SlideShare une entreprise Scribd logo
1  sur  63
,  COPD: CPT 1 UTECH  Dr E. Watson PharmD.
Learning Objectives :  upon completion of this lecture, the student should be able to   ,[object Object],[object Object],[object Object],[object Object],[object Object]
Learning Objectives Cont’d. ,[object Object],[object Object],[object Object],[object Object]
Key Points ,[object Object],[object Object],[object Object]
Key Points cont’d. ,[object Object],[object Object]
Key Points cont’d. ,[object Object],[object Object],[object Object]
Definition: National Heart, Lung and Blood institute (NHLBI) and WHO ,[object Object],[object Object],[object Object]
Definition: GOLD ,[object Object],[object Object]
Chronic Bronchitis ,[object Object],[object Object],[object Object]
Emphysema ,[object Object]
Emphysema ,[object Object],[object Object]
Chronic Asthma ,[object Object],[object Object],[object Object]
Risk factors: Major ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Risk factors: Minor ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathophysiology; Chronic Bronchitis ,[object Object],[object Object]
Pathophysiology; Chronic Bronchitis ,[object Object],[object Object]
Pathophysiology; Chronic Bronchitis ,[object Object],[object Object]
Pathophysiology; Emphysema ,[object Object],[object Object],[object Object]
Pathophysiology; Emphysema ,[object Object],[object Object]
Clinical assessment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Laboratory Test. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Classification of COPD by severity. Stage Lung Function Stage 1:  Mild COPD  FEV1/FVC < 70% FEV1  >  80% predicated  Stage 2:  Moderate COPD   FEV1/FVC < 50 - 70% FEV1 < 80% predicated  Stage 3  Severe COPD  FEV1/FVC < 30 - 70% FEV1 < 50% of pred. Stage 4:  Very Severe COPD   FEV1/FVC < 70% FEV1  < 3 0% predicated or FEV1 is < 50% predicated and respiratory failure
Differentiating Characteristics Chronic Bronchitis Emphysema Overweight (blue bloater)   Thin (pink puffer)   Mild Dyspnea   Severe Dyspnea   Copious Sputum Scanty Sputum   Frequent Infections Less frequent Infections   Hypoxemia Hypoxemia uncommon   Barrel chest Flattened Diaphragm   Cor pulmonale Diffusion  capacity decreased
Factors Determining Severity of Chronic COPD.  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Components of COPD Management. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Goals of Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object]
Goals of Therapy ,[object Object],[object Object],[object Object]
Non-Pharmacological Management. (NPT) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Discontinue Smoking ,[object Object],[object Object],[object Object],[object Object]
Chest Physiology ,[object Object],[object Object],[object Object]
Breathing Exercises ,[object Object],[object Object],[object Object]
Rehabilitation ,[object Object],[object Object],[object Object],[object Object]
Preventative Measures ,[object Object],[object Object],[object Object]
Pharmacological Management of COPD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Oxygen Therapy ,[object Object],[object Object]
Oxygen Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object]
Anticholinergics  (e.g. Ipratropium Bromide, Atropine, Glycopyrrolate, Tiotropium bromide ,[object Object],[object Object],[object Object],[object Object]
MOA ,[object Object],[object Object],[object Object]
MOA ,[object Object],[object Object],[object Object],[object Object]
Dosing ,[object Object],[object Object],[object Object],[object Object],[object Object]
Short acting Beta Agonist (salbutamol, albuterol  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MOA / DOSE ,[object Object],[object Object],[object Object]
Long Acting Beta  Agonist;  (salmeterol, formeterol)   ,[object Object],[object Object],[object Object],[object Object]
Combination Therapy ( Ipatropium/Albuterol) ,[object Object],[object Object],[object Object],[object Object]
Theophylline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Dosing ,[object Object],[object Object],[object Object],[object Object],[object Object]
Oral Steroids ,[object Object],[object Object],[object Object],[object Object]
Inhaled steroids ,[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object]
Antibiotics ,[object Object],[object Object],[object Object],[object Object]
Summary of Therapy by Stage.
Measure of Drug Effects ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Measure of Drug Effects ,[object Object],[object Object],[object Object],[object Object]
Monitoring for Efficacy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Monitoring for Toxicity ,[object Object],[object Object],[object Object]
Role of the Pharmacist in the management of COPD. ,[object Object],[object Object],[object Object]
Role of the Pharmacist in the management of COPD. ,[object Object],[object Object]
Complications of COPD ,[object Object],[object Object],[object Object],[object Object]
Take Home Points/ Summary. ,[object Object],[object Object],[object Object],[object Object]
Take Home Points/ Summary. ,[object Object],[object Object],[object Object],[object Object]
Take Home Points/ Summary. ,[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The End Questions

