Science, technology
and Environment of Malaysia. From January 1993 with the funding of M$ 400000.00.
9. A. External Assessor for Promotion to the rank of Full Professor: Dr. Abdul Rahman H.
Mohd. Noor, MBBCh, DCH, MSc, FRCP, Vice Dean , School of Medical Sciences,
University Science Malaysia, Kubang Kerian, Kelantan, Malaysia. February 14, 2009.
B. External Assessor for Promotion to the rank of Associate Professor: Dr. Sania Abdalla
Ibrahim Shadad, PhD, Assistant Professor of Pharmacology, Faculty of Pharmacy, University
of Khartoum, Khartoum, Sudan. March 17, 2009.
C. External Assessor for Promotion to the rank of Associate Professor: Dr. Abdullah M. Al-
Mohizea, PhD, Assistant Professor, College of Pharmacy, King Saud University, Riyadh,
Saudi Arabia. February 14, 2010.
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Curriculum Vitae of Jagdish N. Sharma
D. External Assessor for Promotion to the rank of Associate Professor: Dr. Fahad Ibrahim
Abdul Rahman Al-Jenoohi, PhD, Assistant Professor, College of Pharmacy, King Saud
University, Riyadh, Saudi Arabia. 31 May, 2010.
E. External Assessor for Promotion to the rank of Full Professor: Dr. Fars Kaed Alanazi,
Associate Professor, PhD, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
27 September, 2011.
F. External Assessor for Promotion to the rank of Associate Professor: Dr Mohamed Abbas
Ibrahim Hamoud, PhD, Assistant Professor, College of Pharmacy, King Saud University,
Riyadh, Saudi Arabia. 7 June, 2012.
G. E. External Assessor for Promotion to the rank of Full Professor: Dr. Fahad Ibrahim Al-
Jenoobi, PhD, Associate Professor, College of Pharmacy, King Saudi University, Riyadh,
Saudi Arabia. April, 19, 2015.
IX. MEMBERSHIP OF PROFESSIONAL LEARNED SOCIETY
Member of the British Pharmacological Society of Great Britain.
Member of Canadian Society of Physiology and pharmacology.
Member of Canadian Society of Clinical Investigation (Canada).
Member of Malaysian Society of Pharmacology and Physiology
X. POSITIONS IN INTERNATIONAL CONFERENCES (ORAL SESSIONS)
• Chairman 26th Scientific Meeting of the Malaysia Society of Pharmacology and
Physiology. Poster Session. May 19, 2012.
• Chairman 25th
Scientific Meeting of the Malaysia Society of Pharmacology and
Physiology. Symposia on Tissue Engineering. May 26, 2011.
• Chairman 15th
International Conference on Kinins. October 19 – 24, 1998.
Nara, Japan.
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Curriculum Vitae of Jagdish N. Sharma
• Chairman 7th
Intersciences World Conference on Inflammation,
Antirheumatics, Analgesics, Immunomodulators. May 19 – 21, 1997.
Geneva, Switzerland.
• Chairman 6th
Intersciences World Conference on Inflammation,
Antirheumatics, Analgesics, Immunomodulators, March 28 – 30, 1995.
Geneva, Switzerland.
• Chairman Kinin International Congress. October 17 – 22, 1993. Guaruja,
Brazil.
• Chairman 5th
Intersciences World Conference on Inflammation,
Antirheumatics, Analgesic, Immunomodulators. April 25 – 28, 1993.
Geneva, Switzerland.
• Chairman The International Conference on the Use of Traditional
Medicine and Other Natural Products in Health-Care. June 8 – 11, 1993.
Geneva, Switzerland.
• Chairman Kinin International Conference Towards Understanding the
Molecular Basis of Kinin Actions. September 8 – 14, 1991. Munich,
Germany.
• Chairman 4th
Intersciences World Conference on Inflammation,
Antirheumatics, Analgesics, Immunomodulators. April 15 – 18, 1991.
Geneva, Switzerland.
• Chairman 3rd
Intersciences World Conference on Inflammation,
Antirheumatics, Analgesics, Immunomodulators. March 15 – 18, 1989.
Monte Carlo
• Chairman Kinin International Conference, November 29 – December 3,
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Curriculum Vitae of Jagdish N. Sharma
1987. Tokyo, Japan
XI. SPECIAL INVITED GUEST LECTURES AND PLENARY LECTURE
1. Department of Pharmacology, All- India Institute of Medical Sciences, New Delhi, India, July
1980.
Lecture: “The Kallikrein –Kinin System”.
2. Symposium on Renal function, Hypertension and Kallikrein-Kinin System: Satellite
Symposium of International Kinin Conference, Sapporo, Japan, December 1987.
Lecture: “the Kallikrein- Kinin System and Hypertension”.
3. Department of Pharmacology, All –India Institute of medical Sciences, New Delhi, India, May
1989.
Lecture: “Involvement of Kinin in the Action of Angiotensin Converting Enzyme Inhibitors”.
4. 8th
Scientific meeting of the Malaysian Society of Pharmacology and Physiology, Penang,
Malaysia, July 1989.
Lecture: “ The Kinin System in Hypertension and Inflammation”
5. International Kinin Conference, Munich, Germany. September 1991.
Lecture: “Involvement of the Kinin –Forming System in the Genesis of Joint Inflammatory
Disease”.
6. Department of Surgery, Queen’s University Medical School, Kingston, Ontario, Canada,
December1991.
Lecture: “The Role of Kallikrein - Kinin System in the Genesis of Joint Inflammatory
Disease”
7. Division of Basic Medical Sciences, Faculty of Medicine, Memorial University of
Newfoundland, St. John’s, Canada, December 1991.
Lecture: “The Kallikrein – Kinin System in Blood Pressure Regulation”.
8. School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia,
May 1992.
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Curriculum Vitae of Jagdish N. Sharma
Professorial Public Lecture: “Significance of Bradykinin in Health and Disease”.
9. 11th
Iranian Congress of Physiology and Pharmacology, Tabriz University of Medical
Sciences, Tabriz, Iran, May 1993.
Lecture: “The Role of Kallikrein- Kinin System in Hypertensive Disease”.
10. 7th
Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunomodulators, Geneva, Switzerland, May 1997.
Lecture: “Cardioprotective Effects of Kinin System and its Role in Inflammation”
11. Postgraduate Seminar in Cardiovascular Therapeutics, Universiti Sains Malaysia, Penang,
Malaysia, November 1997.
Lecture: “Significance of Kallikrein- Kinin System in Hypertension”.
12. International Conference of Stress, Prophylaxis and Treatment, Calcutta, India, January
1998.
Lecture: “Kallikrein – KininSystem in Hypertension and Diabetes”.
13. Asthma in the 1990s: Current Insights and Future Outlook, Penang, Malaysia, October 1998.
Lecture: “Inflammatory Mediators in Asthma”
14. Rheumatology update symposium, Faculty of Medicine, Kuwait University, Kuwait, January
2001.
Lecture: “Drugs used in Patients with Common Rheumatic Diseases”.
15. International Conference on Inflammopharmcology 2003, Royal College of Physicians of
Edinburgh, Scotland. April 2003.
Lecture: “Recent advances in the kallikrein-kinin system in inflammatory disorders”.
16. 7th
International Symposium on Pharmaceutical Sciences, Ankara University Faculty of
Pharmacy, Ankara, Turkey, June 2003.
Lecture: “Significance of the kinin system in the cardiovascular disorders.
17. The Philippines Society of Experimental and Clinical Pharmacology Meeting, Faculty of
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Curriculum Vitae of Jagdish N. Sharma
Medicine and Surgery, Department of Pharmacology, University of Santo Tomas, Manila,
Philippines, May 2004.
Lecture: “The kallikrein-kinin system in cardiovascular disorders- a new therapeutics
modality found?
18. 20th
Federation of the Asian Pharmaceutical Association Congress, Bangkok, Thailand,
November 30 – December 3, 2004.
Lecture: “Bradykinin agonists in the treatment of cardiovascular disorders”.
19. 20th
Scientific meeting of the Malaysian Society of Pharmacology and Physiology, Penang,
Malaysia, April 25-29, 2005.
Plenary lecture: “The role of nutraceuticals in therapeutics: myth or reality.
20. Faculty of Pharmacy, Chiang Mai University, Thailand, June 11-14, 2006.
Guest lectures: Important roles of the kinin-forming components in cardiovascular and
inflammatory conditions, and the role of nutraceuticals in therapeutics: myth or reality.
21. 4th
Asian Association of Schools of Pharmacy and 9th
Malaysian Pharmaceutical Society
Pharmacy Scientific Conference 2009 , Penang, Malaysia, June 10-13, 2009.
Invited Lecture: “Role of the bradykinin system in hypertension: Prospects for future drug
Therapy.
22. 24th
Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Shah
Alam, Kuala Lumpur, Malaysia, June 2-3, 2010.
Special Lecture: Bradykinin system and rheumatoid arthritis: An overview.
23. 25th
Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Serdang,
Selangore, Malaysia, May 25 - 26, 2011.
Plenary Lecture: Kallikrein-kinin pathway in cardiovascular and renal systems: possibility for
new drug development.
24. 26th
Scientific Meeting of the Malaysian Society of Pharmacology and Physiology,
Penang, Malaysia, May 18 - 20, 2012.
Plenary Lecture: Bradykinin system: Role in hypertension and diabete.
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Curriculum Vitae of Jagdish N. Sharma
25. 27th
Scientific Meeting of the Malaysian Society of Pharmacology and Physiology,
Kuantan, Malaysia, September 6 - 8, 2013.
Plenary Lecture: Kallikrein-kinin pathways in cardio-renal system: prospect of new drug
development.
XII. RESEARCH AND DEVELOPMENT AREAS
Supervision of Research Projects for Higher Degrees
1. Ph.D. (Doctor of Medical Science) under the Japanese Society for Promotion of
Science.
Research work on the “The role of Kallikrein – Kinin System in Experimental
Hypertension”.
Candidate’s name: S.S.J. Mohsin, B.Sc,. M.Sc. (Australia), Associate
Professor and Ex-Head of Pharmacology, School of Medical Sciences,
Universiti of Sains Malaysia. The degree was awarded in March 1992
from the Kitasato University School of Medicine, Kanagawa, Japan.
2. M.Sc. By Research work on “Pharmacological Studies of Some Mediators on
Guinea –Pig Tracheal Smooth Muscle”.
Candidate’s Name: Dr. Akbar Ali, M.B.B.S. (Rangoon). Completed in 1994.
3. M.Sc. By Research work on “The studies on Kallikrein –Kinin System in Normotensive and
Hypertensive Rats with and without Diabetes”.
Candidate’s Name: Dr. K. Uma, M.B.B.S. (Madras). Completed in 1995.
4. M.Sc. By Research work on “Role of the Kallikrein System in Cardiac Arrhythmias induced
by Coronary Artery Ligation in Rats”.
Candidate’s name: S. Atif Abbas, B.Pharm. (Pakistan). Completed in 1999.
5. M.Sc. By Research work on “Anti-Inflammatory Activity of the Fractinated Extract of Plant
Crinum Asiaticum (Family: Amaryllidacene)”.
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Curriculum Vitae of Jagdish N. Sharma
Candidate’s name: A. Mabruk Samud, B.Pharm. (Libya). Completed in 1998.
Short – Term University Research Grants (1989 – 1991 and 1993 – 1994 – 1998)
1. Role of Kinin System in experimental arthritis
2. Role of Kinin System in experimental hypertension.
3. Involvement of Kallikrein – Kinin System in experimental epilepsy.
Long – Term Research Development Grant from the Ministry of Science, Technology and
Environment Malaysia
1. Investigations on the role of humoral factors with the emphasis on the Kallikrein – Kinin
System experimental models (1993 – 1995).
a. Hypertension
b. Inflammatory Joint disease
c. Asthma
2. Studies on cardiac and renal Kallikrein –Kinin System in Hypertension (1997 – 1999).
Personal Research and Development
1. Critical evaluations of the molecular actions of Kallikreins–Kininogens-Kinins–Kininases
System and its interactions with arachidonic acid products, platelet activating factor,
cytokines and products released by endothelial cells in experimental hypertension,
inflammation, asthma and diabetes.
2. Contributions of the Kallikreins-Kininogens-Kinins-Kininases and related agents in the
pathophysiology of inflammation and cardiovascular-renal disorders with special reference
to hypertension and diabetes.
3. Evaluations of the mode of actions of antihypertensive agents dependant upon the Kallikrein
– Kinin System.
4. Mechanism of actions and toxicity of anti-inflammatory agents with reference of
cardiovascular, gastrointestinal, renal and airway systems.
5. Blood pressure regulation by the Kallikrein-Kinin System, and its role in the pathophysiology
of left ventricular hypertrophy in the presence of hypertension.
6. Endogenous agents in regulation of tracheal smooth muscle in experimental and clinical
asthma.
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Curriculum Vitae of Jagdish N. Sharma
7. Kallikrein – Kinin System in experimental and clinical diabetes.
International Research Collaboration
1. Professor M. Katori, Department of Pharmacology, Kitasato University, School of Medicine,
Kitasato, Kanagawa, Japan.
2. Professor J.M. Stewart, Department of Biochemistry, School of Medicine, University of
Colorado, Health Sciences Center, Denver, U.S.A.
3. Associate Professor K.C. Srivastava, Department of Environmental Medicine Institute of
Community Health, Odense University, Odense, Denmark.
4. Dr. K. Wirth, Hoechst AG, SBU Cardiovascular Agents, Frankfurt (Main), Germany.
5. Professor E.K. Gan, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang,
Malaysia.
XIII. EXAMINER FOR PH.D. THESES
1. Ph.D. Theses Examiner, Department of Pharmacology, Faculty of Medicine, National
University of Malaysia, Kuala Lampur, Malaysia. January 1992.
2. Ph.D. Thesis Examiner, Department of Pharmacology, Faculty of Medicine, National
University of Malaysia, Kuala Lumpur, Malaysia. February 1994.
XIV. TEACHING
Undergraduate (M.D., M.B.Ch.B. and B.Pharm (Hons)).
1. Problem Based Learning and Fixed Modules learning to 2nd
and 3rd
year M.D. and B.
Pharm. (Hons) students in the Integrated System of Education.
2. A course of lectures and tutorials on Physiological and Pharmacological Basis of
Therapeutics to 1st
, 2nd
, and 3rd
year, 4th
year and 5th
year M.D. and B.Pharm.
3. Problem coordinator for Respiratory Block and Coordinator for Central Nervous System
to M.D. and B. Pharm.
4. Practical classes on pharmacological experiments.
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Curriculum Vitae of Jagdish N. Sharma
5. Elective topics on non-medical curriculum related subjects and research elective on
Advanced Therapeutics for M.D. and B.Pharm. Courses.
6. Pharmacological Basis of Therapeutics of Renal, Respiratory, Blood, Cardiovascular,
Central Nervous System, Gastrointestinal System, Autacoids Pharmacology, General
Pharmacology, Anti-Microbial, Endocrine Pharmacology, Autonomic Pharmacology,
Dermatology and Rheumatology
7. Course coordinator of Applied Therapeutics courses of B. Pharm. Pharmacy programs
432, 531 and 533.
8. Patients Case Based Teaching of Applied Therapeutics to B.Pharm. 432 and 533.
9. Pathophysiology and Chemotherapeutics to B.Pharm.
Nursing and Medical Technologists
1. Course of lectures on Pharmacology.
2. Practical classes in experimental pharmacology.
Postgraduate
1. Co-coordinator of the Department of Pharmacology to 1st
year M.Med. (Master of
Medicine) students in Internal Medical, Pediatrics and Surgical Base Disciplines.
September 1988 – 1996.
2. Board Member of the Postgraduate Research and Development Committee of the School
of Medical Sciences, Universiti Sains Malaysia. July 1988 – 1996.
3. Lectures or courses of lectures to Master of Medicine and Master of Pharmacy students
in Medical and Surgical Base Departments.
4. Chairman of the Continuity Medical Education, School of Medical Sciences, Universiti
Sains Malaysia. February 1995 to Dec 1996.
5. Supervision of Ph.D. and M.Sc. research projects.
18
Curriculum Vitae of Jagdish N. Sharma
XV- A. BOOK:
1. Jagdish N. Sharma (2011). “Topics in Mediators Pharmacology” 1st
Edition, Nova Science
Publishers, Inc., New York, USA
2. Jagdish N. Sharma (2014). Progress in Drug Research: Recent Developments in the
Regulation of Kinins (Editor). Volume 69. Editor. Springer International Publisher, Basel,
Switzerland.
XV-B. FULL PUBLICATIONS:
109. Sharma , J. N. and Narayanan, P. ( 2015 ). Basic pharmacology of bradykinin
receptor agonists. Austin Journal of Pharmacology and Therapeutics (USA) 3: 1070
108. Sharma, J. N. , Al-Shoumer, K. A. S., Matar, Madathil, N. V. and Al-Moalem, A.M.K. ( 2015 ).
Altered activities of kininsae II, an angiotensin converting enzyme, prekallikrein
and nitric oxide in Kuwaiti patients with type 2 diabetes. International Journal of
Immunopathology and Pharmacology (Italy) 28: 240-246.
107. Sharma, J. N. (2014). Basic and clinical aspects of bradykinin receptor
antagonists. In “ Progress in Drug Research: Recent Developments in the Regulation of
Kinins. Volume 69. Edited by J. N. Sharma, Springer International Publisher, Basel,
Switzerland. pp. 1-14.
