A tour of a Radiopharmaceutical facility and a Nuclear Medicine department with ComecerGroup equipment.

1. Radiopharmaceutical
facility and Nuclear
Medicine department
A tour with Comecer

3. Cyclotron Bunker

4. PMC
Motorised doors for cyclotron bunkers
CYCLOTORONBUNKER
• Designed for non self-shielded cyclotrons
• Sliding movement
• Operated by wheel system connected to the electric gear motor

5. Control Room

6. SMARTGUARD
Environmental monitoring system
CONTROLROOM
• Real time and continuous control of the alarm level and measuring data
• Modular and flexible system
• Production, Area, Air, Neutron and Cleanroom monitoring

7. IBC Software
Workflow & management systems
CONTROLROOM
• IBC GMP Radiopharmacy for cyclotron facility, central pharmacy and academic hostpital
• IBC Nuclear Medicine for nuclear medicine departments of hospitals and clinics
• IBC Clinic for nuclear medicine departments and imaging centers

8. Hot Labs

9. BBS
Shielded cells for synthesis modules
HOTLABS
• Designed to host specific automatic synthesis modules
• Modular design and flexible configuration
• Available in Pb 75 or 100 mm shielding

10. TADDEO
Synthesis module
HOTLABS
• Automated module for synthesis of therapeutic radiopharmaceuticals
• Module contamination avoided by using disposable cassettes

11. ALCEO
Solid Target Processing System
HOTLABS
• Halogen System for 123I and 124I
• Metal System for 64Cu and 89Zr
• Modular design

12. TALIA
Class A laminar flow hot cells
HOTLABS
• Filling, calibrating and fractioning operations on vials or syringes
• Class A isolators equipped with laminar flow on the entire main chamber
• Designed to house automatic modules or fractioning systems in sterile conditions

13. CLIO
Volumetric Dispensing System
HOTLABS
• Formulation and automatic fractionation of radiopharmaceuticals (PET, SPECT and radio-treatments)
• Dispensing in open vials, closed vials (transseptal) or syringes with a pierceable connector
• Special aerodynamic profile that allows laminar flow to have total and effective coverage of dispensing area

14. FEBO
Syringes dispensing system
HOTLABS
• Designed for safe and accurate fractionation of radiopharmaceuticals in syringes
• Concentration calculation via volumetric sampling and activity measurement with integrated dose calibrator
• Compact size allows installation in cells with small working areas

15. ARGO
Vials dispensing system
HOTLABS
• Complies with the cGMP guidelines for filling open vials
• Dispenses radiotracers used in PET and SPECT diagnosis and therapeutic radiopharmaceuticals
• Controlled volume dispensing by means of an integrated pumping syringe in the disposable kit

16. MIP
Shielded cells for synthesis modules and research activities
HOTLABS
• Hosts automatic modules or research equipment of radioisotopes and radiopharmaceuticals
• Available in two sizes: 1100 mm and 1390 mm (work chamber width)
• Set-up for tele-manipulators and autoclave

17. THEODORICO
Automatic Dispensing System for Radiopharmaceuticals
HOTLABS
• Robotized automatic shielded dispensing system for radiopharmaceuticals in open or closed vials
• Aseptic operations or final sterilisation (with autoclave)
• Compliance with GMP requirements

18. ALTHEA PC
Automatic Dispensing System for Syringes
HOTLABS
• Automatic system for filling and calibration of syringes with radiopharmaceuticals
• Integrated Double dose calibrator
• Laminar air flow work area (Class A according to EEC-cGMP) for absolute product safety

19. Quality Control

20. Shipping Containers
Shielded container for vial transport
QUALITYCONTROL
• Lead shielded containers for vials transport
• Tungsten shielded containers for vials transport
• Equipped with a built-in handle for easy transport

21. Hoods
For manipulation at medium activity
QUALITYCONTROL
• Workstation for the breakdown of the airborne radioisotopes
• Designed in accordance with the current Radioprotection standards
• Absolute filter and active charcoal filter fitted with barrier bag housing

22. Work benches
Stainless steel
QUALITYCONTROL
• Ideal for Radiochemistry and Nuclear Medicine laboratories
• Worktop with raised border for holding liquids and no sharp edges to allow perfect residual removal
• AISI 304 stainless steel with Scotch-BriteTM finishing

23. VDC-606
Touch-screen Dose Calibrator
QUALITYCONTROL
• 10” touch screen with brilliant colours
• Accurate and fast measurements
• Easy to use

24. VCS
System for radio-TLC scanning and gamma spectrometry
QUALITYCONTROL
• Hardware and software package for testing radiochemical purity and for basic gamma spectrometry
• Available in two configurations, for low energy or high energy isotopes analysis
• IBC database connection

25. VLB Series
Hand-foot-clothing monitor
QUALITYCONTROL
• Detection technology based on failure-safe plastic scintillation detectors, developed specifically to
measure the beta and gamma emitting isotopes that are used in Nuclear Medicine departments
• Robust stainless steel surface

26. Injection Rooms

27. LETHO
Automatic Compact Injector
INJECTIONROOMS
• Gravity infusion or automatically controlled by a peristaltic pump
• Small dimensions and weight for simple handling and moving on the ward
• Compatible with different types of radio pharmaceuticals currently in clinical and pre-clinical use

28. IRIS
Automated Multidose Injection System
INJECTIONROOMS
• Performs calibrated injections to patients, starting from a multi-dose solution of radiopharmaceutical
• Can be connected via Wi-Fi to the hospital network
• Extremely easy to use thanks to the ergonomic positioning of the components

29. Technical Rooms

30. ACS
Air compressing station
TECHNICALROOMS
• Collects potentially radioactive air from inside hot cells during radiopharmaceutical production or after a
malfunction of the synthesis modules, starting automatically whenever the radioactivity level is too high
• Up to 16 chambers connected to the same system and up to 5 chambers in production simultaneously

32. 1MP
ONE MANUFACTURER PRACTICES
• Only one referent
• Highly experienced and qualified staff
• Design, Build, Upgrade and Certify GMP Laboratory

33. 1MP
ONE MANUFACTURER PRACTICES
• Only one referent
• Highly experienced and qualified staff
• Design, Build, Upgrade and Certify GMP Laboratory

34. Czech Republic
Netherlands
India
ChinaHeadquarter
USA
An International Group
“SAFETY FIRST” is our philosophy
• More than 40 years of experience in nuclear medicine and isolation technology
• Over 1000 installations worldwide
• 320 employees and growing

35. WHY CHOOSE COMECER?

36. Click on the logo to visit our website for more information