Contenu connexe

Tendances

Acute exacerbation of COPD
Acute exacerbation of COPDAcute exacerbation of COPD
Acute exacerbation of COPDThomas Kurian
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseimangalal
 
Pharmacological Management of COPD
Pharmacological Management of COPD  Pharmacological Management of COPD
Pharmacological Management of COPD Ashraf ElAdawy
 
COPD: Management of Acute Exacerbation
COPD: Management of Acute ExacerbationCOPD: Management of Acute Exacerbation
COPD: Management of Acute Exacerbationmustaqadnan1
 
Chronic Obstructive Pulmonary Disease - COPD
Chronic Obstructive Pulmonary Disease - COPDChronic Obstructive Pulmonary Disease - COPD
Chronic Obstructive Pulmonary Disease - COPDEneutron
 
bronchitis (pathology and treatment)by srota dawn
bronchitis (pathology and treatment)by srota  dawnbronchitis (pathology and treatment)by srota  dawn
bronchitis (pathology and treatment)by srota dawnSrota Dawn
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease  Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease YMC Medicine
 
Management of asthma
Management of asthmaManagement of asthma
Management of asthmaKhairul Jessy
 
Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Nandinii Ramasenderan
 
Lecture 5 asthma and copd
Lecture 5  asthma and copdLecture 5  asthma and copd
Lecture 5 asthma and copdMohanad Mohanad
 

Tendances (20)

Acute exacerbation of COPD
Acute exacerbation of COPDAcute exacerbation of COPD
Acute exacerbation of COPD
 
Asthma
AsthmaAsthma
Asthma
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary disease
 
COPD
COPD COPD
COPD
 
COPD
COPD COPD
COPD
 
Copd
CopdCopd
Copd
 
Pneumonia
PneumoniaPneumonia
Pneumonia
 
Pharmacological Management of COPD
Pharmacological Management of COPD  Pharmacological Management of COPD
Pharmacological Management of COPD
 
COPD: Management of Acute Exacerbation
COPD: Management of Acute ExacerbationCOPD: Management of Acute Exacerbation
COPD: Management of Acute Exacerbation
 
Chronic Obstructive Pulmonary Disease - COPD
Chronic Obstructive Pulmonary Disease - COPDChronic Obstructive Pulmonary Disease - COPD
Chronic Obstructive Pulmonary Disease - COPD
 
Asthma
Asthma Asthma
Asthma
 
Pneumonia
Pneumonia Pneumonia
Pneumonia
 
bronchitis (pathology and treatment)by srota dawn
bronchitis (pathology and treatment)by srota  dawnbronchitis (pathology and treatment)by srota  dawn
bronchitis (pathology and treatment)by srota dawn
 
Copd
CopdCopd
Copd
 
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease  Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
 
Management of asthma
Management of asthmaManagement of asthma
Management of asthma
 
Bronchial asthma management
Bronchial asthma managementBronchial asthma management
Bronchial asthma management
 
Copd 2012
Copd 2012Copd 2012
Copd 2012
 
Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)Chronic obstructive airway disease (coad)
Chronic obstructive airway disease (coad)
 
Lecture 5 asthma and copd
Lecture 5  asthma and copdLecture 5  asthma and copd
Lecture 5 asthma and copd
 

Similaire à Copd lecture notes

COPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)AyurvedaCOPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)AyurvedaRaghavendraPujari1
 
copdaslam-160531103105.pdf
copdaslam-160531103105.pdfcopdaslam-160531103105.pdf
copdaslam-160531103105.pdfAbdrahmanDOKMAK1
 
Chronic obstructive pulmonary disease by aminu arzet
Chronic obstructive pulmonary disease by aminu arzetChronic obstructive pulmonary disease by aminu arzet
Chronic obstructive pulmonary disease by aminu arzetAminuArzet
 
COPD
COPDCOPD
COPDUVAS
 
Chronic obstructive pulmonary diseases & Nursing care.
Chronic obstructive pulmonary diseases & Nursing care.Chronic obstructive pulmonary diseases & Nursing care.
Chronic obstructive pulmonary diseases & Nursing care.V4Veeru25
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseDrRavi Jain
 
