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1. Welcome
To
My presentation

2. Name: MD. Zahirul Islam
Roll:333
Batch:12th
Department of pharmacy
World University of Bangladesh

3. Presentation
of
Haematinics

4. Haematinics:
General term for those nutrients, including iron, folic
acid, and vitamin B 12, required for the formation and
development of blood cells in bone marrow (the
process of haematopoiesis), deficiency of which may
result in anaemia

5. Main Haematinics are:
1.Iron
2.Vit-B12
3. Folic acid

6. Iron As Haematinic Agent
 Hematopoiesis
 The production of circulating erythrocytes, leukocytes
and platelets from undifferentiated stem cells, is called
hematopoiesis.
 It requires:
 Iron –for Hb formation

7. Anemia:
 Decreased capacity of RBCs to carry oxygen to
tissues.
 Causes:
 Blood loss
 Impaired RBC functions, due to deficiency of

8. Iron deficiency occurs
 Iron deficiency occurs due to:
 Malnutrition
 Loss
 Congenital atransferrinemia (inability to release iron
from transferrin)

9. Iron storage
 Iron is the integral component of haeme. In our body:
 66-67% of iron is present in hemoglobin.
 3% occurs in myoglobin
 1% in enzymes -cytochrome, catalase, peroxidase
 25% is stored in form of ferritin and hemosiderin

10. Source of Iron
 Heme iron (present in meat)
 Inorganic iron
 Free inorganic iron is very toxic, thus there are
regulatory mechanisms for:
 a. Absorption
 b. Transport
 c. Storage of iron

11. Factors facilitating Iron Absorption
 Acid
 Acid enhances dissolution and reduction of ferric iron.
 Reducing Substances
 Ascorbic acid reduces ferric iron and forms absorbable
complexes
 Meat
 Meat also facilitates iron absorption by increasing HCl
secretion
 Pregnancy/ Menstruation
 Due to increased iron requirement

12. Vitamin B12
A vitamin important for the normal formation of red
blood cells and the health of the nerve tissues.
Undetected and untreated vitamin B12 deficiency can
lead to anemia and permanent nerve and brain
damage.

13. Causes of vit B12 deficiency
1.Decrease intake in diet
2. Increase demand during growing peroid pregnancy
3. Fish tape worm infestation

14. Vit B12 deficiency desease
1.Megaloblastic anemia
2. Crohn's disease
3.celiac disease

15. Folic acid
A yellow crystalline water-
soluble vitamin essential for cell growth and reproduct
ion. It functions as a coenzyme with
vitamins B12 in the metabolism and use of proteins an
d in the formation of nucleic acids and heme for
hemoglobin

16. Indication of folic acid
1.To treat megaloblastic anemia due to folate deficiency
2. Liver desease
3.Chronic disease
4. Renal dialysis
5. pregnancy

17. Thanks
to
All