Urgent: healthcare startups can apply!

1. NOVARTIS START-UP
COMPETITION
AND EXHIBITION VIVA
TECHNOLOGY
PARIS / JUNE 30 – JULY 2

2. NOVARTIS INNOVATION
Novartis is a global healthcare company based in Switzerland with roots dating back
more than 150 years. We provide healthcare solutions that address the evolving
needs of patients and societies worldwide. Novartis products are available in more
than 180 countries and they reached nearly 1 billion people globally in 2015.
We develop innovative medicines to help people live better. Our mission is to discover
new ways to improve and extend people’s lives.
Rapid aging of the population, greater access to healthcare in emerging markets and
advances in science create opportunities to enhance the lives of patients through
innovation.
We focus on improving health outcomes for patients by leveraging medical
science, and advancing the creative use of new digital technology.
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3. WE ARE SELECTING
50 START-UPS FOR
3 DAYS OF
EXHIBITION AND
CO-WORKING.
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4. WHERE/WHEN
• JUNE 30 – JULY 2 in PARIS, the “EUROPEAN CES”
• 30-50k ATTENDEES and 5,000 STARTUPS
• 20 THEMED LABS (Healthtech, Fintech, Edutech, etc.)
• This large event has two main objectives:
– explore DIGITAL TRANSFORMATION
– reinforce LINKS between START-UPS, MULTI-NATIONAL
CORPORATIONS & INVESTORS
Our Goals:
• ENGAGE with start-ups to solve innovation CHALLENGES
• Evaluate and select relevant START-UPS for potential partnership
MORE INFO: http://www.vivatechnologyparis.com
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5. INNOVATION LAB
Novartis is the exclusive sponsor of a 500m2 LAB, where 50 START-
UPS will be pre-selected to PITCH and participate in CO-WORKING
and MEETINGS with Novartis executives.
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6. CHALLENGES
WE INVITE START-UPS TO HELP US SOLVE THESE CHALLENGES
1. NEUROSCIENCE: Digital solution sensitive enough to detect early
changes in cognitive function and reliably measure decline/progress
over time
2. RESPIRATORY: Digital solution to improve the life of asthma patients
3. RETINA: Affordable, digital, home eye monitoring tool that permits
patients to self-monitor and transmit results to doctors, thus avoiding
unnecessary and expensive clinic visits
4. MOVEMENT: Any solution that can measure movement, activity,
physical ability & capacity more accurately than what is available today
5. PATIENTS: Any solution that can help patients manage a disease,
monitor symptoms, optimize a treatment, get real time feedback and
disease history visualization
6. HEART FAILURE: Digital biomarkers and other diagnostic solutions to
identify at risk patients, diagnosed and/or undertreated
APPLY HERE6

7. WHY PARTICIPATE?
• PERSONAL EXHIBITION SPACE in the Novartis Health Tech Lab
• 2 ADMISSIONS per start up
• 3 days of CO-WORKING and NETWORKING
• PERSONALIZED MENTORING & coaching by Novartis executives and/or guest
experts
• Gain VALUABLE FEEDBACK on your ideas
• Explore COLLABORATION and discuss potential projects
• EXPOSURE at a premium event happening on a global stage
• Have fun and MAKE VALUABLE CONNECTIONS to help propel
your start-up forward
• Potential meeting with Novartis Investment team
• Potential invitation to a follow-up meeting at Novartis HQ in Basel Switzerland
Please be in touch with the.dal@novartis.com if you have a start-up that would be
interested in applying.
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8. 8
THE CHALLENGES

