13. Ca colon
unexplained anemia is the common
presentation
Altered bowel habits , obstruction ,
perfotation, bleeding
hard, nontender, fixed mass
14.
15. Aetiology
1. DIET -Red meat, saturated fat and cholesterol
2.Alcohol and smoking
3.Radiation
4. Post-cholecystectomy and ileal resection and
ureterocolostomy status
5.Genetic causes
Familial Adenomatous polyposis coli.
Gardner's syndrome and Turcot’s syndrome.
Peutz jeger’s syndrome and Juvenile polyposis
syndrome.
HNPCC , Lynch syndrome1, Lynch syndrome 2
Aspirin and other NSAIDs, calcium are protective
against large bowel cancers
17. Retroperitoneal sarcoma
• liposarcoma is commonest sarcoma
• present as asymptomatic mass , obstruction
of bowel , ureter , vessels
• CECT , MRI
• wide local excision , multivisceral resection
• chemoradiation
18.
19. Adrenal tumours
Adrenal cortical tumours
o Mostly benign (1%malignant)
o functioning or non-functioning tumours
o functioning tumours secrete sex hormones ,
mineralocorticoid , glucocorticoid
o non-functioning tumours commonly present as
incidentalomas
o Diagnosis by hormone assay, USG, CT
o adrenalectomy for benign adenomas
o Radical adrenalectomy+chemotherapy
20. Adrenal medullary tumours
neuroblastoma
• Commonest childhood tumour.
• It is a tumour of adrenal medulla.
• An aggressive malignant tumour in childhood
usually below the age of 5 years.
• asymptomatic mass , liver secondaries , orbital
secondaries , dancing eye syndrome ,
opsomyoclonus
• USG, CT, MRI, MIBG scan , urinary VMA
• adrenalectomy , debulking , chemotherapy
21. PHAEOCHROMOCYTOMA
• adrenal medullary tumour
• it is a norepinephrine secreting tumour
• benign or malignant
• headache , persistant or paroxysmal
hypertension , sympathetic overactivity
• may be associated with MEN-2 syndrome
• serum/ urinary
metanephrines/normetanephrines USG, CT, MRI,
MIBG scan
• surgical resection
22. Renal masses
• Cystic diseases of kidney
• hydronephrosis
• inflammatory mass
• Perinephric abscess
• renal tumours
31. Wilms tumour
• common in first 4 years of life.
• arises from embryonic tissue containing epithelial
and connective tissue elements.
• bilateral in 5% cases.
• mass , fever, pain, hypertension , hematuria ,
congenital anomalies
• USG, CT, MRI,IVU
• nephroureterectomy + chemotherapy +
radiotherapy
32. Renal cell carcinoma
• Hypernephroma, Grawitz tumour
• It is an adenocarcinoma arising from renal
tubular cells
• More common in males; more common in 5th-
6th decade of life.