Chronic obstructive pulmonary disease ppt
Chronic obstructive pulmonary disease   pptChronic obstructive pulmonary disease   ppt
Chronic obstructive pulmonary disease pptMeklelle university
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary diseasepradeepmk8
 
Advanced Practice Powerpoint
Advanced Practice Powerpoint Advanced Practice Powerpoint
Advanced Practice Powerpoint kaugustine66
 
Presentation adv practice 1
Presentation adv practice 1Presentation adv practice 1
Presentation adv practice 1kaugustine66
 

Similaire à Copd lecture notes (20)

Copd
CopdCopd
Copd
 
COPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)AyurvedaCOPD(Chronic Obstructive Pulmonary Disease)Ayurveda
COPD(Chronic Obstructive Pulmonary Disease)Ayurveda
 
copdaslam-160531103105.pdf
copdaslam-160531103105.pdfcopdaslam-160531103105.pdf
copdaslam-160531103105.pdf
 
COPD & asthma.ppt
COPD & asthma.pptCOPD & asthma.ppt
COPD & asthma.ppt
 
COPD.pptx
COPD.pptxCOPD.pptx
COPD.pptx
 
Chronic obstructive pulmonary disease by aminu arzet
Chronic obstructive pulmonary disease by aminu arzetChronic obstructive pulmonary disease by aminu arzet
Chronic obstructive pulmonary disease by aminu arzet
 
COPD
COPDCOPD
COPD
 
2 COPD.ppt
2  COPD.ppt2  COPD.ppt
2 COPD.ppt
 
Copd , septicshock
Copd , septicshockCopd , septicshock
Copd , septicshock
 
Chronic obstructive pulmonary diseases & Nursing care.
Chronic obstructive pulmonary diseases & Nursing care.Chronic obstructive pulmonary diseases & Nursing care.
Chronic obstructive pulmonary diseases & Nursing care.
 
copd.pptx
copd.pptxcopd.pptx
copd.pptx
 
Copd(留学生2009)
Copd(留学生2009)Copd(留学生2009)
Copd(留学生2009)
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary disease
 
Copd
CopdCopd
Copd
 
Chronic obstructive pulmonary disease ppt
Chronic obstructive pulmonary disease   pptChronic obstructive pulmonary disease   ppt
Chronic obstructive pulmonary disease ppt
 
Chronic obstructive pulmonary disease
Chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease
Chronic obstructive pulmonary disease
 
Mahu copd
Mahu copdMahu copd
Mahu copd
 
Advanced Practice Powerpoint
Advanced Practice Powerpoint Advanced Practice Powerpoint
Advanced Practice Powerpoint
 
Presentation adv practice 1
Presentation adv practice 1Presentation adv practice 1
Presentation adv practice 1
 
Pulmonology
PulmonologyPulmonology
Pulmonology
 

Plus de homebwoi

Glaucoma Treatment
Glaucoma TreatmentGlaucoma Treatment
Glaucoma Treatmenthomebwoi
 
THE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDF
THE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDFTHE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDF
THE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDFhomebwoi
 
Mastery - The Keys To Success And Long-Term Fulfillment - George Leonard
Mastery - The Keys To Success And Long-Term Fulfillment - George LeonardMastery - The Keys To Success And Long-Term Fulfillment - George Leonard
Mastery - The Keys To Success And Long-Term Fulfillment - George Leonardhomebwoi
 
Therapeutic systems lecture 5
Therapeutic systems lecture 5Therapeutic systems lecture 5
Therapeutic systems lecture 5homebwoi
 
Drug excretion lecture 10
Drug excretion  lecture 10Drug excretion  lecture 10
Drug excretion lecture 10homebwoi
 
Cpt htn march 2010
Cpt   htn march 2010Cpt   htn march 2010
Cpt htn march 2010homebwoi
 
Case presentation pud
Case presentation pudCase presentation pud
Case presentation pudhomebwoi
 
Biopharmaceutics lecture 2(2)
Biopharmaceutics lecture 2(2)Biopharmaceutics lecture 2(2)
Biopharmaceutics lecture 2(2)homebwoi
 
Biopharmaceutics lecture 2
Biopharmaceutics lecture 2Biopharmaceutics lecture 2
Biopharmaceutics lecture 2homebwoi
 
Biopharmaceutics lecture4(2)
Biopharmaceutics lecture4(2)Biopharmaceutics lecture4(2)
Biopharmaceutics lecture4(2)homebwoi
 
Biopharmaceutics lecture4
Biopharmaceutics lecture4Biopharmaceutics lecture4
Biopharmaceutics lecture4homebwoi
 