106. Sharma, J. N. and Narayanan, P. (2014). The kallikrein-kinin pathways in
hypertension and diabetes.. In “ Progress in Drug Research: Recent Developments in the
Regulation of Kinins. Volume 69. Edited by J. N. Sharma, Springer International Publisher,
Basel, Switzerland, pp.15-36.
105. Sharma, J. N. , Al-Shoumer, K. A. S., Matar, K. M., Al-Gharee, H. Y. and Madathil, N. V.
(2013). Bradykinin-forming components in Kuwaiti patients with type 2 diabetes.
International Journal of Immunopathology and Pharmacology (Italy) 26: 699-705
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Curriculum Vitae of Jagdish N. Sharma
104. Sharma, J. N. (2013). The kinin system in hypertensive pathophysiology.
Inflammopharmacology (UK) 21: 1-9
103. Sharma, J. N. (2012). Association between the kinin-forming system and
cardiovascular pathophysiology. Asia Pacific Journal of Tropical Biomedicine (China)
2 (Supplement 3): S1938-S1944.
102. Sharma, J. N. and Al-Banoon, A. (2012). The role of inflammatory mediator brabykinin in
cardiovascular and renal system. Open Access Scientific Report. 1: 142.doi:104172
101. Sharma, J. N. and Narayanan, P. (2011). Hypertension and Diabetes: Contribution
of the kallikrein-kinin system. Journal of Diabetes and Metabolism (USA) S4:004.
doi:10.4172/2155- 6156. S4-004.
100. Sharma, J. N. and Kesavarao, U. (2011). The effects of captopril on cardiac
regression, blood pressure and bradykinin components in diabetic Wistar Kyoto rats.
International Journal of Immunopathology and Pharmacology (Italy) 24: 337-343.
99. Sharma, J. N. and Al-Sherif, G. J. (2011). The kinin system: present and future
pharmacological targets. American Journal of Biomedical Sciences (USA) 3: 156-169.
98. Sharma, J. N. (2010). Activation of bradykinin system by angiotensin- converting
enzyme inhibitors. European Journal of Inflammation (Italy) 8: 55-61.
97. Sharma, J. N. (2010). Modification in tissue kallikrein activity with indomethacin
and prednisolone treatment in arthritic rats. Inflammopharmacology (UK) 18: 113-117.
96. Sharma, J. N. (2009). An overview on relation between the bradykinin system and
hypertension and diabetes. American Journal of Biomedical Sciences (USA) 1: 242-249.
95. Sharma, J. N. (2009). Hypertension and the bradykinin system. Current
Hypertension Reports (USA) 11: 178-181.
94. Sharma , J. N. (2009). The kallikrein-kinin pathways in mediating the
20
Curriculum Vitae of Jagdish N. Sharma
hypotensive action of angiotensin converting enzyme (ACE) inhibitors. In “ Angiotensin
Converting Enzyme Inhibitors” Edited by A. N. DeBrue. Nova Science Publishers (USA)
pp. 185-198.
93 Sharma, J. N. (2008). Cardiovascular activities of the bradykinin system.
The Scientific World Journal (USA) 8: 384-393.
92. Sharma, J. N., Kadir, Z. and Uma, K. (2008). Evaluation of inflammatory kinin-forming
components in experimental epilepsy in rats. Inflammopharmacology (UK) 16: 151-153.
91. Sharma, J. N. (2007). The bradykinin system: role in cardiovascular and
and diabetic pathophysiology. Current Topics in Pharmacology (India) 11: 91-100.
90. Sharma, J. N., Al-Omran, A and Parvathy, S. S. (2007). Role of nitric oxide in
inflammatory diseases. Inflammopharmacology (U.K.) 15: 252-259
89. Sharma, J. N. and Kesavarao, U. (2007). Changes in plasma prekallikrein activity,
blood pressure and left ventricular thickness in hypertensive and normotensive diabetic
rats. Methods and Findings in Experimental and Clinical Pharmacology (Spain) 29: 75-
78.
88. Sharma, J. N. (2007). The kinin-forming system and cardiovascular disorders. Journal
Salud (i) Ciencia (Argentina) 15: 972-976.
87 . Sharma, J. N. and Al-Sherif, G. J. (2006). Pharmacologic targets and prototype
therapeutics in the kallikrein-kinin system: Bradykinin receptor agonists or antagonists.
The Scientific World Journal (USA) 6: 1247-1267.
86 Sharma, J. N. and Abbas, S. A. (2006). Effect of captopril in the presence of
Kinin B2-receptor antagonist on the duration of survival after prolonged coronary
artery ligation in hypertensive rats. Methods and Findings in Experimental and
Clinical Pharmacology (Spain) 28: 217-221.
85 Sharma, J. N. (2006). Is there a place for bradykinin agonists in therapy of
21
Curriculum Vitae of Jagdish N. Sharma
cardiovascular disorders? Journal of Pharmacology and Toxicology (USA)
1: 12-18.
84 Sharma, J. N. and Mohammed, L. A. (2006). The role of leukotrienes in
pathophysiology of inflammatory disorders: Is there a case for revisiting
leukotrienes as therapeutic targets? Inflammopharmacology (UK) 14: 10-16.
83 Sharma, J. N. (2006). Role of tissue kallikrein-kininogen-kinin pathways in
cardiovascular system. Archives of Medical Research (USA) 37: 299-306
.
82 Sharma, J. N. and Jawad, N. M. (2005). Adverse effects of COX-2 inhibitors.
The Scientific World Journal (USA) 5: 629-645.
81 Sharma, J. N. and Abbas, S. A. (2005). A bradykinin antagonist abolishes
beneficial effect of captorpril on duration of survival after acute coronary artery
ligation in hypertensive rats. Pharmacological Research (UK) 52: 211-215.
80 Sharma, J. N. (2005). The kallikrein-kinin system: From mediator of inflammation to
modulator of cardioprotection. Inflammopharmacology (UK) 12: 591-596.
79 Sharma, J. N. and Thani R. B. (2004). Therapeutic prospects of bradykinin receptor
agonists in the treatment of cardiovascular diseases. Investigational Drugs Journal
(IDrugs) (UK) 7: 926-934
78 Sharma, J. N. (2004). Bradykinin agonists in the treatment of cardiovascular disorders.
In the “Proceeding of the 20th
Federation of the Asian Pharmaceutical Association
(FAPA) Congress; Edited by Srianujata, S.; Bangkok, Thailand. pp 1-6.
77 Sharma, J. N., Samud, A. M. and Asmawi, M. Z. (2004). Comparison between
plethysmometer and micrometer methods to measure acute paw oedema for scrining
ant-inflammatory activity in mice. Inflammopharmacology (UK) 12: 89-94
76 Sharma, J. N., Abbas, S. A., Yusof, A. P. M., Shah, R. P. and Gan, E. K. (2004). Tissue
kallikrein increases survival after prolonged coronary artery ligation in hypertensive
rats. Pharmacology (Basel) 70: 201-205
22
Curriculum Vitae of Jagdish N. Sharma
75 Sharma, J. N. (2003). Does the kinin system mediate in cardiovascular abnormalities?
An overview. The Journal of Clinical Pharmacology (USA) 43: 1187-1195.
74 Sharma, J. N. and Al-Dhalmawi, G. (2003). Bradykinin receptor antagonists: therapeutic
implications. Investigational Drugs Journal (IDrugs) (UK) 6: 581-586.
73 Sharma, J. N., Abbas, S. A., Yusof, A. P. M. and Shah, R. P. (2003). Evaluation of tissue
kallikrein activity on survival time after acute coronary artery ligation in hypertensive
rats. International Immunopharmacology (USA) 3: 329-334.
72 Sharma, J. N. and Uma, K. (2002). Effect of Captopril on Urinary Kallikrein, Blood
Pressure and Myocardial Hypertrophy in Diabetic Spontaneously Hypertensive Rats.
Pharmacology (Basel) 64: 196- 200.
71 Sharma, J. N. and Sharma, J. (2002). Cardiovascular Properties of the Kallikrien- Kinin
System. Current Medical Research and Opinion (Lond.) 18: 10- 17.
70 Sharma, J. N., Zubaid, M., Khan, B. Z. S. J., Yusof, A.P.M. and Asmawi, M. Z. (2000).
Pathophysiological activities of the Kallikrien- Kinin System with emphasis on the
cardiovascular disorders. Inflammopharmacology (UK) 8: 219- 241.
69 Sharma, J. N. (2000). Kinin System in Protecting the Heart. In “National Symposium on
Health Sciences Proceeding”, Edited by K.L. Yap et al. Kuala Lumpur, Malaysia. PP.
381- 384.
68 Sharma, J. N., Kesavarao, U. and Yusof, A.P.M. (1999). Altered Cardiac Tissue and
Plasma Kininogen levels in Hypertensive and Diabetic Rats. Immunopharmacology 43:
129- 132.
67 Abbas, S.A., Sharma, J.N. and Yusof, A.P.M. (1999). The Effect of Bradykinin and Its
Antagonist on Survival Time After Coronary Artery Occlusion in Hypertensive Rats.
Immunopharmacology (The Netherlands). 44: 93 – 98.
66 Samud, A.M., Asmawi, M.Z., Sharma, J.N. and Yusof, A.P.M. (1999). Anti-inflammatory
Activity of Cranum Asiaticum Plant and Its Effect on Bradykinin Induced Contractions
on Isolated Uterus. Immunopharmacology. (The Netherlands). 43: 311 – 316.
23
Curriculum Vitae of Jagdish N. Sharma
65 Abbas, S.A., Sharma, J.N. and Yusof, A.P.M. (1999). Effect of Bradykinin and Its
Antagonist on Survival Time After Coronary Artery Occlusion in Rats. General
Pharmacology (USA). 33: 243 – 247.
64 Sharma, J.N. and Yusof, A.P.M. (1998). Proinflammatory Properties of the Kallikrein –
Kinin System: Potential for new Drugs Therapy. Inflammopharmacology (The
Netherlands) 6: 286 – 296.
63 Akbar, A., Sharma, J.N., Yusof, A.P.M. and Gan, E.K. (1998). Potentiation of Bradykinin
Induced Responses by Indomethacin in Intact and Denuded Epithelium of Guinea-Pig
Tracheal Preparations. International Journal of Tissue Reactions (Geneva). XX: 95 –
100.
62 Sharma, J.N., Uma, K. and Yusof, A.P.M. (1998). Left Ventricular Hypertrophy and Its
Relation to Cardiac Kinin-Forming System in Hypertensive and Diabetic rats.
International Journal of Cardiology (U.K.) 63: 229 – 235.
61 Sharma, J.N., Yusof, A.P.M. and Wirth, K.J. (1998). The Kinin antagonist Hoe 140
Reduces Paw Oedema in rats Caused by Carrageenan, Bradykinin and Kaolin.
Inflammopharmacology (The Netherlands) 6: 9 – 17.
60 Sharma, J.N., Yusof, A.P.M. and Ishak, F.I. (1997). Significance of the Kinin System in
Pathophysiology of Inflammatory Joint Diseases. In “Proceedings of the 16th
Asian
Congress of Pharmaceutical Sciences”. Edited by Hussin, A.H., Ibrahim, M.I.M. and
Awang, R. Malaysian Pharmaceutical Society, Kuala Lumpur, pp. 140 – 145.
59 Sharma, J.N., Ishak, F.I., Yusof, A.P.M. and Srivastava, K.C. (1997). Effects of Eugenol
and Ginger Oil on Adjuvant Arthritis and the Kallikrein in Rats. Asia Pacific Journal of
Pharmacology (Singapore) 12: 9 – 14.
58 Sharma, J.N. and Yusof, A.P.M. (1997). Cardioprotective Effects of Kinin System and its
role in Inflammation. International Journal of Tissue Reactions (Geneva) 19: 53.
57 Sharma, J.N. and Kesavarao, U. (1996). Cardiac Kallikrien in Hypertensive and
Normotensive Rats with and without Diabetes. Immunopharmacology (The
Netherlands) 33: 341 – 343.
24
Curriculum Vitae of Jagdish N. Sharma
56 Sharma, J.N. and Wirth, K.J. (1996). Inhibition of rats Adjuvant Arthritis by a Bradykinin
Antagonist Hoe 140 and its Influence on Kallikrein. General Pharmacology (U.S.A.) 27:
133 – 136.
55 Sharma, J.N., Uma, K., Noor, A.R. and Rahman, A.R. (1996). Blood Pressure Regulation
by the Kallikrein-Kinin System. General Pharmacology (U.S.A.) 27: 55 – 65.
54 Sharma, J.N., Amrah, S.S. and Noor, A.R. (1995). Suppression of Hypotensive
Responses of Captopril and Enalapril by kallikrein Inhibitor Aprotinin in Spontaneously
Hypertensive Rats. Pharmacology (Basel) 50: 363 – 369.
53 Sharma, J.N., Srivastava, K.C. and Gan, E.K. (1994). Suppressive Effects of Eugenol and
Ginger Oil on Arthritic Rats. Pharmacology (Basel) 49: 314 – 318.
52 Sharma, J.N., Amrah, S.S. and Srivastava, K.C. (1994). Anti-inflammatory Properties of
Eugenol and Ginger Oil in Rat Arthritis Induced by Mycobacterial Adjuvant. In “Trends
in Traditional Medicine Research”. Edited by Chan, K.L., Hussin, A.H., Yuen, K.H.,
Asmawi, M.Z. and Ismail, Z., School of Pharmaceutical Sciences, Universiti Sains
Malaysia, Penang, Malaysia. pp.298 – 302.
51 Sharma, J.N. and Buchanan, W.W. (1994). Pathogenic Responses of Bradykinin System
in Chronic Inflammatory Rheumatoid Disease. Experimental and Toxicologic Pathology
(Germany) 46: 421 – 433.
50 Sharma, J.N. (1993). Therapeutic Prospects of Bradykinin Receptor Antagonists.
General Pharmacology (Lond.) 24: 267 – 274.
49 Sharma, J.N., Stewart, J.M., Mohsin, S.S.J., Katori, M. and Vavrek, R. (1992). Influence of a
Kinin Antagionist on Acute Hypotensive Responses Induced by Bradykinin and
Captopril in Spontaneously Hypertensive Rats. Agents and Actions 38 (Suppl.III): 258 –
269.
48 Sharma, J.N. (1992). Involvement of the Kinin – Forming System in the
Physiopathology of Rheumatoid Inflammation. Agents and Actions 38 (Suppl. III): 343 –
361.
25
Curriculum Vitae of Jagdish N. Sharma
47 Mohsin, S.S.J, Majima, M., katori, M. and Sharma, J.N. (1992). Important Suppressive
Roles of the kallikrein – Kinin System During the Developmental Stage of Hypertension
in the Spontaneously Hypertensive Rats. Asia Pacific Journal of Pharmacology
(Singapore) 7: 73 – 82.
46 Akbar, A. and Sharma, J.N. (1992). Influence of Indomethacin on Histamine –and-
Acetylcholine- Induced Responses in the Intact and Denuded Epithelium of Guinea –
Pig Tracheal Smooth Muscle. Pharmacological Research (Lond.). 25: 279 – 286.
45 Sharma, J.N. (1991). Pro-Inflammatory Actions of Platelet Activating Factor: Relevant
to Joint Inflammatory disease. Experimental Pathology (Jena) 43: 47 – 50.
44 Sharma, J.N. (1991). The Role of Kinin System in Joint Inflammatory Disease.
European Journal of Rheumatology and Inflammation (Lond.) 11: 30 – 36.
43 Sharma, J.N. (1991). The Role of Kallikrein –Kinin System in Joint Inflammatory
Disease. Pharmacological Research (Lond.) 23: 105 – 112.
42 Sharma, J.N. (1990). Does Kinin Mediate the Hypotensive Action of Angiotensin
Converting Enzyme (ACE) Inhibitors? General Pharmacology (Lond.) 21: 451 – 457.
41 Sharma, J.N. and Mohsin, S.S.J. (1990). The Role of Chemical mediators in
Pathogenesis of Inflammation with Emphasis on the Kinin System. Experimental
Pathology (Jena) 38: 73 – 96.
40 Sharma, J.N. (1989). Contribution of Kinin System to the Antihypertensive Action of
Angiotensin Converting Enzyme Inhibitors. Advances in Experimental Medicine and
Biology (New York) 247A: 197 – 205.
39 Sharma, J.N. (1988). The Kinin System and Prostaglandins in the Intestine.
Pharmacology and Toxicology (Acta Pharmacologica et Toxicologica) (Copenhagen)
63: 310 – 316.
38 Sharma, J.N., Zeitliln, I.J., Mackenzie, J.F. and Russell, R.I. (1988). Plasma Kinin –
Precursor levels in Clinical Intestinal Inflammation. Fundamental and Clinical
Pharmacology (Paris) 2: 399 – 403.
26
Curriculum Vitae of Jagdish N. Sharma
37 Sharma, J.N., (1988). The Kallikrein –Kinin System and Hypertension in “Renal
Function, Hypertension and Kallikrein – Kinin System”. Edited by limura, O. and
Margolius, H.S. University of Tokyo Press, Tokyo, pp. 147 – 154.
36 Sharma, J.N. (1988). Interrelationship Between the Kallikrein-Kinin System and
Hypertension. A review, General Pharmacology (Lond.)19: 177 – 187.
