Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Upcoming SlideShare
Jenner And Smallpox
Next
Download to read offline and view in fullscreen.

Share

edward jenner

Download to read offline

edward jenner

Related Books

Free with a 30 day trial from Scribd

See all

Related Audiobooks

Free with a 30 day trial from Scribd

See all

edward jenner

  1. 1. Edward Jenner Gopisankar.M.G. 2008 MBBS
  2. 2. Edward Jenner(1749-1823)  Pioneer of small pox vaccine  Father of immunology
  3. 3. life of Jenner….  Born on 17th May 1749(Berkeley)  From the age of 14yrs ,trained as apprentice to Daniel Ludlow, a surgeon  In 1770-worked under surgeon John Hunter at St.George’s hospital.  Returned to Berkeley in 1773,practised as GP & surgeon.  Edward Jenner died of stroke at the age of 73, on 26 January 1823
  4. 4. Small pox  Disease goes through stages of macules ,papules, vesicles,pustules over the skin.  Severe forms- hemorrhagic
  5. 5.  Greatly feared disease for thousands of years  Caused by Variola virus  1/3rd of the patients died  Survivors –badly disfigured  10 yrs before eradication ,the disease was present in 44 countries, with a global incidence of around 10 million cases annually !!!
  6. 6. Jenner Vs Pox  Jenner’s initial theory- The initial source of infection was a disease of horses, called "the grease", and that this was transferred to cows by farm workers, transformed, and then manifested as cowpox.  He noted-Milkmaids don't generally get small pox  He theorized it-pus in the blisters which milkmaids received from cowpox (a disease similar to smallpox, but much less virulent) protected the milkmaids from smallpox.
  7. 7.  On 14 May 1796,  Inoculated James Phipps, a young boy of 8 years (the son of Jenner's gardener), with material from the cowpox blisters of the hand of Sarah Nelmes, a milkmaid who had caught cowpox from a cow called Blossom  produced a fever and some uneasiness but no great illness  Injected Phipps with variolous material –No disease followed  Again challenged with variolous material-but no sign of infection
  8. 8. Why Jenner was successful??  Not only inoculated cowpox ,but also proved that they are immune to small pox  Demonstrated that the protective cowpox could be effectively inoculated from person to person, not just directly from cattle.  He tested his theory on a series of 23 subjects. This aspect of his research method increased the validity of his evidence.
  9. 9.  He continued his research and reported it to the Royal Society, who did not publish the initial report.  After improvement and further work, he published a report of twenty-three cases  In 1803 in London he became involved with the Jennerian Institution, a society concerned with promoting vaccination to eradicate smallpox.
  10. 10. Post- Jenner era  17 yrs after his death(1840), British government banned variolation ( the use of smallpox itself)  and provided vaccination (using cowpox )free of charge.  In 1976,Global eradication programme of Smallpox –initiated by WHO.  After 10 years-disease was wiped out ,
  11. 11.  .  Last stock is in – USA and Russia  They were to be destroyed by June 30 , 1999.  But fears of the possible use of small pox in bioterrorism led to an indefinite extension of the deadline.  Whole world was certified “small pox free area” in October 1979.  Formally declared by WHO in 8th May 1980
  12. 12. Remembering the great man….. -Jenner's house is now a small museum housing among other things the horns of the cow, Blossom (Berkeley). -Near the small Gloucestershire village of Uley, Downham Hill is locally known as 'Smallpox Hill', with a possible connection to Jenner's local work with the disease.
  13. 13.  A statue was erected in Trafalgar Square, later moved to Kensington Gardens. 
  • RESHMAS64

    Sep. 8, 2021
  • JmLkh1

    Jun. 8, 2021
  • AbhishekKumar6149

    Feb. 16, 2021
  • MohamedYahya55

    Oct. 15, 2020
  • AbhishekGandha

    Aug. 26, 2020
  • KhushiKattimaniKatti

    Aug. 23, 2020
  • AnshiKm1

    Jul. 1, 2020
  • LahariYangala

    Jan. 20, 2019
  • Ishwaryanarayan3798

    Nov. 4, 2018
  • AthulVakayad

    Aug. 3, 2018
  • AbdulFarooqui5

    Jun. 5, 2018
  • VipinKRavi

    Aug. 11, 2017

edward jenner

Views

Total views

12,404

On Slideshare

0

From embeds

0

Number of embeds

8

Actions

Downloads

322

Shares

0

Comments

0

Likes

12

×