Biopharmaceutics lecture1(2)
Biopharmaceutics lecture1(2)Biopharmaceutics lecture1(2)
Biopharmaceutics lecture1(2)homebwoi
 
Biopharmaceutics lecture1
Biopharmaceutics lecture1Biopharmaceutics lecture1
Biopharmaceutics lecture1homebwoi
 
Bioavailability studies lecture7
Bioavailability studies lecture7Bioavailability studies lecture7
Bioavailability studies lecture7homebwoi
 
Bioavailability studies ii
Bioavailability studies iiBioavailability studies ii
Bioavailability studies iihomebwoi
 
Therapeutic systems lecture 5 b
Therapeutic systems lecture 5 bTherapeutic systems lecture 5 b
Therapeutic systems lecture 5 bhomebwoi
 

Plus de homebwoi (16)

Glaucoma Treatment
Glaucoma TreatmentGlaucoma Treatment
Glaucoma Treatment
 
THE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDF
THE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDFTHE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDF
THE POWER OF PERSUASION How We’re Bought and Sold - Robert Levine.PDF
 
Mastery - The Keys To Success And Long-Term Fulfillment - George Leonard
Mastery - The Keys To Success And Long-Term Fulfillment - George LeonardMastery - The Keys To Success And Long-Term Fulfillment - George Leonard
Mastery - The Keys To Success And Long-Term Fulfillment - George Leonard
 
Therapeutic systems lecture 5
Therapeutic systems lecture 5Therapeutic systems lecture 5
Therapeutic systems lecture 5
 
Drug excretion lecture 10
Drug excretion  lecture 10Drug excretion  lecture 10
Drug excretion lecture 10
 
Cpt htn march 2010
Cpt   htn march 2010Cpt   htn march 2010
Cpt htn march 2010
 
Case presentation pud
Case presentation pudCase presentation pud
Case presentation pud
 
Biopharmaceutics lecture 2(2)
Biopharmaceutics lecture 2(2)Biopharmaceutics lecture 2(2)
Biopharmaceutics lecture 2(2)
 
Biopharmaceutics lecture 2
Biopharmaceutics lecture 2Biopharmaceutics lecture 2
Biopharmaceutics lecture 2
 
Biopharmaceutics lecture4(2)
Biopharmaceutics lecture4(2)Biopharmaceutics lecture4(2)
Biopharmaceutics lecture4(2)
 
Biopharmaceutics lecture4
Biopharmaceutics lecture4Biopharmaceutics lecture4
Biopharmaceutics lecture4
 
Biopharmaceutics lecture1(2)
Biopharmaceutics lecture1(2)Biopharmaceutics lecture1(2)
Biopharmaceutics lecture1(2)
 
Biopharmaceutics lecture1
Biopharmaceutics lecture1Biopharmaceutics lecture1
Biopharmaceutics lecture1
 
Bioavailability studies lecture7
Bioavailability studies lecture7Bioavailability studies lecture7
Bioavailability studies lecture7
 
Bioavailability studies ii
Bioavailability studies iiBioavailability studies ii
Bioavailability studies ii
 
Therapeutic systems lecture 5 b
Therapeutic systems lecture 5 bTherapeutic systems lecture 5 b
Therapeutic systems lecture 5 b
 

Copd lecture notes

  • 1. , COPD: CPT 1 UTECH Dr E. Watson PharmD.
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22. Classification of COPD by severity. Stage Lung Function Stage 1: Mild COPD FEV1/FVC < 70% FEV1 > 80% predicated Stage 2: Moderate COPD FEV1/FVC < 50 - 70% FEV1 < 80% predicated Stage 3 Severe COPD FEV1/FVC < 30 - 70% FEV1 < 50% of pred. Stage 4: Very Severe COPD FEV1/FVC < 70% FEV1 < 3 0% predicated or FEV1 is < 50% predicated and respiratory failure
  • 23. Differentiating Characteristics Chronic Bronchitis Emphysema Overweight (blue bloater) Thin (pink puffer) Mild Dyspnea Severe Dyspnea Copious Sputum Scanty Sputum Frequent Infections Less frequent Infections Hypoxemia Hypoxemia uncommon Barrel chest Flattened Diaphragm Cor pulmonale Diffusion capacity decreased
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32.
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44.
  • 45.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51. Summary of Therapy by Stage.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 58.
  • 59.
  • 60.
  • 61.
  • 62.

Notes de l'éditeur

  1. Students to fill in toxicities.