35 Alhaboui, H.A., Bennett, D., Sharma, J.N., Thomas, G.R. and Zeitliln, I.J. (1986). A Synovial
Amidase Acting on Tissue Kallikrein- Selective Substrate in Clinical and Experimental
Arthritis. Advances in Experimental Medicine and Biology (New York) 198B: 405 – 411.
34 Sharma, J.N. (1986). Kallilkrein – Kinin System and Prostaglandin Interactions:
Relevant to hypertension. Pharmacological Research Communications (Lond.) 18: 639
– 652.
33 Sharma, J.N. (1984). Kinin –forming System in the Genesis of Hypertension. Agents
and Actions (Basel) 14: 200 – 205.
32 Sharma, J.N., Fernandez, P.G. and Triggle, C.R. (1984). The Effect of Indomethacin on
the duration of Hypotensive Action of Bradykinin in Dahl Salt – Resistant Rats: Role of
cyclo-oxygenase inhibition. Prostaglandins Leukotrienes and Medicine (Edinburgh) 14:
131 – 135.
31 Sharma, J.N., Fernandez, P.G., Laher I. And Triggle C.R. (1984). Differential Sensitivity of
Dahl Salt – Sensitivity and Salt – Resistant rats to the Hypotensive Action of Acute
Nifedipine Administration. Canadian Journal of Physiology and Pharmacology 62: 241
– 243.
30 Sharma, J.N., Fernandez, P.G., Kim, B.K. and Triggle, C.R. (1984). Systolic Blood
pressure Responses to Enalapril Maleate (MK – 421), an angiotensin converting enzyme
inhibitor and Hydrochlorothiazide in Conscious Dahl Salt Sensitive (S) and Resistant
(R) Rats. Canadian Journal of Physiology and Pharmacology 62:846 – 849.
29 Sharma, J.N. (1983). Ability of Prostaglandins to induce Acute Inflammatory Bowel
Disease in the Rats. A preliminary report. Journal of Medicine (New York) 14: 157 –
160.
27
Curriculum Vitae of Jagdish N. Sharma
28 Fernandez, P.G., Kim, B.K., Galway, A.B. and Sharma, J.N. (1983). Separation of Essential
Hypertensive Patients based on Blood Pressure Responses after the withdrawal of
Antihypertensive Agent by Stepwise Discriminent Analysis. Current Medical Research
and Opinion (Lond.) 8: 509 – 517.
27 Sharma, J.N., Fernandez, P.G., Kim, B.K., Edikio, H. and Triggle, C.R. (1983). Cardiac
Regression and Blood pressure Control in the Dahl Rat Treated with Enalapril Maleate
(MK – 421), an angiotensin converting enzyme. Journal of Hypertension (Lond.) 1: 251
– 256.
26 Sharma, J.N., Zeitlin, I.J., Deodhar, S.D. and Buchanan, W.W. (1983). Detection of
Kallikrein-Like Activity in Inflamed Synovial Tissue. Archives Internationales de
Pharmacodynamie et de Therapie (Ghent) 262: 279 – 286.
25 Fernandez, P.G., Sharma, J.N., Galway, A.B., Campbell, N., Kim, B.K., Snedden, W.,
Granter, S., MacDonald, J. and Gill, V. (1982). Potassium Conservation with Amiloride
Hydrochlorothiazide (Modurate) in Thiazide Induced Hypokalemia in Hypertension.
Current Medical Research and Opinion (Lond.) 8: 120 – 127.
24 Snedden, W., Sharma, J.N. and Fernandez, P.G. (1982). A sensitive Assay Method of
Furosemide in Plasma and Urine by High-Performance Liquid Chromatography.
Therapeutic Drug Monitoring (New York) 4: 831 – 383
23 Fernandez, P.G., Sharma, J.N., Gallway, A.B., Kim, B.K., Granter, S. and Zachariah, P.K.
(1982). Comparison of Antihypertensive Efficacy: Propanolol Verses Oxprenolol in
Accelerated Hypertension. Pharmatherapeutica (Lond.) 3: 153 – 156.
22 Sharma, J.N. and Fernandez, P.G. (1982). Pharmacological Abnormality of the
Kallikrein-Kinin System in Hypertension. Medical Hypothesis (Edinburgh) 9: 379 – 384.
21 Sharma, J.N. and Zeitlin, I.J. (1982). Reduced Plasma Kininogen Concentration by
Prostaglandin E2 in rats. European Journal of Pharmacology (Amsterdam) 83: 119 –
121.
20 Sharma, J.N. and Zeitlin, I.J. (1981). Altered Plasma Kininogen in Clinical Hypertension.
28
Curriculum Vitae of Jagdish N. Sharma
Lancet (Lond.) 1: 1259 – 1260.
19 Sharma, J.N., Zeitlin, I.J., Brooks, P.M., Buchanan, W.W. and Dick, W.C. (1980). The Action
of Aspirin on Plasma Kininogen and Other Proteins in Rheumatoid Patients. Clinical
and Experimental Pharmacology and Physiology (Oxford) 7: 347 – 354.
18 Sharma, J.N. and Buchanan, W.W (1980). Some Modern Aspects of the Mode of Action
of Non-steroidal Anti-inflammatory Drugs. Pharmatherapeutica (Lond.) 2: 387 – 396.
17 Sharma, J.N. and Buchanan, W.W. (1979). Kinin System in clinical and Experimental
Rheumatoid Inflammation: Short review. Current Medical Research and Opinion
(Lond.) 6: 314 – 321.
16 Sharma, J.N. (1978). The Effect of Prostaglandins (PGE2 and PGF2) on Plasma
Kininogens Levels in the Rat. Biomedicine (Paris) 29: 292 – 293.
15 Sharma, J.N. and Zeitlin, I.J. (1977). Indomethacin in Low Concentration Potentiates the
Action of Some Spasmogens on the isolated Oestrous Rat Uterus. Journal of
Pharmacy and Pharmacology (Lond.) 29: 316 – 317.
14 Sharma, J.N. (1977). Changes in Biochemical Parameters Associated with Experimental
Arthritis in Rabbits. Biomedicine (The European Journal of Clinical and Biological
Research) (Paris) 27: 252 – 255.
13 Sharma J.N. and Sharma, J.N (1977). Comparison of Anti-inflammatory Activity of
Commiphora Mukul (an indigenous drug) with Phenylbutazone and Ibuprofen in
Experimental Arthritis Induced by Mycobacterial Adjuvant. Arzeneimittel Forschung
(Drug Research) (Germany) 27: 1455 – 1457.
12 Sturrock, R.D., Sharma, J.N. and Buchanan, W.W. (1977). Evidence of Rheumatoid
Arthritis in Ancient India. Arthritis and Rheumatism (U.S.A) 20: 42 – 44.
11 Zeitlin, I.J., Sharma, J.N., Brooks, P.M. and Dick, W.C. (1977). An Effect of Indomethacin
on raised Plasma Kininogen Levels in Rheumatoid Patients, In “Chemistry and Biology
of the Kallikrein – Kinin System in Health and Disease”. Edited by Pisano, J.J. and
Austen, K.F. United States Government Printing Office, Washington, D.C., pp. 483 – 486.
29
Curriculum Vitae of Jagdish N. Sharma
10 Sharma, J.N., (1976). Studies on Plasma Kinin Precursors in Rheumatoid Arthritis.
Ph.D. Thesis. The University of Strathclyde, Glasgow, Scotland, U.K.
9 Zeitlin, I.J., Sharma, J.N., Brooks, P.M. and Dick W.C. (1976). Raised Plasma Kininogen
levels in Rheumatoid Arthritis: Response to Therapy with Non-Steroidal Anti-
inflammatory Drugs. Advances in Experimental Medicine and Biology (New York) 70:
335 – 343.
8 Sharma, J.N., Zeitlin, I.J., Brooks, P.M. and Dick, W.C. (1976). A Novel Relationship
Between Plasma Kininogen and Rheumatoid Diseases. Agents and Actions (Basel) 6:
148 – 153.
7 Sharma, J.N., Zeitlin, I.J., Brooks, P.M. and Dick, W.C., (1975). Raised Plasma Kininogen
Levels in Rheumatoid Arthritis: Response to Idomethacin and Relationship to clinical
Indices. Annals of Rheumatic Diseases (Lond) 34: 464.
6 Brooks, P.M., Dick, W.C., Sharma, J.N. and Zeitlin, I.J. (1974). Changes in Plasma
Kininogen Levels Associated with Rheumatoid Arthritis. British Journal of Clinical
Pharmacology 1: 351 P
5 Sharma, J.N. Sharma, J.N. and Arora, R.B. (1973). Abnormal Pattern of Serum Proteins
and Alkaline Phosphatase Activity in Rheumatoid Arthritis and Indication of Liver
Dysfunction. Rheumatism 8: 142 – 147.
4 Sharma, J.N., Sharma, J.N and Arora, R.B. (1973). Arthritis and Liver Function.
Rheumatism 8: 119 – 128.
3 Sharma, J.N. (1972). Liver Functions is arthritis and their Modification Drugs: An
Experimental and Clinical Study. M. Sc. (Pharmacology) Thesis. The All India Institute
of Medical Sciences, New Delhi, India.
2 Sharma, J.N., Sharma J.N., Shastri H.D. and Arora, R.B. (1972). Beneficial Effect of
Fraction A of Gum Guggal in Arthritis. A clinical appraisal. Rheumatism. 8: 21 – 53
1 Sharma, J.N., Sharma, J.N. and Arora, R.B. (1972). Beneficial Effect of fraction A of Gum
Guggal in Arthritis and Liver Functions in Clinical and Experimental Arthritis.
Rheumatism (New Delhi) 7: 20 – 21.
30
Curriculum Vitae of Jagdish N. Sharma
XVI. ABSTRACTS AND PRESENTATIONS IN INTERNATIONAL AND NATIONAL
CONFRENCES:
1. Zeitlin, I. J., Sharma, J. N., Brooks, P. M. and Dick, W. C. (1974). An Effect of Indomethacin
on Raised Plasma Kininogen Levels in Rheumatoid Patients. Paper presented in the
Conference on “Chemistry and Biology of the Kallikrien- Kinin System in Health and
Disease”. Organized by the Fogarty International Center for Advanced Study in the
Health Sciences and the National Institute of Health, Bethesda, Maryland, U. S. A.
October 20- 23.
2. Brooks, P. M., Sharma, J. N., Zeitlin, I. J. and Dick, W. C. (1975). Plasma Kininogen and
Rheumatoid Disease. Scandinavian Journal of Rheumatology 4 (Suppl. 8): Abstract No.
094.
3. Zeitlin, I. J., Sharma, J. N., Brooks, P. M., and Dick, W. C. (1976). Raised Plasma Kininogen-
Levels in Rheumatoid Patients- Response to Therapy with Nonsteroidal Anti-
Inflammatory Drugs. Agents and Actions 6: 449.
4. Zeitlin, I. J., Sharma, J. N., Brooks, P. M., Dick, W. C., Mackenzie, J. F., Russell, R. I., Strong,
A. M. and Thomson, J. (1977). Changes in Plasma Kininogen Levels Associated with
Inflammatory Diseases. Scottish Medical Journal 22: 191.
5. Zeitlin, I. J., Sharma, J. N., Brooks, P. M. and Dick, W. C. (1978). Studies on the Systematic
Kinin System in Rheumatoid Arthritis. International Congress of Inflammation, Bologna,
Italy, pp. 198.
6. Sharma, J. N. (1980). Does Prostaglandin E2 Cause Release of Plasma Kinins in the Rat?
Arachidonic Acid Cascade Symposium (European Society of Biochemical
Pharmacology), Seventh Congress of the Polish Pharmacological Society, pp. 205.
31
Curriculum Vitae of Jagdish N. Sharma
7. Sharma, J. N., Fernandez, P. G., Kim, B. K., Triggle, C. R., Idikio, H. and Laher, I. (1983).
Blood Pressure control and Hypertensive Heart Changes in the Dahl (D) Rat: MK- 421 (an
angiotensin converting Enzyme inhibitor) Versus Hydrochlorothiazide. Clinical research
31: 335A.
8. Sharma, J. N., Fernandez, P. G., Kim, B. K., and Triggle, C. R. (1983). Antihypertensive
Efficacy of MK- 241 (an angiotensin converting enzyme inhibitor, ACEI) and
Hydrochlorothiazide (HTZ) in Conscious Dahl Sensitive (S) and Resistant (R) Rats.
Clinical Research 31: 335A.
9. Fenandez, P. G., Sharma, J. N., Kim, B. K., Triggle, C. R., Idikio, H. and Laher, I. (1983). Left
Ventricular Regression and Blood Pressure Control on the Dahl (D) Rat with MK- 421 (an
angiotensin converting enzyme inhibitor, ACEI) and Hydrochlorothiazide (HTZ). Clinical
Research 31: 332A.
10. Fernandez, P. G., Kim, B. K., Sharma, J. N., Indikio, H. and Triggle, C. R. (1983). Left
Ventricular Regression (LVR) in association with Blood Pressure Control in the Dahl
Model of Hypertensive Rats (DS and DR) Treated with Enalpril Maleate (MK- 241) (an
angiotensin converting enzyme inhibitor) or Hydrochlorothiazide (HTZ). Clinical and
Investigative Medicine 6 (Suppl. 2): 55.
11. Alhaboubi, A. H., Bannett, D., Sharma, J. N., Thomas, G. R. and Zeitlin, I. J. (1984). A
Synovial Amidase Acting on Tissue Kallikrein- Selective Substrate in Clinical
Experimental Arthritis. Presented in the International Kinin Conference, Savannah, GA
30912, U. S. A.
12. Sharma, J. N., (1987). Contribution of Kinin System to the Anti- Hypertensive Action of
Angiotensin Converting Enzyme Inhibitors (ACEIs). Kinin 1987 Tokyo International
Congress, pp. 25 (a- 1- 08).
13. Sharma, J. N. (1987). The Kallikrein- Kinin System and Hypertension. Satellite
Symposiums of International Kinin Congress in Sapporo, Japan, pp. 33.
32
Curriculum Vitae of Jagdish N. Sharma
14. Sharma, J. N. (1989). The Kallikrein- Kinin System (KKS) in Joint Inflammatory Disease.
3rd Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunomodulators, Monte Carlo, pp. 26.
15. Sharma, J. N. (1989). The Kinin System in Hypertension and Inflammation Malaysian
Society of Pharmacology and Physiology, Penang, Malaysia. Abstract of Special Lecture
pp. S1- S2.
16. Sharma, J. N., Mohsin, S. S. J., Stewart, J. M., Vavrek, R. and Lockman, A. (1989). The Effect
of a New Synthetic Antagonist to Bradykinin (BK) on Acute Antihypertensive Action of
Captopril in Spontaneously Hypertensive Rats (SHR). Malaysian Society of
Pharmacology and Physiology, Penang, Malaysia. Abstract pp. C24.
17. A. Akbar, Sharma, J. N. and Mohsin, S. S. J. (1989). Influence of the Epithelium on
Responsiveness of Isolated Guinea- Pig Tracheal of Agents. Malaysian Society of
Pharmacology and Physiology, Penang, Malaysia. Abstract pp. C8.
18. Mohsin, S. S. J. and Sharma, J. N. (1989). Does the Kidney Release Hypotensive
Substance? Malaysian Society of Pharmacology and Physiology, Penang, Malaysia.
Abstract pp. C20.
19. Sharma, J. N. (1991). Participation of the Kallikrien- Kinin System in the Pathogenesis of
Inflammatory Joint Disease. 4th Intersciences World Conference on Inflammation,
Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 66.
20. Sharma, J. N. (1991). Involvement of Kinin- Forming System in the Physiopathology of
Rheumatoid Inflammation. International Kinin conference towards Understanding the
Molecular Basis of Kinin Action, Munich. Abstract pp. 167.
21. Sharma, J. N., Stewart, J. M., Mohsin, S. S. J., Katori, M. and Vavrek, R. (1991). Influence of
a Kinin Antogonist on Acute Hypotensive Responses Induced by Bradykinin and
Captopril in Spontaneously Hypertensive Rats. International Kinin Conference Towards
Understanding the Molecular Basis of Kinin Action, Munich. Abstract pp. 346.
33
Curriculum Vitae of Jagdish N. Sharma
22. Sharma, J. N. (1993). Tissue and Plasma Kallikreins Activities in the Regulation of
Adjuvant Arthritis in Rats. Intersciences World Conference on Inflammation,
Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 183.
23. Sharma, J. N. (1993). Inhibition of Adjuvant Inflammation in Rats by the Kinin Receptor
Antagonist Hoe 140. Intersciences World Conference on Inflammation, Antirheumatics,
Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 184.
24. Sharma, J. N., Srivastava, K. C. and Mustafa, T. (1993). Ginger (Zingibar officinale) in
Rheumatism and Musculoskeletal Disorders. 5th Intersciences World Conference on
Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland.
Abstract No. 123.
25. Sharma, J. N. (1993). The Role of Kallikrein- Kinin System in Hypertensive Disease. Guest
Lecture of the 11th Iranian Congress of Physiology and Pharmacology. Tabriz University
of Medical Sciences, Tabriz, Iran. Abstract No. L- 7.
26. Sharma, J. N. and Mohsin, S. S. J. (1993). Effect of a Bradykinin Antagonist on Adjuvant
Arthritis in Rats. 10th Scientific Meeting of the Malaysian Society of Pharmacology and
Physiology. Kelantan. Abstract No. A6. Asian Pacific Journal of Pharmacology 8 (Suppl.
2): S23.