9. THE COGNITIVE CHALLENGE
Preserve Brain Health
Opportunity
Early detection of cognitive changes in people living with neurological conditions
can enable early/accelerated intervention; ultimately positively impact their and
their caregivers’ lives
Challenge
Digital solution that is sensitive enough to detect early changes in cognitive
function and reliably measures decline/progress overtime
Specific areas for consideration/
criteria for success
 Identify early indicators of cognitive impairment and/or decline
 (Passively) monitor changes in cognition over time
 Predict progression of cognitive decline and risk stratify patients
 Develop meaningful cognition-related outcomes (relevant to patient, caregivers,
clinicians, payor)
 Identify/detect differences in cognitive impairment related to different disease areas
(AD, MS, Parkinson's)
 Correlation/link between cognitive and functional decline
Prerequisites for the solution
 Language and culture neutral
 Independent of gross motor skills
 Not related to knowledge (educational level)
Other things to consider
 What is the baseline the solution is measuring against?
 Is one solution sensitive enough for both MS/AD?
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10. THE MOVEMENT CHALLENGE
Understanding Physical Activity & Capacity
Opportunity
Physical movement is often a great indicator of the evolution of a disease or the
efficacy of a treatment.
Challenge
Any solution that can measure movement, activity, physical ability & capacity,
more accurately than what is available today.
Specific areas for consideration/
criteria for success
 Measure movement, possibly to distinguish a variety of different movements
 Guarantee precision and accuracy of these measurements of movement
 Compare all actual movement measurement solutions /activity trackers (sensors,
phone, etc)
 Understand how the body progresses in the environment around it
 Imagine a home or a broader environment that understands a patient’s physical
activity (IoT, smart homes, etc.)
 Measure activity of people in wheelchairs, using walkers, crutches, prosthetics
 Easy to read/understand data visualization of the tracking
Prerequisites for the solution
 The solution has to be as straightforward as possible (no manual input, no need for
frequent battery charge, etc.)
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11. THE PATIENT CHALLENGE
Helping Patients Manage Their Condition
Opportunity
After being diagnosed with a disease or a chronic condition, patients are left with a
multitude of daily decisions to make to improve their condition, prevent deterioration
or episodes.
Challenge
Any solution that can help patients manage a disease, monitor symptoms,
optimize a treatment, get real time feedback and disease history visualization.
Specific areas for consideration/
criteria for success
 Monitor symptoms and episodes: record flare-ups / seizures / exacerbation,
 Monitor evolution / deterioration / progression of the disease
 Prepare relevant information for the physician appointment
 Give advice for day to day decisions
 Connect with other ecosystems (HealthKit, CareKit, Withings, etc.)
 Connect with other patients / physicians / nurses / family & friends, and help find
emotional support
 Solution could be IoT related (mirror, fridge, bed, etc.)
Prerequisites for the solution
 Solutions should help patients with chronic conditions like Asthma, Psoriasis,
Epilepsy, Trigeminal Neuralgia, Acne, Migraine, etc. in the long run
 The solution has to be very easy to use with as little manual input as possible
 Continuous and passive monitoring is preferable
 Beautiful and engaging look&feel of the solution
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12. THE RESPIRATORY CHALLENGE
Improving Asthma Treatment
Opportunity
Asthma patients have to manage their disease on a day-to-day basis. The physician
does not have sufficient information at hand and too little time to fully assess the
patient, or guide him, while the patient has too little information about his own
condition to effectively participate in the discussion or manage his condition by
himself.
Challenge Digital solution that will improve the life of patients with Asthma.
Specific areas for consideration/
criteria for success
 Optimize the limited time with the patient at ‘point of care’, for example by allowing
the patient to provide information to the physician ahead of time and facilitate the,
evaluation of the disease
 Decision making tools (about treatments and lifestyle choices) to both the patient
and the physician
 Improve patients’ experience and treatment outcomes
 Understand the climatic conditions and pollen load as potential triggers, to predict
and avoid exacerbations
 Take the right dose at the right time to optimize comfort, sleep, QoL
 Help patients better navigate through the healthcare system
 Allow the payor to measure treatment outcomes value for their insured population
Prerequisites for the solution
 Solutions can be based on the signals collected from the eBreezhaler (tech
specifications on demand).
 Language and culture neutral
 Leverages existing technology (e.g., mobile devices) and non-proprietary systems.
 Not related to knowledge (educational level)
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13. THE RETINA CHALLENGE
Reduced Patient Burden, Better Outcomes
Opportunity
Patients with retina diseases need to have different eye examinations in the clinic
on regular schedule to monitor their disease activity and decide if treatment is
needed. These visits are a burden on patients and providers and drive
unnecessary expense.
Challenge
Affordable, digital, at home monitoring tool that permits patients to self-
monitor and transmit results to doctors, thus avoiding unnecessary and
expensive clinic visits.
Specific areas for consideration/
criteria for success
 Ability to safely view and record high resolution images of the retina – equivalent to
images generated by OCT and fundus cameras
 Ability to monitor evolution / deterioration / progression of the disease
 Transmit information to physician and / or prepare relevant information for the
physician appointment
 Remind patients of scheduled time for self—evaluation / monitoring
 Record and store images / information generated by the device / solution
 Home-based, low patient burden – without need for frequent recharging
Prerequisites for the solution
 Affordable – less than $100
 Simple, safe, and easy to use, especially for older, less tech-savvy patients
 Not related to knowledge (educational level)
Other things to consider
 Can the device/solution be used both by the patient and by a novice caregiver?
 Is a separate solution required for pediatric patients, for geriatric patients?
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14. THE HEART CHALLENGE
Predicting Heart Failure
Opportunity
Heart failure is a gradual condition often mistaken for signs of aging. Early
prediction of heart failure could help more than 12 million patients live longer, more
normal lives and reduce significantly the extraordinary cost burden through
reduced rates and length of hospitalization.
Challenge
Digital biomarkers or similar early diagnostic solutions to identify as early as
possible patients either at risk for heart failure or diagnosed for heart failure
but undertreated.
Specific areas for consideration/
criteria for success
 Early diagnosis of heart failure – 1-2 years earlier than current standard of care
 Uses digital biomarker/big data-predictive algorithm to diagnose/predict heart
failure or patients potentially at risk of heart failure
 (Passively) monitors disease progression or symptoms progression and identify
likely undertreatment.
 Risk-stratification algorithm or other data-driven mechanism to identify high risk
patients
 Leverages user-supplied data or existing/available data (e.g. credit card data) to
support predictive, learning algorithms
Prerequisites for the solution
 Language and culture neutral
 Globally/universally applicable
 Not related to knowledge (educational level)
Other things to consider
 Is a single approach possible for undiagnosed patients as well as diagnosed but
likely undertreated patients?
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