Each year 1.7 million Americans are diagnosed with sepsis, resulting in 270,000 deaths, according to the Centers for Disease Control and Prevention. That’s one death every two minutes, making sepsis the leading cause of death in U.S. hospitals. The financial toll is also high, with the average cost per sepsis stay over $18,000. Sepsis is the number one cause of both initial hospitalizations and readmissions. Nearly all sepsis deaths are preventable. Community outreach, focused attention on the emergency department, and effective technology and processes to monitor patients already admitted can reduce sepsis mortality. Making a goal of “zero sepsis deaths” a reality is a personal and professional passion of Armando Nahum, a patient activist and co-founder and President of the Safe Care Campaign, and Kathleen Merkley, DNP, ANP, FNP, Senior Vice President of Professional Services at Health Catalyst. Nahum and Merkley share stories and practical steps to drastically reduce the sepsis toll. Michael L. Millenson, Senior Advisor to Health Catalyst, patient safety expert, and long-time advocate of safer, higher-quality, more patient-centered care, facilitates the dialogue. What You’ll Learn - How to implement community outreach to facilitate timely sepsis recognition and seeking of care. - How to organize emergency department processes for prompt sepsis recognition and treatment. - How to ensure prompt sepsis recognition and treatment in the inpatient environment. - How to avoid sepsis readmissions.

1. © 2021 Health Catalyst
© 2021 Health Catalyst
May 12, 2021
Zero Sepsis Deaths: A Dialogue of Passion and
Practical Wisdom on Sepsis Prevention

2. Agenda
Kathleen Merkley, DNP, ANP, FNP
Senior Vice President, Clinical Improvement Services, Health Catalyst
Armando Nahum
Director, Center for Engaging Patients as Partners, MedStar Institute
for Quality and Safety

3. Poll Question #1
How would you describe your affiliation?
• Hospital or health system administrative position
• Clinician
• Patient activist
• Consultant/Researcher
• Other

4. My Experience with Sepsis as a Young Nurse

5. Vendetta Against Sepsis

6. Joshua Nahum

7. Poll Question #2
Either in a professional capacity or as an individual, have you ever personally witnessed,
or heard from a first-hand account, a sepsis death that seemed to you was preventable?
• Yes
• No
• Unsure

9. Think Sepsis, Say Sepsis

10. Combating Sepsis with Analytics, Best Practice and
Adoption

11. Real-World Clinical and Financial ROI
• 45.3% relative reduction in severe sepsis and septic shock mortality rate and
14.4% relative reduction in length of stay for those who became septic as
inpatients
• 36.4% relative reduction in sepsis mortality rate, sustaining previous
improvement for more than three years
• 1.6-day reduction in ICU length of stay and 1.1-day reduction for patients with ED
sepsis POA
• 50% relative reduction in mortality for patients ED severe sepsis POA and 14%
relative reduction for ED septic shock POA
• $5.5 million in savings by reducing average variable cost of care for ED sepsis POA
and inpatient cohort with sepsis, while also capturing patients for downstream
care delivery

12. Successes: Early Warnings, Saving Lives
• Early warning alerts refined with machine learning
• Improved triage practices
• Improved times with 3-hour bundle metrics
• Enhanced compliance – repeat lactate/tissue perfusion compliance
• CDC sepsis surveillance cohort
• Readmission prediction – transitions of care
• Identification of sepsis patients admitted within 24 hours
• Automated physician/nurse compliance notification
• Decreased CMS abstraction time

13. Zero Sepsis Deaths: A Dialogue of Passion and Practical Wisdom
on Sepsis Prevention

14. The Healthcare Analytics Summit 2021 - Virtual
Visit hasummit.com to register and learn more
• Industry-Leading Featured Speakers
• 21 Educational Breakout Sessions
• CME Accreditation for Clinicians
• Analytics and AI Showcases, Networking, and More
• Virtual Platform optimized for a live experience
Sept. 21 – 23, 2021 (half-day sessions)
o Steve Kerr
o Rana el Kaliouby, PhD
o Vin Gupta, MD, MPA, MSc
o Chris Chen, MD
o Amy Compton-Phillips, MD
o Brent C. James, MD, Mstat
o Sadiqa Mahmood, DDS, MPH
“The virtual experience was beyond any other that I've
attended. You all did a wonderful job of creating an "in-
person" feel and I appreciate that as a learner. The virtual
platform was very intuitive and fun.”

15. Poll Question #3
Would you like to be entered to win one of three complimentary passes to HAS 21
Virtual?
• Yes
• No

16. Poll Question #4
Would you like to learn more Health Catalyst products and services?
• Yes
• No

17. Q&A

18. Thank you!
kathleen.merkley@healthcatalyst.com
armando.nahum@medstar.net
michael@healthqualityadvisors.com