27. Sharma, J. N. and Srivastave, K. C. (1993). Anti- inflammatory Properties of Eugenol and
Ginger Oil in Rats Arthritis Induces by Mycobacterial Adjuvant. The International
Conference on the Use of Traditional Medicine and Other Natural Products in Health-
Care, Penang, Malaysia. Abstract No. OA- 2.
28. Sharma, J. N. (1993). Alterations in Kallikreins Levels in Experimental Arthritis in Rats.
International Kinin Conference, Guaruja, Brazil. Abstract No. 9. 07.
29. Sharma, J. N. (1993). Altered Blood Pressure Responses to Converting Enzyme Inhibition
with Aprotinin- Induced Kallikrein- Kinin System Blockade in Spontaneously
Hypertensive Rats. International Kinin Conference, Guaruja, Brazil. Abstract No. 8. 12.
34
Curriculum Vitae of Jagdish N. Sharma
30. Sharma, J. N. (1993). Anti- inflammatory Activity of a Bardykinin Antagonist (Hoe 140) in
Rats Experimental Arthritis. International Kinin Conference, Guaruja, Brazil. Abstract No.
9. 06.
31. Sharma, J. N. (1994). Changes in Kallikreins Levels Associated with Adjuvant Arthritis in
Rats. Satellite Symposia of the XIIth International Union of Pharmacology Congress,
Montreal, Canada. Canadian Journal of Physiology & Pharmacology 72 (Suppl. 2): P1. 15,
pp. 39.
32. Sharma, J. N. (1994). Suppression of Hypotensive Responses of Captopril and Enalapril
by Kallikrien Inhibitor in Hypertensive Rats. Satellite Symposia of the XIIth International
Union of Pharmacology Congress, Montreal, Canada. Canadian Journal of Physiology &
Pharmacology 72 (Suppl. 2): P1. 14, pp. 39.
33. Sharma, J. N. (1995). Prospect of Kinin Receptor Antagonist as Novel Antirheumatic
Drug. 6th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunomodulators, Geneva, Switzerland. Abstract No. 35.
34. Uma, K., Sharma, J. N. and Noor, A. R. (1995). Importance of Kinin System in Preventing
Left Ventricular Hypertrophy in Diabetic and Hypertensive Rats. 6th Intersciences World
Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva,
Switzerland. Abstract No. 33.
35. Kadir, Z., Sharma, J. N., Uma, K. and Sulaiman, S. A. (1995). Changes in Kallikrein- Kinin
System in Experimental Epilepsy in Rats. 6th Intersciences World Conference on
Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland.
Abstract No. 34.
36. Sharma, J. N. and Uma, K. (1995). Effect of Captopril on Kallikrein- Kinin System in
Hypertensive and Normotensive Rats with and without Diabetes. 14th International
Symposium on Kinins, Denver, September 1995. Abstract No. C51.
35
Curriculum Vitae of Jagdish N. Sharma
37. Uma, K. and Sharma, J. N. (1995). Changes in Cardiac and Renal Kallikrein- Kinin System
in Hypertensive and Normotensive Rats with and without Diabetes. 14th International
Symposium on Kinins, Denver, September 1995. Abstract No. C47.
38. Akbar, A., Sharma, J. N. and Gan, E. K. (1995). Effect of Indomethacin on Bradykinin-
Induced Responses in the Guinea- Pig Tracheal Smooth Muscle. 14th International
Symposium on Kinins, Denver, September 1995. Abstract No. C33.
39. Sharma, J. N., Yusof, A. P. M. and Ishak, F. I. (1996). Significance of the Kinin System in
Pathophysiology of Inflammatory Joint Disease. 16th
Asian Congress of Pharmaceutical
Sciences, Kuala Lumpur, Malaysia, November 1996. Abstract No. A- 14.
40. Sharma, J. N., Yusof, A. P. M. and Ishak, F. I. and Srivastava, K. C. (1997). Suppressive
Effects of Eugenol and Ginger Oil on Arthritic Rats: Possible Role of Kallkrein. 7th
Intersciences World Conference on Inflammation, Antirheumatics, Analgesics,
Immunodulators, Geneva, Switzerland, May 1997. International Journal of Tissue
Reactions 19: 54.
41. Sharma, J. N., Uma, K. and Yusof, A. P. M. (1998). Altered Tissue and Plasma Kininogen
Levels in Hypertensive and Diabetic Rats. 15th
International Conference on Kinins, Nara,
Japan, October 1998. Abstract No. O- V- 3 (pp. 71).
42. Abbas, S. A., Sharma, J. N. and Yusof, A. P. M. (1998). The Effect of Bradykinin and Its
Antagonist on Survival Time After Coronary Artery Occlusion in Hypertensive and
Normotensive Rats. 15th
International Conference on Kinins, Nara, Japan, October 1998.
Abstract No. P- 14 (pp. 83).
43. Samud, A. M., Asmawi, M. Z. and Sharma, J. N. (1998). Anti- inflammatory Activity of
Crinum Asiaticum Plant and Its Effect on Bradykinin Induced Contractions on Isolated
Uterus. 15th International Conference on Kinins, Nara, Japan, October 1998. Abstract No.
P- X- 18 (pp. 145).
44. Abbas, S. A., Sharma, J. N., Yusof, A. P. M. and Shah, R. P. (1999). The Effect of Tissue
Kallikrein and Captopril on Survival Time After Coronary Artery Ligation in
36
Curriculum Vitae of Jagdish N. Sharma
Spontaneously Hypertensive Rats. 14th Meeting of the Malaysian Society of
Pharmacology and Physiology, Penang, Malaysia, May 1999. Abstract No. OR6.
45. Asmawi, M. Z., Samud, A. M., Sharma, J. N., Yusof, A. P. M. (1999). Anti- inflammatory
Activity of the Fractional Extract of Plant Crinum Asiaticum, 14th Meeting of the
Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, May 1999.
Abstract No. OR 11.
46. Abbas, A. S., Sharma, J. N., Yusof, A. P. M., Das P. K. and Shah, R. P. (1999). The Effect of
Bradykinin on Cardiac Morphology on Normotensive and Hypertensive Rats. 14th
Meeting of the Malaysian Pharmacology and Physiology, Penang, Malaysia, May 1999.
Abstract No. P1.
47. Sharma, J. N. (2000). Kinin System in Protecting the Heart. National Symposium on
Health Sciences, Kuala Lumpur, Malaysia, April 2000. Abstract No 80.
48. Sharma, J. N., Abbas, S. A., Yusof, A. P. M. and Shah, R. P. (2002). Evaluation of tissue
kallikrein and captopril activities on survival time after coronary artery ligation in
hypertensive rats. Kinin 2002: The 16th
International Conference, Charleston, SC, USA,
May 26- 31, 2002. Abstract No. O-68.
49. Sharma, J. N. (2003). Recent advances in the kallikrein-kinin system in inflammatory
disorders. International Conference on Inflammopharmacology 2003, Royal College of
Physicians of Edinburgh, UK, April 22-24, 2003. Inflammopharmacology Abstract No. 36
(pp.56-57).
50. Sharma, J. N. (2003). Significance of the kinin system in the cardiovascular disorders.
7th
International symposium on Pharmaceutical Sciences, Ankara University Faculty of
Pharmacy, Ankara, Turkey, June 24-27, 2003. Proceeding Abstract No. PL-29 (pp.96-98).
51. Sharma, J. N. (2004). The kallikrein-kinin system in cardiovascular disorders- a new
therapeutic modality found? The Philippines Society of Experimental and Clinical
Pharmacology Meeting, Manila, Philippines, May 7, 2004.
37
Curriculum Vitae of Jagdish N. Sharma
52. Sharma, J. N. (2004). Bradykinin agonists in the treatment of cardiovascular disorders. The
20th
Federation of Asian Pharmaceutical Association Congress, Bangkok, Thailand,
November 30 –December 3, 2004. Proceeding Abstract pp. 207.
53. Sharma, J. N. (2005). The role of nutraceuticals in therapeutics: myth or reality.
The 20th
Scientific Meeting of the Malaysian Society of Pharmacology and Physiology,
Penang, Malaysia, April 25-27, 2005, Proceeding Abstract pp 1.
54. Sharma, J. N., Kadir, Z and Uma, K . (2007). Evaluation of the kinin-forming components in
experimental epilepsy in rats. KININ 2007, 2nd
International Conference on Exporing the
Future of Vascular and Inflammatory mediators, Berlin, Germany, May 30-June 2, 2007.
Proceeding Abstract P61, pp.119.
55. Sharma, J. N. and Abbas, S. A. (2008). Effect of bradykinin antagonist on beneficial effect of
captopril on duration of survival after acute coronary artery ligation in hypertensive rats.
The IXth World conference on Clinical Pharmacology and Therapeutics, Quebec, Canada,
July 27-August 1, 2008. Proceeding abstract No. T2TH041.
56. Sharma, J. N. and Uma, K. (2009). Effect of captopril on cardiac wall thickness, blood
pressure and kinin-components in diabetic Wistar-Kyoto (WKY) rats. The 2nd
Kuwait
International Pharmaceutical Conference (KIPC), Kuwait, March 1 to March 3, 2009.
Proceeding abstract No. 35. Poster.
57. Sharma, J. N. (2009). Role of bradykinin system in hypertension: prospects for future drug
therapy. 4th
Asian Association of Schools of Pharmacy and 9th
Malaysian Pharmaceutical
Society Conference, Penang, Malaysia. June 10 to June 13, 2009. Abstract No. page
58. Sharma, J. N. (2010) : Bradykinin system and rheumatoid arthritis: An overview.
24th
Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Shah
Alam, Kuala Lumpur, Malaysia, June 2-3, 2010. Abstract Page No. 35.
38
Curriculum Vitae of Jagdish N. Sharma
59. Sharma, J. N. (2011). Effect of indomethacin and prednisolone on tissue kallikrein activity in
arthritic rats. The 3rd
Kuwait International Pharmaceutical Conference (KIPC 2011), Kuwait,
14-16 February 2011. Proceeding abstract No. 63, page 97. Poster.
60. Sharma, J. N. (2011). Kallikrein-kinin pathway in cardiovascular and renal system:
possibility for new drug development. 25th
Scientific Meeting of the Malaysian Society of
Pharmacology and Physiology, Serdang, Selangore, Malaysia, May 25- 26, 2011. Abstract
Page No. 14. Plenary Lecture 4.
61. Sharma, J. N. (2012). Bradykinin system: Role in hypertension and diabetes. 26th
Scientific
Meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, May
18-20, 2012. Abstract Page No. 39. Plenary Lecture 6.
62. Sharma, J. N. (2013). : Kallikrein-kinin pathways in cardio-renal system: prospect of new
drug development. 27th
Scientific Meeting of the Malaysian Society of Pharmacology and
Physiology, Kuantan, Malaysia, September 6 - 8, 2013. Abstract Page 39-40. Plenary Lecture
3.
63. Sharma, J. N.; Al-Shoumer, K. A. S., Matar, K. M. and Madathil, N. V. (2013). Abnormal
regulation of bradykinin-foring components in Kuwaiti patients with type 2 diabetes. The 5th
International Conference on Fixed Combination in the Treatment of Hypertension, Dyslipidemia
and Diabetes Mellitus, Bangkok, Thailand, November 21-24, 2013. Oral presentation.
64. Sharma, J. N.; Al-Shoumer, K. A. S., Matar, K. M. and Madathil, N. V. (2014).
Abnormal pattern of bradykinin forming components and nitric oxide in Kuwaiti
patients with type 2 diabetes, 19th
HSC Poster Conference, Kuwait University,
Kuwait. May 21-24, 2014. Poster presentation no. 184.
39
Curriculum Vitae of Jagdish N. Sharma
65. Sharma, J. N. , Al-Shoumer, K. A. S., Matar, Madathil, N. V. and Al-Moalem,
A.M.K. ( 2015). 'Influence of oral hypoglycemic agent on kininase II and nitric
oxide activities in Kuwaiti patients with type 2 diabetes,' 20th
HSC Poster
Conference, Kuwait University, Kuwait. May 5-7 , 2014. Poster presentation no.
180.
ADVISOR AND EVALUATOR OF NATINAL AND INTERNATIONAL RESEARCH
GRANTS
INTERNATIONAL:
40
Curriculum Vitae of Jagdish N. Sharma
1. Telethon Combatti La Distrofia mauculare E Le Altre Malattie Genetiche, Rome, Italy.
July 1999.
2. International Foundation for Science, Stockholm, Sweden. October 2001.
3. Raine Priming Grants, School of Medicine and Pharmacology, The University of Western
Australia, Perth, WA. May 2010.
NATIONAL:
