Anginal pain in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) can present in several ways, including prolonged chest pain at rest lasting over 20 minutes, new onset chest pain classified as Canadian Cardiovascular Society class II or III, recently destabilized previously stable angina with class III characteristics, or chest pain following a myocardial infarction. The document provides recommendations on diagnosis, treatment strategies, timing of invasive procedures, and long-term management of patients presenting with NSTE-ACS.