1. Kuwait Foundation for the Advancement of Science, Kuwait. April, 2003.
2. Member of the Kuwait University Scientific Consultant Council, June, 2003.
3. Kuwait University Research Project, Kuwait, April, 2004.
4. Kuwait University Research Project, Kuwait, May, 2006.
5. Kuwait University Research Project, Kuwait, February, 2008.
41
Curriculum Vitae of Jagdish N. Sharma
42

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CV of JN SHARMA

  • 1. Curriculum Vitae of Jagdish N. Sharma CURRICULUM VITAE 1 JAGDISH N. SHARMA Ph.D. (UK), D.Sc. (UK), F.C.P. (USA), F. I. Biol., FSB (UK), Professor Department of Pharmacology and Therapeutics, Faculty of Pharmacy Health Sciences Center Kuwait University P.O.Box 24923, Safat 13110, Kuwait
  • 2. Curriculum Vitae of Jagdish N. Sharma CONTENTS PAGE NO I. PERSONAL PARTICULARS AND PRESENT APPOINTMENT 3 II. ACADEMIC QUALIFICATIONS AND FELLOWSHIPS 3 III. PRESENT AND PREVIOUS ACADEMIC AND RESEARCH POSITIONS 4 IV. ADMINISTRATIVE DUTIES AS A CHAIRMAN 6 V. EDITORIAL AND ADVISORY BOARD MEMBER OF INTERNATIONAL 6 JOURNALS VI. ADVISORY BOARD MEMBER OF INTERNATIONAL CONFERENCES 7 VII. EDITORIAL BOARD MEMBER OF NATIONAL JOURNALS 7 VIII. AWARDS AND EXTERNAL ASSESSOR FOR PROMOTION TO FULL PROFESSOR 8 AND TO THE RANK OF ASSOCIATE PROFESSOR 9 IX. MEMBERSHIP OF PROFESSIONAL LEARNED SOCIETY 9 X. POSITIONS IN INTERNATIONAL CONFERENCES 9 XI. SPECIAL INVITED GUEST LECTURES AND PLENARY LECTURE 9 XII. RESEARCH DEVELOPMENT AREAS AND RESEARCH GRANTS Supervision of Research projects for Higher Degrees 11 Short –term University research grants 11 Long-term Research and development Grants 12 Personal Research Development 12 International Research Collaboration 12 XIII. EXAMINER OF PH.D. THESES 13 XIV. TEACHING 14 Undergraduate (M.D., M.B. Ch.B., B. Pharm. (Hons) Nursing and Medical Technologist Postgraduate (M.Med., M. Pharm., M.Sc., Ph.D.) XV. BOOK AND FULL PUBLICATIONS 16 XVI. ABSTRACTS AND PRESENTATIONS IN INTERNATIONAL AND 27 NATIONAL CONFERENCES XVII. ADVISOR AND EVALUATOR OF INTERNATIONAL RESEARCH GRANTS 34 XVIII. REFERENCES 36 2
  • 3. Curriculum Vitae of Jagdish N. Sharma I. PERSONAL PARTICULARS Surname SHARMA First & Middle Names JAGDISH NARAIN Nationality Canadian Date of Birth 15 July, 1947 Marital Status Married and having 4 children Permanent Address 79 Stirling Crescent St. John’s NL, A1A 4J9, Canada T el: +1-709-754-2464 Institutional Corresponding Professor J.N. Sharma Address Department of Pharmacology and Therapeutics Faculty of Pharmacy, Health Sciences Center Kuwait University P.O.Box 24923, Safat 13110, Kuwait Email: j.n.sharma@hsc.edu.kw II. ACADEMIC QUALIFICATIONS AND FELLOWSHIPS Degree Year University and Institution Specialization B.V.Sc. & A.H. 1970 Jawaharlal Nehru Agricultural Veterinary Medicine (D.V.M.) University, Jabalpur, M.P. India and Surgery M.Sc. 1973 All-India Institute of Medical Medical Sciences, New Delhi, India Pharmacology Ph.D. 1976 University of Strathclyde, Pharmacology Glasgow, Scotland, UK D.Sc. 2011 Calamus International University, Health Sciences 3
  • 4. Curriculum Vitae of Jagdish N. Sharma London , UK. F.C.P. 1995 Fellow of the American College of Clinical Pharmacology, New York, USA F.I.Biol. 1997 Fellow of the Institute of Biology, London, UK C. Biol., F.S.B. 2009 Fellow of the Society of Biology, London UK III. PRESENT AND PREVIOUS ACADEMIC AND RESEARCH POSITIONS Full Professor Department of Applied Therapeutics Faculty of Pharmacy, Kuwait University, Kuwait October 1999 – to date Founding Chairman Department of Pharmacology and Applied Therapeutics Faculty of Pharmacy, Kuwait University, Kuwait January 2000 – May 2005. Full Professor Department of Pharmacology School of Medical Sciences and Pharmaceutical Sciences Universiti Sains Malaysia Penang, Malaysia July 1991 – October 1999 Associate Professor Department of Pharmacology School of Medical Sciences Universiti Sains Malaysia Penang, Malaysia January 1987 – June 1991 Guest Professor Faculty of Pharmacy, Chiang Mai University Chiang Mai, Thailand, June, 2006. 4
  • 5. Curriculum Vitae of Jagdish N. Sharma Visiting Professor Department of Surgery, Faculty of Medicine Queen’s University Kingston, Ontario, Canada December 1991 Guest Speaker Faculty of Medicine Memorial University St. John’s, Newfoundland, Canada December 1991. Senior Research Fellow/ Faculty of Medicine and Nursing Visiting Professor Memorial University of Newfoundland St. John’s, Newfoundland, Canada. November 1981 – June 1983 – November 1986 Visiting Professor Department of Pharmacology Faculty of Medicine, University of Al-Fateh Tripoli, Libya March 1981 Consultant / Senior Division of Pharmacology and Toxicology Lecturer Medical School, University of Malta, Malta September 1980 – August 1981 Lecturer Department of Pharmacology Faculty of Medicine, University of Al-Fateh Tripoli, Libya March 1978 – August 1980 Visiting Research Fellow Department of Pharmacology and Physiology University of Strathclyde Glasgow, Scotland, U.K. September 1978 Postdoctoral Fellow Department of Pharmacology and Physiology 5
  • 6. Curriculum Vitae of Jagdish N. Sharma University of Strathclyde, Glasgow, U.K. October 1976 – March 1978 Demonstrator Department of pharmacology and Physiology University of Strathclyde Glasgow, Scotland, U.K. October 1975 – September 1976 Research Assistant / Department of Pharmacology Teaching Fellow All- India Institute of Medical Sciences New Delhi, India January 1971 – September 1973 IV. ADMINISTRATIVE DUTIES AS A CHAIRMAN 1. Development of the curriculum for Applied Therapeutics and Elective courses. 2. Chairman of the Department of Applied Therapeutics of academic and technical staff appointment committee. 3. Member of the Faculty of Pharmacy Council. 4. Member of the Dean’s Executive Committee for contributions to develop the faculty. 5. Member of the Faculty of Pharmacy selection committee for various departments. 6. Member of the Faculty of Pharmacy examination Board to monitor of the results of all the departments. 7. Chairman of the department of Applied Therapeutics scholarship committee to select local graduates to be trained for PhD in USA, UK or Canada. 8. Member of the Faculty of the Pharmacy promotion and renewal of contract committee for all the departments. 9. Review and Evaluation of the Performance of Department Chairmen of the Pharmacy and Medical Faculties. 10. Chairman of the Promotion-Revision Committee for Full Professor, Pharmacy Practice. 11.Chairman of the Selection Committee for the Chairman of Pharmaceutical Chemistry. 6
  • 7. Curriculum Vitae of Jagdish N. Sharma 12. Member of the distinguished teaching and research awards of the staff of the Faculty of Pharmacy. V-A. Honorary Advisor and Editor: 1. International Journal of Pharmacology and Pharmaceutical technology (India) from 2012 to date V-B. REGIONAL EDITOR FOR MIDDLE-EAST 1. Inflammopharmacology (UK) from 2006 to date. V- C. EDITORIAL AND ADVISORY BOARD MEMBER OF INTERNATIONAL JOURNALS 1. Agents and Actions (Inflammation Research) (Switzerland): Editorial Board Member from 1989 to 1992. 2. Experimental and Toxicologic Pathology (Formerly Experimental Pathology) (Germany): Advisory Board member from 1989 to 1996. 3. International Journal of Tissue Reactions (Switzerland): Editorial Board member from 1994 to 2005. 4. Asia Pacific Journal of Pharmacology (Singapore): Editorial Advisory Board Member from 1995 to 2006. 5. Current Drugs Ltd. (U.K): Evaluator for the Investigational Drugs Database from 1994 to 1998. 6. Journal of Pharmacology and Toxicology, Technical Editor (Academic Journals net, USA) from 2007 to 2009 7. Pharmacy Times (USA): Middle East Editorial Board Member from 2007 to date. 8. Inflammopharmacology (UK): Editorial Advisory Board Member from 1997 to date. 9. International Journal of Immunopathology and Pharmacology (Italy) from 2006 to 2014. 10. European Journal of Inflammation (Italy) from 2006 to date. 11. Archives of Medical Research (Mexico City) from 2006 to date. 12. Clinical Medicine: Endocrinology and Diabetes (New Zealand) from 2008 to date. 13. Clinical Medicine: Therapeutics (New Zealand) from 2009 to date. 7
  • 8. Curriculum Vitae of Jagdish N. Sharma 14. American Journal of Biomedical Sciences (USA) from 2009 to date. 15. Journal of Pharmaceutical Technology and Drug Research (UK) from 2011 to date. 16. Reviewer of Manuscripts for International Journals. VI. ADVISORY BOARD MEMBER OF INTERNATIONAL CONFERENCES 1. International Kinin Conference: International Advisory Board member. Guaruja, Brazil, 1993. 2. 5th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators: International Advisory Board Member. Geneva, Switzerland, 1993. 3. 6th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators: International Advisory Board Member. Geneva, Switzerland, 1995. 4. 14th International Symposium of Kinin: International Advisory Board Member. Denver, U.S.A., 1995. 5. 7th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators: International Advisory Board Member. Geneva, Switzerland, 1997. 6. The 15th International Conference on Kinin; International Advisory Board Member; Nara, Japan, 1998. 7. 8th Annual Health Sciences Poster Day, Faculty of Medicine, Kuwait University, Kuwait, 2003. VII. EDITORIAL BOARD MEMBER OF NATIONAL JOURNALS 1. Diagnosa (The Medical Bulletin of the School of Medical Sciences, Universiti Sains Malaysia) Editorial Committee Member from 1992 to 1993. 2. Malaysian Journal of Medical Sciences: Editorial Board Member from 1993 to 1995. VIII. REASEARCH GRANTS, AWARDS AND EXTERNAL ASSESSOR FOR PROMOTION TO FULL PROFESSOR 1. Research grant: Kuwait University 8
  • 9. Curriculum Vitae of Jagdish N. Sharma Principal Investigator: Clinical Priority research Grant No. PR 01/09; (Kuwait University) entitled “ Investigational study on bradykinin system and nitric oxide in healthy subjects, hypertensive and type -2 diabetic patients in Kuwait”. Total amount KD 41,595.00x US$3.60 for 4 years (2011 to 2015) Co-investigators: 1. Dr. Kamal A. S. Al-Shoumer, Associate Professor, Department of Medicine, FoM. 2. Dr. Kamal Matar, Associate Professor, Department of Pharmacology and Therapeutics, FoP. 3. The British Council Overseas Student Fee’s Award. October 1974 to September 1976 4. Research Fellowship awarded by the Merck, Sharp and Dohme (U.K). October 1974 to September 1976. 5. Post-doctoral Research Fellowship awarded by the Merck, Sharp and Dohme (U.K). October 1976 to September 1978. 6. Fellowship award from the 1st world Conference on Clinical Pharmacology (London). June 1980. 7. Three Short –term Research Grants from Universiti Sains Malaysia, Penang, Malaysia. September 1989 to August 1991 and April 1993 to March 1998 with the funding of M$ 100000.00 8. Research And Development Grant (IRPA) Award from The Ministry of Science, technology and Environment of Malaysia. From January 1993 with the funding of M$ 400000.00. 9. A. External Assessor for Promotion to the rank of Full Professor: Dr. Abdul Rahman H. Mohd. Noor, MBBCh, DCH, MSc, FRCP, Vice Dean , School of Medical Sciences, University Science Malaysia, Kubang Kerian, Kelantan, Malaysia. February 14, 2009. B. External Assessor for Promotion to the rank of Associate Professor: Dr. Sania Abdalla Ibrahim Shadad, PhD, Assistant Professor of Pharmacology, Faculty of Pharmacy, University of Khartoum, Khartoum, Sudan. March 17, 2009. C. External Assessor for Promotion to the rank of Associate Professor: Dr. Abdullah M. Al- Mohizea, PhD, Assistant Professor, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. February 14, 2010. 9
  • 10. Curriculum Vitae of Jagdish N. Sharma D. External Assessor for Promotion to the rank of Associate Professor: Dr. Fahad Ibrahim Abdul Rahman Al-Jenoohi, PhD, Assistant Professor, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. 31 May, 2010. E. External Assessor for Promotion to the rank of Full Professor: Dr. Fars Kaed Alanazi, Associate Professor, PhD, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. 27 September, 2011. F. External Assessor for Promotion to the rank of Associate Professor: Dr Mohamed Abbas Ibrahim Hamoud, PhD, Assistant Professor, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. 7 June, 2012. G. E. External Assessor for Promotion to the rank of Full Professor: Dr. Fahad Ibrahim Al- Jenoobi, PhD, Associate Professor, College of Pharmacy, King Saudi University, Riyadh, Saudi Arabia. April, 19, 2015. IX. MEMBERSHIP OF PROFESSIONAL LEARNED SOCIETY Member of the British Pharmacological Society of Great Britain. Member of Canadian Society of Physiology and pharmacology. Member of Canadian Society of Clinical Investigation (Canada). Member of Malaysian Society of Pharmacology and Physiology X. POSITIONS IN INTERNATIONAL CONFERENCES (ORAL SESSIONS) • Chairman 26th Scientific Meeting of the Malaysia Society of Pharmacology and Physiology. Poster Session. May 19, 2012. • Chairman 25th Scientific Meeting of the Malaysia Society of Pharmacology and Physiology. Symposia on Tissue Engineering. May 26, 2011. • Chairman 15th International Conference on Kinins. October 19 – 24, 1998. Nara, Japan. 10
  • 11. Curriculum Vitae of Jagdish N. Sharma • Chairman 7th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators. May 19 – 21, 1997. Geneva, Switzerland. • Chairman 6th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, March 28 – 30, 1995. Geneva, Switzerland. • Chairman Kinin International Congress. October 17 – 22, 1993. Guaruja, Brazil. • Chairman 5th Intersciences World Conference on Inflammation, Antirheumatics, Analgesic, Immunomodulators. April 25 – 28, 1993. Geneva, Switzerland. • Chairman The International Conference on the Use of Traditional Medicine and Other Natural Products in Health-Care. June 8 – 11, 1993. Geneva, Switzerland. • Chairman Kinin International Conference Towards Understanding the Molecular Basis of Kinin Actions. September 8 – 14, 1991. Munich, Germany. • Chairman 4th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators. April 15 – 18, 1991. Geneva, Switzerland. • Chairman 3rd Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators. March 15 – 18, 1989. Monte Carlo • Chairman Kinin International Conference, November 29 – December 3, 11
  • 12. Curriculum Vitae of Jagdish N. Sharma 1987. Tokyo, Japan XI. SPECIAL INVITED GUEST LECTURES AND PLENARY LECTURE 1. Department of Pharmacology, All- India Institute of Medical Sciences, New Delhi, India, July 1980. Lecture: “The Kallikrein –Kinin System”. 2. Symposium on Renal function, Hypertension and Kallikrein-Kinin System: Satellite Symposium of International Kinin Conference, Sapporo, Japan, December 1987. Lecture: “the Kallikrein- Kinin System and Hypertension”. 3. Department of Pharmacology, All –India Institute of medical Sciences, New Delhi, India, May 1989. Lecture: “Involvement of Kinin in the Action of Angiotensin Converting Enzyme Inhibitors”. 4. 8th Scientific meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, July 1989. Lecture: “ The Kinin System in Hypertension and Inflammation” 5. International Kinin Conference, Munich, Germany. September 1991. Lecture: “Involvement of the Kinin –Forming System in the Genesis of Joint Inflammatory Disease”. 6. Department of Surgery, Queen’s University Medical School, Kingston, Ontario, Canada, December1991. Lecture: “The Role of Kallikrein - Kinin System in the Genesis of Joint Inflammatory Disease” 7. Division of Basic Medical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Canada, December 1991. Lecture: “The Kallikrein – Kinin System in Blood Pressure Regulation”. 8. School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia, May 1992. 12
  • 13. Curriculum Vitae of Jagdish N. Sharma Professorial Public Lecture: “Significance of Bradykinin in Health and Disease”. 9. 11th Iranian Congress of Physiology and Pharmacology, Tabriz University of Medical Sciences, Tabriz, Iran, May 1993. Lecture: “The Role of Kallikrein- Kinin System in Hypertensive Disease”. 10. 7th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland, May 1997. Lecture: “Cardioprotective Effects of Kinin System and its Role in Inflammation” 11. Postgraduate Seminar in Cardiovascular Therapeutics, Universiti Sains Malaysia, Penang, Malaysia, November 1997. Lecture: “Significance of Kallikrein- Kinin System in Hypertension”. 12. International Conference of Stress, Prophylaxis and Treatment, Calcutta, India, January 1998. Lecture: “Kallikrein – KininSystem in Hypertension and Diabetes”. 13. Asthma in the 1990s: Current Insights and Future Outlook, Penang, Malaysia, October 1998. Lecture: “Inflammatory Mediators in Asthma” 14. Rheumatology update symposium, Faculty of Medicine, Kuwait University, Kuwait, January 2001. Lecture: “Drugs used in Patients with Common Rheumatic Diseases”. 15. International Conference on Inflammopharmcology 2003, Royal College of Physicians of Edinburgh, Scotland. April 2003. Lecture: “Recent advances in the kallikrein-kinin system in inflammatory disorders”. 16. 7th International Symposium on Pharmaceutical Sciences, Ankara University Faculty of Pharmacy, Ankara, Turkey, June 2003. Lecture: “Significance of the kinin system in the cardiovascular disorders. 17. The Philippines Society of Experimental and Clinical Pharmacology Meeting, Faculty of 13
  • 14. Curriculum Vitae of Jagdish N. Sharma Medicine and Surgery, Department of Pharmacology, University of Santo Tomas, Manila, Philippines, May 2004. Lecture: “The kallikrein-kinin system in cardiovascular disorders- a new therapeutics modality found? 18. 20th Federation of the Asian Pharmaceutical Association Congress, Bangkok, Thailand, November 30 – December 3, 2004. Lecture: “Bradykinin agonists in the treatment of cardiovascular disorders”. 19. 20th Scientific meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, April 25-29, 2005. Plenary lecture: “The role of nutraceuticals in therapeutics: myth or reality. 20. Faculty of Pharmacy, Chiang Mai University, Thailand, June 11-14, 2006. Guest lectures: Important roles of the kinin-forming components in cardiovascular and inflammatory conditions, and the role of nutraceuticals in therapeutics: myth or reality. 21. 4th Asian Association of Schools of Pharmacy and 9th Malaysian Pharmaceutical Society Pharmacy Scientific Conference 2009 , Penang, Malaysia, June 10-13, 2009. Invited Lecture: “Role of the bradykinin system in hypertension: Prospects for future drug Therapy. 22. 24th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Shah Alam, Kuala Lumpur, Malaysia, June 2-3, 2010. Special Lecture: Bradykinin system and rheumatoid arthritis: An overview. 23. 25th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Serdang, Selangore, Malaysia, May 25 - 26, 2011. Plenary Lecture: Kallikrein-kinin pathway in cardiovascular and renal systems: possibility for new drug development. 24. 26th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, May 18 - 20, 2012. Plenary Lecture: Bradykinin system: Role in hypertension and diabete. 14
  • 15. Curriculum Vitae of Jagdish N. Sharma 25. 27th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Kuantan, Malaysia, September 6 - 8, 2013. Plenary Lecture: Kallikrein-kinin pathways in cardio-renal system: prospect of new drug development. XII. RESEARCH AND DEVELOPMENT AREAS Supervision of Research Projects for Higher Degrees 1. Ph.D. (Doctor of Medical Science) under the Japanese Society for Promotion of Science. Research work on the “The role of Kallikrein – Kinin System in Experimental Hypertension”. Candidate’s name: S.S.J. Mohsin, B.Sc,. M.Sc. (Australia), Associate Professor and Ex-Head of Pharmacology, School of Medical Sciences, Universiti of Sains Malaysia. The degree was awarded in March 1992 from the Kitasato University School of Medicine, Kanagawa, Japan. 2. M.Sc. By Research work on “Pharmacological Studies of Some Mediators on Guinea –Pig Tracheal Smooth Muscle”. Candidate’s Name: Dr. Akbar Ali, M.B.B.S. (Rangoon). Completed in 1994. 3. M.Sc. By Research work on “The studies on Kallikrein –Kinin System in Normotensive and Hypertensive Rats with and without Diabetes”. Candidate’s Name: Dr. K. Uma, M.B.B.S. (Madras). Completed in 1995. 4. M.Sc. By Research work on “Role of the Kallikrein System in Cardiac Arrhythmias induced by Coronary Artery Ligation in Rats”. Candidate’s name: S. Atif Abbas, B.Pharm. (Pakistan). Completed in 1999. 5. M.Sc. By Research work on “Anti-Inflammatory Activity of the Fractinated Extract of Plant Crinum Asiaticum (Family: Amaryllidacene)”. 15
  • 16. Curriculum Vitae of Jagdish N. Sharma Candidate’s name: A. Mabruk Samud, B.Pharm. (Libya). Completed in 1998. Short – Term University Research Grants (1989 – 1991 and 1993 – 1994 – 1998) 1. Role of Kinin System in experimental arthritis 2. Role of Kinin System in experimental hypertension. 3. Involvement of Kallikrein – Kinin System in experimental epilepsy. Long – Term Research Development Grant from the Ministry of Science, Technology and Environment Malaysia 1. Investigations on the role of humoral factors with the emphasis on the Kallikrein – Kinin System experimental models (1993 – 1995). a. Hypertension b. Inflammatory Joint disease c. Asthma 2. Studies on cardiac and renal Kallikrein –Kinin System in Hypertension (1997 – 1999). Personal Research and Development 1. Critical evaluations of the molecular actions of Kallikreins–Kininogens-Kinins–Kininases System and its interactions with arachidonic acid products, platelet activating factor, cytokines and products released by endothelial cells in experimental hypertension, inflammation, asthma and diabetes. 2. Contributions of the Kallikreins-Kininogens-Kinins-Kininases and related agents in the pathophysiology of inflammation and cardiovascular-renal disorders with special reference to hypertension and diabetes. 3. Evaluations of the mode of actions of antihypertensive agents dependant upon the Kallikrein – Kinin System. 4. Mechanism of actions and toxicity of anti-inflammatory agents with reference of cardiovascular, gastrointestinal, renal and airway systems. 5. Blood pressure regulation by the Kallikrein-Kinin System, and its role in the pathophysiology of left ventricular hypertrophy in the presence of hypertension. 6. Endogenous agents in regulation of tracheal smooth muscle in experimental and clinical asthma. 16
  • 17. Curriculum Vitae of Jagdish N. Sharma 7. Kallikrein – Kinin System in experimental and clinical diabetes. International Research Collaboration 1. Professor M. Katori, Department of Pharmacology, Kitasato University, School of Medicine, Kitasato, Kanagawa, Japan. 2. Professor J.M. Stewart, Department of Biochemistry, School of Medicine, University of Colorado, Health Sciences Center, Denver, U.S.A. 3. Associate Professor K.C. Srivastava, Department of Environmental Medicine Institute of Community Health, Odense University, Odense, Denmark. 4. Dr. K. Wirth, Hoechst AG, SBU Cardiovascular Agents, Frankfurt (Main), Germany. 5. Professor E.K. Gan, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia. XIII. EXAMINER FOR PH.D. THESES 1. Ph.D. Theses Examiner, Department of Pharmacology, Faculty of Medicine, National University of Malaysia, Kuala Lampur, Malaysia. January 1992. 2. Ph.D. Thesis Examiner, Department of Pharmacology, Faculty of Medicine, National University of Malaysia, Kuala Lumpur, Malaysia. February 1994. XIV. TEACHING Undergraduate (M.D., M.B.Ch.B. and B.Pharm (Hons)). 1. Problem Based Learning and Fixed Modules learning to 2nd and 3rd year M.D. and B. Pharm. (Hons) students in the Integrated System of Education. 2. A course of lectures and tutorials on Physiological and Pharmacological Basis of Therapeutics to 1st , 2nd , and 3rd year, 4th year and 5th year M.D. and B.Pharm. 3. Problem coordinator for Respiratory Block and Coordinator for Central Nervous System to M.D. and B. Pharm. 4. Practical classes on pharmacological experiments. 17
  • 18. Curriculum Vitae of Jagdish N. Sharma 5. Elective topics on non-medical curriculum related subjects and research elective on Advanced Therapeutics for M.D. and B.Pharm. Courses. 6. Pharmacological Basis of Therapeutics of Renal, Respiratory, Blood, Cardiovascular, Central Nervous System, Gastrointestinal System, Autacoids Pharmacology, General Pharmacology, Anti-Microbial, Endocrine Pharmacology, Autonomic Pharmacology, Dermatology and Rheumatology 7. Course coordinator of Applied Therapeutics courses of B. Pharm. Pharmacy programs 432, 531 and 533. 8. Patients Case Based Teaching of Applied Therapeutics to B.Pharm. 432 and 533. 9. Pathophysiology and Chemotherapeutics to B.Pharm. Nursing and Medical Technologists 1. Course of lectures on Pharmacology. 2. Practical classes in experimental pharmacology. Postgraduate 1. Co-coordinator of the Department of Pharmacology to 1st year M.Med. (Master of Medicine) students in Internal Medical, Pediatrics and Surgical Base Disciplines. September 1988 – 1996. 2. Board Member of the Postgraduate Research and Development Committee of the School of Medical Sciences, Universiti Sains Malaysia. July 1988 – 1996. 3. Lectures or courses of lectures to Master of Medicine and Master of Pharmacy students in Medical and Surgical Base Departments. 4. Chairman of the Continuity Medical Education, School of Medical Sciences, Universiti Sains Malaysia. February 1995 to Dec 1996. 5. Supervision of Ph.D. and M.Sc. research projects. 18
  • 19. Curriculum Vitae of Jagdish N. Sharma XV- A. BOOK: 1. Jagdish N. Sharma (2011). “Topics in Mediators Pharmacology” 1st Edition, Nova Science Publishers, Inc., New York, USA 2. Jagdish N. Sharma (2014). Progress in Drug Research: Recent Developments in the Regulation of Kinins (Editor). Volume 69. Editor. Springer International Publisher, Basel, Switzerland. XV-B. FULL PUBLICATIONS: 109. Sharma , J. N. and Narayanan, P. ( 2015 ). Basic pharmacology of bradykinin receptor agonists. Austin Journal of Pharmacology and Therapeutics (USA) 3: 1070 108. Sharma, J. N. , Al-Shoumer, K. A. S., Matar, Madathil, N. V. and Al-Moalem, A.M.K. ( 2015 ). Altered activities of kininsae II, an angiotensin converting enzyme, prekallikrein and nitric oxide in Kuwaiti patients with type 2 diabetes. International Journal of Immunopathology and Pharmacology (Italy) 28: 240-246. 107. Sharma, J. N. (2014). Basic and clinical aspects of bradykinin receptor antagonists. In “ Progress in Drug Research: Recent Developments in the Regulation of Kinins. Volume 69. Edited by J. N. Sharma, Springer International Publisher, Basel, Switzerland. pp. 1-14. 106. Sharma, J. N. and Narayanan, P. (2014). The kallikrein-kinin pathways in hypertension and diabetes.. In “ Progress in Drug Research: Recent Developments in the Regulation of Kinins. Volume 69. Edited by J. N. Sharma, Springer International Publisher, Basel, Switzerland, pp.15-36. 105. Sharma, J. N. , Al-Shoumer, K. A. S., Matar, K. M., Al-Gharee, H. Y. and Madathil, N. V. (2013). Bradykinin-forming components in Kuwaiti patients with type 2 diabetes. International Journal of Immunopathology and Pharmacology (Italy) 26: 699-705 19
  • 20. Curriculum Vitae of Jagdish N. Sharma 104. Sharma, J. N. (2013). The kinin system in hypertensive pathophysiology. Inflammopharmacology (UK) 21: 1-9 103. Sharma, J. N. (2012). Association between the kinin-forming system and cardiovascular pathophysiology. Asia Pacific Journal of Tropical Biomedicine (China) 2 (Supplement 3): S1938-S1944. 102. Sharma, J. N. and Al-Banoon, A. (2012). The role of inflammatory mediator brabykinin in cardiovascular and renal system. Open Access Scientific Report. 1: 142.doi:104172 101. Sharma, J. N. and Narayanan, P. (2011). Hypertension and Diabetes: Contribution of the kallikrein-kinin system. Journal of Diabetes and Metabolism (USA) S4:004. doi:10.4172/2155- 6156. S4-004. 100. Sharma, J. N. and Kesavarao, U. (2011). The effects of captopril on cardiac regression, blood pressure and bradykinin components in diabetic Wistar Kyoto rats. International Journal of Immunopathology and Pharmacology (Italy) 24: 337-343. 99. Sharma, J. N. and Al-Sherif, G. J. (2011). The kinin system: present and future pharmacological targets. American Journal of Biomedical Sciences (USA) 3: 156-169. 98. Sharma, J. N. (2010). Activation of bradykinin system by angiotensin- converting enzyme inhibitors. European Journal of Inflammation (Italy) 8: 55-61. 97. Sharma, J. N. (2010). Modification in tissue kallikrein activity with indomethacin and prednisolone treatment in arthritic rats. Inflammopharmacology (UK) 18: 113-117. 96. Sharma, J. N. (2009). An overview on relation between the bradykinin system and hypertension and diabetes. American Journal of Biomedical Sciences (USA) 1: 242-249. 95. Sharma, J. N. (2009). Hypertension and the bradykinin system. Current Hypertension Reports (USA) 11: 178-181. 94. Sharma , J. N. (2009). The kallikrein-kinin pathways in mediating the 20
  • 21. Curriculum Vitae of Jagdish N. Sharma hypotensive action of angiotensin converting enzyme (ACE) inhibitors. In “ Angiotensin Converting Enzyme Inhibitors” Edited by A. N. DeBrue. Nova Science Publishers (USA) pp. 185-198. 93 Sharma, J. N. (2008). Cardiovascular activities of the bradykinin system. The Scientific World Journal (USA) 8: 384-393. 92. Sharma, J. N., Kadir, Z. and Uma, K. (2008). Evaluation of inflammatory kinin-forming components in experimental epilepsy in rats. Inflammopharmacology (UK) 16: 151-153. 91. Sharma, J. N. (2007). The bradykinin system: role in cardiovascular and and diabetic pathophysiology. Current Topics in Pharmacology (India) 11: 91-100. 90. Sharma, J. N., Al-Omran, A and Parvathy, S. S. (2007). Role of nitric oxide in inflammatory diseases. Inflammopharmacology (U.K.) 15: 252-259 89. Sharma, J. N. and Kesavarao, U. (2007). Changes in plasma prekallikrein activity, blood pressure and left ventricular thickness in hypertensive and normotensive diabetic rats. Methods and Findings in Experimental and Clinical Pharmacology (Spain) 29: 75- 78. 88. Sharma, J. N. (2007). The kinin-forming system and cardiovascular disorders. Journal Salud (i) Ciencia (Argentina) 15: 972-976. 87 . Sharma, J. N. and Al-Sherif, G. J. (2006). Pharmacologic targets and prototype therapeutics in the kallikrein-kinin system: Bradykinin receptor agonists or antagonists. The Scientific World Journal (USA) 6: 1247-1267. 86 Sharma, J. N. and Abbas, S. A. (2006). Effect of captopril in the presence of Kinin B2-receptor antagonist on the duration of survival after prolonged coronary artery ligation in hypertensive rats. Methods and Findings in Experimental and Clinical Pharmacology (Spain) 28: 217-221. 85 Sharma, J. N. (2006). Is there a place for bradykinin agonists in therapy of 21
  • 22. Curriculum Vitae of Jagdish N. Sharma cardiovascular disorders? Journal of Pharmacology and Toxicology (USA) 1: 12-18. 84 Sharma, J. N. and Mohammed, L. A. (2006). The role of leukotrienes in pathophysiology of inflammatory disorders: Is there a case for revisiting leukotrienes as therapeutic targets? Inflammopharmacology (UK) 14: 10-16. 83 Sharma, J. N. (2006). Role of tissue kallikrein-kininogen-kinin pathways in cardiovascular system. Archives of Medical Research (USA) 37: 299-306 . 82 Sharma, J. N. and Jawad, N. M. (2005). Adverse effects of COX-2 inhibitors. The Scientific World Journal (USA) 5: 629-645. 81 Sharma, J. N. and Abbas, S. A. (2005). A bradykinin antagonist abolishes beneficial effect of captorpril on duration of survival after acute coronary artery ligation in hypertensive rats. Pharmacological Research (UK) 52: 211-215. 80 Sharma, J. N. (2005). The kallikrein-kinin system: From mediator of inflammation to modulator of cardioprotection. Inflammopharmacology (UK) 12: 591-596. 79 Sharma, J. N. and Thani R. B. (2004). Therapeutic prospects of bradykinin receptor agonists in the treatment of cardiovascular diseases. Investigational Drugs Journal (IDrugs) (UK) 7: 926-934 78 Sharma, J. N. (2004). Bradykinin agonists in the treatment of cardiovascular disorders. In the “Proceeding of the 20th Federation of the Asian Pharmaceutical Association (FAPA) Congress; Edited by Srianujata, S.; Bangkok, Thailand. pp 1-6. 77 Sharma, J. N., Samud, A. M. and Asmawi, M. Z. (2004). Comparison between plethysmometer and micrometer methods to measure acute paw oedema for scrining ant-inflammatory activity in mice. Inflammopharmacology (UK) 12: 89-94 76 Sharma, J. N., Abbas, S. A., Yusof, A. P. M., Shah, R. P. and Gan, E. K. (2004). Tissue kallikrein increases survival after prolonged coronary artery ligation in hypertensive rats. Pharmacology (Basel) 70: 201-205 22
  • 23. Curriculum Vitae of Jagdish N. Sharma 75 Sharma, J. N. (2003). Does the kinin system mediate in cardiovascular abnormalities? An overview. The Journal of Clinical Pharmacology (USA) 43: 1187-1195. 74 Sharma, J. N. and Al-Dhalmawi, G. (2003). Bradykinin receptor antagonists: therapeutic implications. Investigational Drugs Journal (IDrugs) (UK) 6: 581-586. 73 Sharma, J. N., Abbas, S. A., Yusof, A. P. M. and Shah, R. P. (2003). Evaluation of tissue kallikrein activity on survival time after acute coronary artery ligation in hypertensive rats. International Immunopharmacology (USA) 3: 329-334. 72 Sharma, J. N. and Uma, K. (2002). Effect of Captopril on Urinary Kallikrein, Blood Pressure and Myocardial Hypertrophy in Diabetic Spontaneously Hypertensive Rats. Pharmacology (Basel) 64: 196- 200. 71 Sharma, J. N. and Sharma, J. (2002). Cardiovascular Properties of the Kallikrien- Kinin System. Current Medical Research and Opinion (Lond.) 18: 10- 17. 70 Sharma, J. N., Zubaid, M., Khan, B. Z. S. J., Yusof, A.P.M. and Asmawi, M. Z. (2000). Pathophysiological activities of the Kallikrien- Kinin System with emphasis on the cardiovascular disorders. Inflammopharmacology (UK) 8: 219- 241. 69 Sharma, J. N. (2000). Kinin System in Protecting the Heart. In “National Symposium on Health Sciences Proceeding”, Edited by K.L. Yap et al. Kuala Lumpur, Malaysia. PP. 381- 384. 68 Sharma, J. N., Kesavarao, U. and Yusof, A.P.M. (1999). Altered Cardiac Tissue and Plasma Kininogen levels in Hypertensive and Diabetic Rats. Immunopharmacology 43: 129- 132. 67 Abbas, S.A., Sharma, J.N. and Yusof, A.P.M. (1999). The Effect of Bradykinin and Its Antagonist on Survival Time After Coronary Artery Occlusion in Hypertensive Rats. Immunopharmacology (The Netherlands). 44: 93 – 98. 66 Samud, A.M., Asmawi, M.Z., Sharma, J.N. and Yusof, A.P.M. (1999). Anti-inflammatory Activity of Cranum Asiaticum Plant and Its Effect on Bradykinin Induced Contractions on Isolated Uterus. Immunopharmacology. (The Netherlands). 43: 311 – 316. 23
  • 24. Curriculum Vitae of Jagdish N. Sharma 65 Abbas, S.A., Sharma, J.N. and Yusof, A.P.M. (1999). Effect of Bradykinin and Its Antagonist on Survival Time After Coronary Artery Occlusion in Rats. General Pharmacology (USA). 33: 243 – 247. 64 Sharma, J.N. and Yusof, A.P.M. (1998). Proinflammatory Properties of the Kallikrein – Kinin System: Potential for new Drugs Therapy. Inflammopharmacology (The Netherlands) 6: 286 – 296. 63 Akbar, A., Sharma, J.N., Yusof, A.P.M. and Gan, E.K. (1998). Potentiation of Bradykinin Induced Responses by Indomethacin in Intact and Denuded Epithelium of Guinea-Pig Tracheal Preparations. International Journal of Tissue Reactions (Geneva). XX: 95 – 100. 62 Sharma, J.N., Uma, K. and Yusof, A.P.M. (1998). Left Ventricular Hypertrophy and Its Relation to Cardiac Kinin-Forming System in Hypertensive and Diabetic rats. International Journal of Cardiology (U.K.) 63: 229 – 235. 61 Sharma, J.N., Yusof, A.P.M. and Wirth, K.J. (1998). The Kinin antagonist Hoe 140 Reduces Paw Oedema in rats Caused by Carrageenan, Bradykinin and Kaolin. Inflammopharmacology (The Netherlands) 6: 9 – 17. 60 Sharma, J.N., Yusof, A.P.M. and Ishak, F.I. (1997). Significance of the Kinin System in Pathophysiology of Inflammatory Joint Diseases. In “Proceedings of the 16th Asian Congress of Pharmaceutical Sciences”. Edited by Hussin, A.H., Ibrahim, M.I.M. and Awang, R. Malaysian Pharmaceutical Society, Kuala Lumpur, pp. 140 – 145. 59 Sharma, J.N., Ishak, F.I., Yusof, A.P.M. and Srivastava, K.C. (1997). Effects of Eugenol and Ginger Oil on Adjuvant Arthritis and the Kallikrein in Rats. Asia Pacific Journal of Pharmacology (Singapore) 12: 9 – 14. 58 Sharma, J.N. and Yusof, A.P.M. (1997). Cardioprotective Effects of Kinin System and its role in Inflammation. International Journal of Tissue Reactions (Geneva) 19: 53. 57 Sharma, J.N. and Kesavarao, U. (1996). Cardiac Kallikrien in Hypertensive and Normotensive Rats with and without Diabetes. Immunopharmacology (The Netherlands) 33: 341 – 343. 24
  • 25. Curriculum Vitae of Jagdish N. Sharma 56 Sharma, J.N. and Wirth, K.J. (1996). Inhibition of rats Adjuvant Arthritis by a Bradykinin Antagonist Hoe 140 and its Influence on Kallikrein. General Pharmacology (U.S.A.) 27: 133 – 136. 55 Sharma, J.N., Uma, K., Noor, A.R. and Rahman, A.R. (1996). Blood Pressure Regulation by the Kallikrein-Kinin System. General Pharmacology (U.S.A.) 27: 55 – 65. 54 Sharma, J.N., Amrah, S.S. and Noor, A.R. (1995). Suppression of Hypotensive Responses of Captopril and Enalapril by kallikrein Inhibitor Aprotinin in Spontaneously Hypertensive Rats. Pharmacology (Basel) 50: 363 – 369. 53 Sharma, J.N., Srivastava, K.C. and Gan, E.K. (1994). Suppressive Effects of Eugenol and Ginger Oil on Arthritic Rats. Pharmacology (Basel) 49: 314 – 318. 52 Sharma, J.N., Amrah, S.S. and Srivastava, K.C. (1994). Anti-inflammatory Properties of Eugenol and Ginger Oil in Rat Arthritis Induced by Mycobacterial Adjuvant. In “Trends in Traditional Medicine Research”. Edited by Chan, K.L., Hussin, A.H., Yuen, K.H., Asmawi, M.Z. and Ismail, Z., School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia. pp.298 – 302. 51 Sharma, J.N. and Buchanan, W.W. (1994). Pathogenic Responses of Bradykinin System in Chronic Inflammatory Rheumatoid Disease. Experimental and Toxicologic Pathology (Germany) 46: 421 – 433. 50 Sharma, J.N. (1993). Therapeutic Prospects of Bradykinin Receptor Antagonists. General Pharmacology (Lond.) 24: 267 – 274. 49 Sharma, J.N., Stewart, J.M., Mohsin, S.S.J., Katori, M. and Vavrek, R. (1992). Influence of a Kinin Antagionist on Acute Hypotensive Responses Induced by Bradykinin and Captopril in Spontaneously Hypertensive Rats. Agents and Actions 38 (Suppl.III): 258 – 269. 48 Sharma, J.N. (1992). Involvement of the Kinin – Forming System in the Physiopathology of Rheumatoid Inflammation. Agents and Actions 38 (Suppl. III): 343 – 361. 25
  • 26. Curriculum Vitae of Jagdish N. Sharma 47 Mohsin, S.S.J, Majima, M., katori, M. and Sharma, J.N. (1992). Important Suppressive Roles of the kallikrein – Kinin System During the Developmental Stage of Hypertension in the Spontaneously Hypertensive Rats. Asia Pacific Journal of Pharmacology (Singapore) 7: 73 – 82. 46 Akbar, A. and Sharma, J.N. (1992). Influence of Indomethacin on Histamine –and- Acetylcholine- Induced Responses in the Intact and Denuded Epithelium of Guinea – Pig Tracheal Smooth Muscle. Pharmacological Research (Lond.). 25: 279 – 286. 45 Sharma, J.N. (1991). Pro-Inflammatory Actions of Platelet Activating Factor: Relevant to Joint Inflammatory disease. Experimental Pathology (Jena) 43: 47 – 50. 44 Sharma, J.N. (1991). The Role of Kinin System in Joint Inflammatory Disease. European Journal of Rheumatology and Inflammation (Lond.) 11: 30 – 36. 43 Sharma, J.N. (1991). The Role of Kallikrein –Kinin System in Joint Inflammatory Disease. Pharmacological Research (Lond.) 23: 105 – 112. 42 Sharma, J.N. (1990). Does Kinin Mediate the Hypotensive Action of Angiotensin Converting Enzyme (ACE) Inhibitors? General Pharmacology (Lond.) 21: 451 – 457. 41 Sharma, J.N. and Mohsin, S.S.J. (1990). The Role of Chemical mediators in Pathogenesis of Inflammation with Emphasis on the Kinin System. Experimental Pathology (Jena) 38: 73 – 96. 40 Sharma, J.N. (1989). Contribution of Kinin System to the Antihypertensive Action of Angiotensin Converting Enzyme Inhibitors. Advances in Experimental Medicine and Biology (New York) 247A: 197 – 205. 39 Sharma, J.N. (1988). The Kinin System and Prostaglandins in the Intestine. Pharmacology and Toxicology (Acta Pharmacologica et Toxicologica) (Copenhagen) 63: 310 – 316. 38 Sharma, J.N., Zeitliln, I.J., Mackenzie, J.F. and Russell, R.I. (1988). Plasma Kinin – Precursor levels in Clinical Intestinal Inflammation. Fundamental and Clinical Pharmacology (Paris) 2: 399 – 403. 26
  • 27. Curriculum Vitae of Jagdish N. Sharma 37 Sharma, J.N., (1988). The Kallikrein –Kinin System and Hypertension in “Renal Function, Hypertension and Kallikrein – Kinin System”. Edited by limura, O. and Margolius, H.S. University of Tokyo Press, Tokyo, pp. 147 – 154. 36 Sharma, J.N. (1988). Interrelationship Between the Kallikrein-Kinin System and Hypertension. A review, General Pharmacology (Lond.)19: 177 – 187. 35 Alhaboui, H.A., Bennett, D., Sharma, J.N., Thomas, G.R. and Zeitliln, I.J. (1986). A Synovial Amidase Acting on Tissue Kallikrein- Selective Substrate in Clinical and Experimental Arthritis. Advances in Experimental Medicine and Biology (New York) 198B: 405 – 411. 34 Sharma, J.N. (1986). Kallilkrein – Kinin System and Prostaglandin Interactions: Relevant to hypertension. Pharmacological Research Communications (Lond.) 18: 639 – 652. 33 Sharma, J.N. (1984). Kinin –forming System in the Genesis of Hypertension. Agents and Actions (Basel) 14: 200 – 205. 32 Sharma, J.N., Fernandez, P.G. and Triggle, C.R. (1984). The Effect of Indomethacin on the duration of Hypotensive Action of Bradykinin in Dahl Salt – Resistant Rats: Role of cyclo-oxygenase inhibition. Prostaglandins Leukotrienes and Medicine (Edinburgh) 14: 131 – 135. 31 Sharma, J.N., Fernandez, P.G., Laher I. And Triggle C.R. (1984). Differential Sensitivity of Dahl Salt – Sensitivity and Salt – Resistant rats to the Hypotensive Action of Acute Nifedipine Administration. Canadian Journal of Physiology and Pharmacology 62: 241 – 243. 30 Sharma, J.N., Fernandez, P.G., Kim, B.K. and Triggle, C.R. (1984). Systolic Blood pressure Responses to Enalapril Maleate (MK – 421), an angiotensin converting enzyme inhibitor and Hydrochlorothiazide in Conscious Dahl Salt Sensitive (S) and Resistant (R) Rats. Canadian Journal of Physiology and Pharmacology 62:846 – 849. 29 Sharma, J.N. (1983). Ability of Prostaglandins to induce Acute Inflammatory Bowel Disease in the Rats. A preliminary report. Journal of Medicine (New York) 14: 157 – 160. 27
  • 28. Curriculum Vitae of Jagdish N. Sharma 28 Fernandez, P.G., Kim, B.K., Galway, A.B. and Sharma, J.N. (1983). Separation of Essential Hypertensive Patients based on Blood Pressure Responses after the withdrawal of Antihypertensive Agent by Stepwise Discriminent Analysis. Current Medical Research and Opinion (Lond.) 8: 509 – 517. 27 Sharma, J.N., Fernandez, P.G., Kim, B.K., Edikio, H. and Triggle, C.R. (1983). Cardiac Regression and Blood pressure Control in the Dahl Rat Treated with Enalapril Maleate (MK – 421), an angiotensin converting enzyme. Journal of Hypertension (Lond.) 1: 251 – 256. 26 Sharma, J.N., Zeitlin, I.J., Deodhar, S.D. and Buchanan, W.W. (1983). Detection of Kallikrein-Like Activity in Inflamed Synovial Tissue. Archives Internationales de Pharmacodynamie et de Therapie (Ghent) 262: 279 – 286. 25 Fernandez, P.G., Sharma, J.N., Galway, A.B., Campbell, N., Kim, B.K., Snedden, W., Granter, S., MacDonald, J. and Gill, V. (1982). Potassium Conservation with Amiloride Hydrochlorothiazide (Modurate) in Thiazide Induced Hypokalemia in Hypertension. Current Medical Research and Opinion (Lond.) 8: 120 – 127. 24 Snedden, W., Sharma, J.N. and Fernandez, P.G. (1982). A sensitive Assay Method of Furosemide in Plasma and Urine by High-Performance Liquid Chromatography. Therapeutic Drug Monitoring (New York) 4: 831 – 383 23 Fernandez, P.G., Sharma, J.N., Gallway, A.B., Kim, B.K., Granter, S. and Zachariah, P.K. (1982). Comparison of Antihypertensive Efficacy: Propanolol Verses Oxprenolol in Accelerated Hypertension. Pharmatherapeutica (Lond.) 3: 153 – 156. 22 Sharma, J.N. and Fernandez, P.G. (1982). Pharmacological Abnormality of the Kallikrein-Kinin System in Hypertension. Medical Hypothesis (Edinburgh) 9: 379 – 384. 21 Sharma, J.N. and Zeitlin, I.J. (1982). Reduced Plasma Kininogen Concentration by Prostaglandin E2 in rats. European Journal of Pharmacology (Amsterdam) 83: 119 – 121. 20 Sharma, J.N. and Zeitlin, I.J. (1981). Altered Plasma Kininogen in Clinical Hypertension. 28
  • 29. Curriculum Vitae of Jagdish N. Sharma Lancet (Lond.) 1: 1259 – 1260. 19 Sharma, J.N., Zeitlin, I.J., Brooks, P.M., Buchanan, W.W. and Dick, W.C. (1980). The Action of Aspirin on Plasma Kininogen and Other Proteins in Rheumatoid Patients. Clinical and Experimental Pharmacology and Physiology (Oxford) 7: 347 – 354. 18 Sharma, J.N. and Buchanan, W.W (1980). Some Modern Aspects of the Mode of Action of Non-steroidal Anti-inflammatory Drugs. Pharmatherapeutica (Lond.) 2: 387 – 396. 17 Sharma, J.N. and Buchanan, W.W. (1979). Kinin System in clinical and Experimental Rheumatoid Inflammation: Short review. Current Medical Research and Opinion (Lond.) 6: 314 – 321. 16 Sharma, J.N. (1978). The Effect of Prostaglandins (PGE2 and PGF2) on Plasma Kininogens Levels in the Rat. Biomedicine (Paris) 29: 292 – 293. 15 Sharma, J.N. and Zeitlin, I.J. (1977). Indomethacin in Low Concentration Potentiates the Action of Some Spasmogens on the isolated Oestrous Rat Uterus. Journal of Pharmacy and Pharmacology (Lond.) 29: 316 – 317. 14 Sharma, J.N. (1977). Changes in Biochemical Parameters Associated with Experimental Arthritis in Rabbits. Biomedicine (The European Journal of Clinical and Biological Research) (Paris) 27: 252 – 255. 13 Sharma J.N. and Sharma, J.N (1977). Comparison of Anti-inflammatory Activity of Commiphora Mukul (an indigenous drug) with Phenylbutazone and Ibuprofen in Experimental Arthritis Induced by Mycobacterial Adjuvant. Arzeneimittel Forschung (Drug Research) (Germany) 27: 1455 – 1457. 12 Sturrock, R.D., Sharma, J.N. and Buchanan, W.W. (1977). Evidence of Rheumatoid Arthritis in Ancient India. Arthritis and Rheumatism (U.S.A) 20: 42 – 44. 11 Zeitlin, I.J., Sharma, J.N., Brooks, P.M. and Dick, W.C. (1977). An Effect of Indomethacin on raised Plasma Kininogen Levels in Rheumatoid Patients, In “Chemistry and Biology of the Kallikrein – Kinin System in Health and Disease”. Edited by Pisano, J.J. and Austen, K.F. United States Government Printing Office, Washington, D.C., pp. 483 – 486. 29
  • 30. Curriculum Vitae of Jagdish N. Sharma 10 Sharma, J.N., (1976). Studies on Plasma Kinin Precursors in Rheumatoid Arthritis. Ph.D. Thesis. The University of Strathclyde, Glasgow, Scotland, U.K. 9 Zeitlin, I.J., Sharma, J.N., Brooks, P.M. and Dick W.C. (1976). Raised Plasma Kininogen levels in Rheumatoid Arthritis: Response to Therapy with Non-Steroidal Anti- inflammatory Drugs. Advances in Experimental Medicine and Biology (New York) 70: 335 – 343. 8 Sharma, J.N., Zeitlin, I.J., Brooks, P.M. and Dick, W.C. (1976). A Novel Relationship Between Plasma Kininogen and Rheumatoid Diseases. Agents and Actions (Basel) 6: 148 – 153. 7 Sharma, J.N., Zeitlin, I.J., Brooks, P.M. and Dick, W.C., (1975). Raised Plasma Kininogen Levels in Rheumatoid Arthritis: Response to Idomethacin and Relationship to clinical Indices. Annals of Rheumatic Diseases (Lond) 34: 464. 6 Brooks, P.M., Dick, W.C., Sharma, J.N. and Zeitlin, I.J. (1974). Changes in Plasma Kininogen Levels Associated with Rheumatoid Arthritis. British Journal of Clinical Pharmacology 1: 351 P 5 Sharma, J.N. Sharma, J.N. and Arora, R.B. (1973). Abnormal Pattern of Serum Proteins and Alkaline Phosphatase Activity in Rheumatoid Arthritis and Indication of Liver Dysfunction. Rheumatism 8: 142 – 147. 4 Sharma, J.N., Sharma, J.N and Arora, R.B. (1973). Arthritis and Liver Function. Rheumatism 8: 119 – 128. 3 Sharma, J.N. (1972). Liver Functions is arthritis and their Modification Drugs: An Experimental and Clinical Study. M. Sc. (Pharmacology) Thesis. The All India Institute of Medical Sciences, New Delhi, India. 2 Sharma, J.N., Sharma J.N., Shastri H.D. and Arora, R.B. (1972). Beneficial Effect of Fraction A of Gum Guggal in Arthritis. A clinical appraisal. Rheumatism. 8: 21 – 53 1 Sharma, J.N., Sharma, J.N. and Arora, R.B. (1972). Beneficial Effect of fraction A of Gum Guggal in Arthritis and Liver Functions in Clinical and Experimental Arthritis. Rheumatism (New Delhi) 7: 20 – 21. 30
  • 31. Curriculum Vitae of Jagdish N. Sharma XVI. ABSTRACTS AND PRESENTATIONS IN INTERNATIONAL AND NATIONAL CONFRENCES: 1. Zeitlin, I. J., Sharma, J. N., Brooks, P. M. and Dick, W. C. (1974). An Effect of Indomethacin on Raised Plasma Kininogen Levels in Rheumatoid Patients. Paper presented in the Conference on “Chemistry and Biology of the Kallikrien- Kinin System in Health and Disease”. Organized by the Fogarty International Center for Advanced Study in the Health Sciences and the National Institute of Health, Bethesda, Maryland, U. S. A. October 20- 23. 2. Brooks, P. M., Sharma, J. N., Zeitlin, I. J. and Dick, W. C. (1975). Plasma Kininogen and Rheumatoid Disease. Scandinavian Journal of Rheumatology 4 (Suppl. 8): Abstract No. 094. 3. Zeitlin, I. J., Sharma, J. N., Brooks, P. M., and Dick, W. C. (1976). Raised Plasma Kininogen- Levels in Rheumatoid Patients- Response to Therapy with Nonsteroidal Anti- Inflammatory Drugs. Agents and Actions 6: 449. 4. Zeitlin, I. J., Sharma, J. N., Brooks, P. M., Dick, W. C., Mackenzie, J. F., Russell, R. I., Strong, A. M. and Thomson, J. (1977). Changes in Plasma Kininogen Levels Associated with Inflammatory Diseases. Scottish Medical Journal 22: 191. 5. Zeitlin, I. J., Sharma, J. N., Brooks, P. M. and Dick, W. C. (1978). Studies on the Systematic Kinin System in Rheumatoid Arthritis. International Congress of Inflammation, Bologna, Italy, pp. 198. 6. Sharma, J. N. (1980). Does Prostaglandin E2 Cause Release of Plasma Kinins in the Rat? Arachidonic Acid Cascade Symposium (European Society of Biochemical Pharmacology), Seventh Congress of the Polish Pharmacological Society, pp. 205. 31
  • 32. Curriculum Vitae of Jagdish N. Sharma 7. Sharma, J. N., Fernandez, P. G., Kim, B. K., Triggle, C. R., Idikio, H. and Laher, I. (1983). Blood Pressure control and Hypertensive Heart Changes in the Dahl (D) Rat: MK- 421 (an angiotensin converting Enzyme inhibitor) Versus Hydrochlorothiazide. Clinical research 31: 335A. 8. Sharma, J. N., Fernandez, P. G., Kim, B. K., and Triggle, C. R. (1983). Antihypertensive Efficacy of MK- 241 (an angiotensin converting enzyme inhibitor, ACEI) and Hydrochlorothiazide (HTZ) in Conscious Dahl Sensitive (S) and Resistant (R) Rats. Clinical Research 31: 335A. 9. Fenandez, P. G., Sharma, J. N., Kim, B. K., Triggle, C. R., Idikio, H. and Laher, I. (1983). Left Ventricular Regression and Blood Pressure Control on the Dahl (D) Rat with MK- 421 (an angiotensin converting enzyme inhibitor, ACEI) and Hydrochlorothiazide (HTZ). Clinical Research 31: 332A. 10. Fernandez, P. G., Kim, B. K., Sharma, J. N., Indikio, H. and Triggle, C. R. (1983). Left Ventricular Regression (LVR) in association with Blood Pressure Control in the Dahl Model of Hypertensive Rats (DS and DR) Treated with Enalpril Maleate (MK- 241) (an angiotensin converting enzyme inhibitor) or Hydrochlorothiazide (HTZ). Clinical and Investigative Medicine 6 (Suppl. 2): 55. 11. Alhaboubi, A. H., Bannett, D., Sharma, J. N., Thomas, G. R. and Zeitlin, I. J. (1984). A Synovial Amidase Acting on Tissue Kallikrein- Selective Substrate in Clinical Experimental Arthritis. Presented in the International Kinin Conference, Savannah, GA 30912, U. S. A. 12. Sharma, J. N., (1987). Contribution of Kinin System to the Anti- Hypertensive Action of Angiotensin Converting Enzyme Inhibitors (ACEIs). Kinin 1987 Tokyo International Congress, pp. 25 (a- 1- 08). 13. Sharma, J. N. (1987). The Kallikrein- Kinin System and Hypertension. Satellite Symposiums of International Kinin Congress in Sapporo, Japan, pp. 33. 32
  • 33. Curriculum Vitae of Jagdish N. Sharma 14. Sharma, J. N. (1989). The Kallikrein- Kinin System (KKS) in Joint Inflammatory Disease. 3rd Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Monte Carlo, pp. 26. 15. Sharma, J. N. (1989). The Kinin System in Hypertension and Inflammation Malaysian Society of Pharmacology and Physiology, Penang, Malaysia. Abstract of Special Lecture pp. S1- S2. 16. Sharma, J. N., Mohsin, S. S. J., Stewart, J. M., Vavrek, R. and Lockman, A. (1989). The Effect of a New Synthetic Antagonist to Bradykinin (BK) on Acute Antihypertensive Action of Captopril in Spontaneously Hypertensive Rats (SHR). Malaysian Society of Pharmacology and Physiology, Penang, Malaysia. Abstract pp. C24. 17. A. Akbar, Sharma, J. N. and Mohsin, S. S. J. (1989). Influence of the Epithelium on Responsiveness of Isolated Guinea- Pig Tracheal of Agents. Malaysian Society of Pharmacology and Physiology, Penang, Malaysia. Abstract pp. C8. 18. Mohsin, S. S. J. and Sharma, J. N. (1989). Does the Kidney Release Hypotensive Substance? Malaysian Society of Pharmacology and Physiology, Penang, Malaysia. Abstract pp. C20. 19. Sharma, J. N. (1991). Participation of the Kallikrien- Kinin System in the Pathogenesis of Inflammatory Joint Disease. 4th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 66. 20. Sharma, J. N. (1991). Involvement of Kinin- Forming System in the Physiopathology of Rheumatoid Inflammation. International Kinin conference towards Understanding the Molecular Basis of Kinin Action, Munich. Abstract pp. 167. 21. Sharma, J. N., Stewart, J. M., Mohsin, S. S. J., Katori, M. and Vavrek, R. (1991). Influence of a Kinin Antogonist on Acute Hypotensive Responses Induced by Bradykinin and Captopril in Spontaneously Hypertensive Rats. International Kinin Conference Towards Understanding the Molecular Basis of Kinin Action, Munich. Abstract pp. 346. 33
  • 34. Curriculum Vitae of Jagdish N. Sharma 22. Sharma, J. N. (1993). Tissue and Plasma Kallikreins Activities in the Regulation of Adjuvant Arthritis in Rats. Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 183. 23. Sharma, J. N. (1993). Inhibition of Adjuvant Inflammation in Rats by the Kinin Receptor Antagonist Hoe 140. Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 184. 24. Sharma, J. N., Srivastava, K. C. and Mustafa, T. (1993). Ginger (Zingibar officinale) in Rheumatism and Musculoskeletal Disorders. 5th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 123. 25. Sharma, J. N. (1993). The Role of Kallikrein- Kinin System in Hypertensive Disease. Guest Lecture of the 11th Iranian Congress of Physiology and Pharmacology. Tabriz University of Medical Sciences, Tabriz, Iran. Abstract No. L- 7. 26. Sharma, J. N. and Mohsin, S. S. J. (1993). Effect of a Bradykinin Antagonist on Adjuvant Arthritis in Rats. 10th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology. Kelantan. Abstract No. A6. Asian Pacific Journal of Pharmacology 8 (Suppl. 2): S23. 27. Sharma, J. N. and Srivastave, K. C. (1993). Anti- inflammatory Properties of Eugenol and Ginger Oil in Rats Arthritis Induces by Mycobacterial Adjuvant. The International Conference on the Use of Traditional Medicine and Other Natural Products in Health- Care, Penang, Malaysia. Abstract No. OA- 2. 28. Sharma, J. N. (1993). Alterations in Kallikreins Levels in Experimental Arthritis in Rats. International Kinin Conference, Guaruja, Brazil. Abstract No. 9. 07. 29. Sharma, J. N. (1993). Altered Blood Pressure Responses to Converting Enzyme Inhibition with Aprotinin- Induced Kallikrein- Kinin System Blockade in Spontaneously Hypertensive Rats. International Kinin Conference, Guaruja, Brazil. Abstract No. 8. 12. 34
  • 35. Curriculum Vitae of Jagdish N. Sharma 30. Sharma, J. N. (1993). Anti- inflammatory Activity of a Bardykinin Antagonist (Hoe 140) in Rats Experimental Arthritis. International Kinin Conference, Guaruja, Brazil. Abstract No. 9. 06. 31. Sharma, J. N. (1994). Changes in Kallikreins Levels Associated with Adjuvant Arthritis in Rats. Satellite Symposia of the XIIth International Union of Pharmacology Congress, Montreal, Canada. Canadian Journal of Physiology & Pharmacology 72 (Suppl. 2): P1. 15, pp. 39. 32. Sharma, J. N. (1994). Suppression of Hypotensive Responses of Captopril and Enalapril by Kallikrien Inhibitor in Hypertensive Rats. Satellite Symposia of the XIIth International Union of Pharmacology Congress, Montreal, Canada. Canadian Journal of Physiology & Pharmacology 72 (Suppl. 2): P1. 14, pp. 39. 33. Sharma, J. N. (1995). Prospect of Kinin Receptor Antagonist as Novel Antirheumatic Drug. 6th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 35. 34. Uma, K., Sharma, J. N. and Noor, A. R. (1995). Importance of Kinin System in Preventing Left Ventricular Hypertrophy in Diabetic and Hypertensive Rats. 6th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 33. 35. Kadir, Z., Sharma, J. N., Uma, K. and Sulaiman, S. A. (1995). Changes in Kallikrein- Kinin System in Experimental Epilepsy in Rats. 6th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunomodulators, Geneva, Switzerland. Abstract No. 34. 36. Sharma, J. N. and Uma, K. (1995). Effect of Captopril on Kallikrein- Kinin System in Hypertensive and Normotensive Rats with and without Diabetes. 14th International Symposium on Kinins, Denver, September 1995. Abstract No. C51. 35
  • 36. Curriculum Vitae of Jagdish N. Sharma 37. Uma, K. and Sharma, J. N. (1995). Changes in Cardiac and Renal Kallikrein- Kinin System in Hypertensive and Normotensive Rats with and without Diabetes. 14th International Symposium on Kinins, Denver, September 1995. Abstract No. C47. 38. Akbar, A., Sharma, J. N. and Gan, E. K. (1995). Effect of Indomethacin on Bradykinin- Induced Responses in the Guinea- Pig Tracheal Smooth Muscle. 14th International Symposium on Kinins, Denver, September 1995. Abstract No. C33. 39. Sharma, J. N., Yusof, A. P. M. and Ishak, F. I. (1996). Significance of the Kinin System in Pathophysiology of Inflammatory Joint Disease. 16th Asian Congress of Pharmaceutical Sciences, Kuala Lumpur, Malaysia, November 1996. Abstract No. A- 14. 40. Sharma, J. N., Yusof, A. P. M. and Ishak, F. I. and Srivastava, K. C. (1997). Suppressive Effects of Eugenol and Ginger Oil on Arthritic Rats: Possible Role of Kallkrein. 7th Intersciences World Conference on Inflammation, Antirheumatics, Analgesics, Immunodulators, Geneva, Switzerland, May 1997. International Journal of Tissue Reactions 19: 54. 41. Sharma, J. N., Uma, K. and Yusof, A. P. M. (1998). Altered Tissue and Plasma Kininogen Levels in Hypertensive and Diabetic Rats. 15th International Conference on Kinins, Nara, Japan, October 1998. Abstract No. O- V- 3 (pp. 71). 42. Abbas, S. A., Sharma, J. N. and Yusof, A. P. M. (1998). The Effect of Bradykinin and Its Antagonist on Survival Time After Coronary Artery Occlusion in Hypertensive and Normotensive Rats. 15th International Conference on Kinins, Nara, Japan, October 1998. Abstract No. P- 14 (pp. 83). 43. Samud, A. M., Asmawi, M. Z. and Sharma, J. N. (1998). Anti- inflammatory Activity of Crinum Asiaticum Plant and Its Effect on Bradykinin Induced Contractions on Isolated Uterus. 15th International Conference on Kinins, Nara, Japan, October 1998. Abstract No. P- X- 18 (pp. 145). 44. Abbas, S. A., Sharma, J. N., Yusof, A. P. M. and Shah, R. P. (1999). The Effect of Tissue Kallikrein and Captopril on Survival Time After Coronary Artery Ligation in 36
  • 37. Curriculum Vitae of Jagdish N. Sharma Spontaneously Hypertensive Rats. 14th Meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, May 1999. Abstract No. OR6. 45. Asmawi, M. Z., Samud, A. M., Sharma, J. N., Yusof, A. P. M. (1999). Anti- inflammatory Activity of the Fractional Extract of Plant Crinum Asiaticum, 14th Meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, May 1999. Abstract No. OR 11. 46. Abbas, A. S., Sharma, J. N., Yusof, A. P. M., Das P. K. and Shah, R. P. (1999). The Effect of Bradykinin on Cardiac Morphology on Normotensive and Hypertensive Rats. 14th Meeting of the Malaysian Pharmacology and Physiology, Penang, Malaysia, May 1999. Abstract No. P1. 47. Sharma, J. N. (2000). Kinin System in Protecting the Heart. National Symposium on Health Sciences, Kuala Lumpur, Malaysia, April 2000. Abstract No 80. 48. Sharma, J. N., Abbas, S. A., Yusof, A. P. M. and Shah, R. P. (2002). Evaluation of tissue kallikrein and captopril activities on survival time after coronary artery ligation in hypertensive rats. Kinin 2002: The 16th International Conference, Charleston, SC, USA, May 26- 31, 2002. Abstract No. O-68. 49. Sharma, J. N. (2003). Recent advances in the kallikrein-kinin system in inflammatory disorders. International Conference on Inflammopharmacology 2003, Royal College of Physicians of Edinburgh, UK, April 22-24, 2003. Inflammopharmacology Abstract No. 36 (pp.56-57). 50. Sharma, J. N. (2003). Significance of the kinin system in the cardiovascular disorders. 7th International symposium on Pharmaceutical Sciences, Ankara University Faculty of Pharmacy, Ankara, Turkey, June 24-27, 2003. Proceeding Abstract No. PL-29 (pp.96-98). 51. Sharma, J. N. (2004). The kallikrein-kinin system in cardiovascular disorders- a new therapeutic modality found? The Philippines Society of Experimental and Clinical Pharmacology Meeting, Manila, Philippines, May 7, 2004. 37
  • 38. Curriculum Vitae of Jagdish N. Sharma 52. Sharma, J. N. (2004). Bradykinin agonists in the treatment of cardiovascular disorders. The 20th Federation of Asian Pharmaceutical Association Congress, Bangkok, Thailand, November 30 –December 3, 2004. Proceeding Abstract pp. 207. 53. Sharma, J. N. (2005). The role of nutraceuticals in therapeutics: myth or reality. The 20th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, April 25-27, 2005, Proceeding Abstract pp 1. 54. Sharma, J. N., Kadir, Z and Uma, K . (2007). Evaluation of the kinin-forming components in experimental epilepsy in rats. KININ 2007, 2nd International Conference on Exporing the Future of Vascular and Inflammatory mediators, Berlin, Germany, May 30-June 2, 2007. Proceeding Abstract P61, pp.119. 55. Sharma, J. N. and Abbas, S. A. (2008). Effect of bradykinin antagonist on beneficial effect of captopril on duration of survival after acute coronary artery ligation in hypertensive rats. The IXth World conference on Clinical Pharmacology and Therapeutics, Quebec, Canada, July 27-August 1, 2008. Proceeding abstract No. T2TH041. 56. Sharma, J. N. and Uma, K. (2009). Effect of captopril on cardiac wall thickness, blood pressure and kinin-components in diabetic Wistar-Kyoto (WKY) rats. The 2nd Kuwait International Pharmaceutical Conference (KIPC), Kuwait, March 1 to March 3, 2009. Proceeding abstract No. 35. Poster. 57. Sharma, J. N. (2009). Role of bradykinin system in hypertension: prospects for future drug therapy. 4th Asian Association of Schools of Pharmacy and 9th Malaysian Pharmaceutical Society Conference, Penang, Malaysia. June 10 to June 13, 2009. Abstract No. page 58. Sharma, J. N. (2010) : Bradykinin system and rheumatoid arthritis: An overview. 24th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Shah Alam, Kuala Lumpur, Malaysia, June 2-3, 2010. Abstract Page No. 35. 38
  • 39. Curriculum Vitae of Jagdish N. Sharma 59. Sharma, J. N. (2011). Effect of indomethacin and prednisolone on tissue kallikrein activity in arthritic rats. The 3rd Kuwait International Pharmaceutical Conference (KIPC 2011), Kuwait, 14-16 February 2011. Proceeding abstract No. 63, page 97. Poster. 60. Sharma, J. N. (2011). Kallikrein-kinin pathway in cardiovascular and renal system: possibility for new drug development. 25th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Serdang, Selangore, Malaysia, May 25- 26, 2011. Abstract Page No. 14. Plenary Lecture 4. 61. Sharma, J. N. (2012). Bradykinin system: Role in hypertension and diabetes. 26th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Penang, Malaysia, May 18-20, 2012. Abstract Page No. 39. Plenary Lecture 6. 62. Sharma, J. N. (2013). : Kallikrein-kinin pathways in cardio-renal system: prospect of new drug development. 27th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Kuantan, Malaysia, September 6 - 8, 2013. Abstract Page 39-40. Plenary Lecture 3. 63. Sharma, J. N.; Al-Shoumer, K. A. S., Matar, K. M. and Madathil, N. V. (2013). Abnormal regulation of bradykinin-foring components in Kuwaiti patients with type 2 diabetes. The 5th International Conference on Fixed Combination in the Treatment of Hypertension, Dyslipidemia and Diabetes Mellitus, Bangkok, Thailand, November 21-24, 2013. Oral presentation. 64. Sharma, J. N.; Al-Shoumer, K. A. S., Matar, K. M. and Madathil, N. V. (2014). Abnormal pattern of bradykinin forming components and nitric oxide in Kuwaiti patients with type 2 diabetes, 19th HSC Poster Conference, Kuwait University, Kuwait. May 21-24, 2014. Poster presentation no. 184. 39
  • 40. Curriculum Vitae of Jagdish N. Sharma 65. Sharma, J. N. , Al-Shoumer, K. A. S., Matar, Madathil, N. V. and Al-Moalem, A.M.K. ( 2015). 'Influence of oral hypoglycemic agent on kininase II and nitric oxide activities in Kuwaiti patients with type 2 diabetes,' 20th HSC Poster Conference, Kuwait University, Kuwait. May 5-7 , 2014. Poster presentation no. 180. ADVISOR AND EVALUATOR OF NATINAL AND INTERNATIONAL RESEARCH GRANTS INTERNATIONAL: 40
  • 41. Curriculum Vitae of Jagdish N. Sharma 1. Telethon Combatti La Distrofia mauculare E Le Altre Malattie Genetiche, Rome, Italy. July 1999. 2. International Foundation for Science, Stockholm, Sweden. October 2001. 3. Raine Priming Grants, School of Medicine and Pharmacology, The University of Western Australia, Perth, WA. May 2010. NATIONAL: 1. Kuwait Foundation for the Advancement of Science, Kuwait. April, 2003. 2. Member of the Kuwait University Scientific Consultant Council, June, 2003. 3. Kuwait University Research Project, Kuwait, April, 2004. 4. Kuwait University Research Project, Kuwait, May, 2006. 5. Kuwait University Research Project, Kuwait, February, 2008. 41
  • 42. Curriculum Vitae of Jagdish N. Sharma 42