2. What is Anxiety?
Anxiety is a normal response to danger.
Normal emotion/mood
Enhances performance
Useful in 3 ways: fight, flight, freeze
Closely coupled with somatic, autonomic
and psychological components
Abnormal, when out of proportion or
outlasts the threat
5. Definition Of Anxiety Disorders
Abnormal states in which the most
striking features are mental and
physical symptoms of anxiety,
occurring in the absence of organic
brain disease or another psychiatric
disorder.
7. Etiology Of Anxiety Disorders
stress Diasthesis model:
Appear to be caused by stressors acting
on a personality predisposed by a
combination of genetic factors and
environmental influences in childhood.
8. Stressful life events
Genetic causes
Psychoanalytical theories
Cognitive – behavioural theory
Neurobiological mechanisms
9. G.A.D.
Lifetime prevalence: 5 – 9 %
M : F ratio 2 : 1
Key features:
• Worry and apprehension
• Muscle tension
• Autonomic overactivity
• Psychological arousal
• Sleep disturbances
All the above are persistent and pervasive
Not dependent on any circumstances
11. Diagnosis
Presence of symptoms for most days
of the week for at least several weeks
at a time and usually for several
months
Presence of symptoms for at least 6
months duration
13. Prognosis
Longer the duration, poorer the prognosis
Frequent depressive episodes on follow – up
Co-morbidity: substance misuse, avoidance of
situations (social and agoraphobia); will have
poorer prognosis.
14. Treatment
Counselling – effective mainly in early
stages
Relaxation training – effective in less
severe disorders
CBT – 50% reduction in anxiety
symptoms, low drop-out rates
15. Medication – used to reduce anxiety
quickly and make patient amenable
to undergo CBT
• Benzodiazepines
• Beta blockers
• Anti-depressants
16. Phobic anxiety disorders
Anxiety symptoms only in particular
situations associated with avoidance of
those situations and having anticipatory
anxiety
3 syndromes:
• Specific phobia
• Social phobia
• Agoraphobia
18. Clinical features
Inappropriately anxious in the
presence of one or more objects or
situations
Whole range of symptoms can be
experienced
Anticipatory anxiety
Escape or avoidance from feared
situation
19. Types of specific phobia
Animals
Aspects of natural environment : Height
Blood, injections, injuries: different autonomic
response; tachycardia f/b vasovagal response
helped by tensing muscles
Situations: flying
Dental and medical situations: phobia of illness
Phobia of choking
20. Treatment
Medications:
Benzodiazepines (risk of dependance)
Only short course recommended
Behaviour therapy:
Exposure response prevention. Intensity of
symptoms and social disability reduced
21. Social Phobia
Inappropriate anxiety is experienced in situations in
which the person is observed and could be criticized
One year prevalence:
Male: 7%
Female: 9%
22. Clinical features
Avoid social situations
Avoid making conversations
Sit in least conspicuous places
Blushing and trembling frequent
Even thought of such situations anxiety
provoking
Preoccupied by ideas that will be observed
critically (but knows that this ideas are
baseless)
23. Clinical features
Onset : 17 – 30 yrs
Ist episode in public places without apparent
reason
Episodes gradually increase in severity and
later on associated with avoidance
Special mention:
Phobia of excretion
Phobia of vomiting
25. Differntial diagnosis
Avoidant personality disorder (no specific onset, lifelong
shyness)
Social inadequacy
Other anxiety disorders,depression and schizophrenia
26. Course and prognosis
Average 20 yrs duration
Persists inspite of treatment
DSH only if co-morbid depression and alcohol misuse
27. Treatment
Medications: Benzodiazepines (short term only),
beta blockers and antidepressants
CBT: most effective when combined with exposure
therapy. Also given in group format
Relaxation training: ineffective alone, but effective
when combined with exposure (applied relaxation)
Dynamic psychotherapy
28. Agoraphobia
Anxiety when patients are away from
home, in crowds or in situations that
they cannot leave easily
Life time prevalence: 6 to 10 %
29. Clinical features
Situational anxiety: Characterized by panic
attacks and anxious cognitions about
fainting and loss of control
Avoidance of situations which provoke
anxiety
3 common themes:
distance from home
crowding
confinement
30. Clinical features
Anxiety reduced if accompanied by
companion, pet dog or child
Anticipatory anxiety
Other symptoms: commonly
depressive, depersonalization and
obsessive thoughts
31. Onset and course
Early or middle 20’s
First episode typically while waiting for
public transport or shopping
Extreme anxiety (with palpitations and
fainting) with quick recovery on
reaching home or hospital
As condition progresses – increased
dependance on spouse or others
33. Panic disorder
Sudden attacks of anxiety in which
physical symptoms predominate and
are accompanied by fear of a serious
consequence such as heart attack
Life time prevalence : 5.6%
34. Clinical features
Autonomic arousal
Somatic symptoms of anxiety
Psychological arousal
Fear of dying or going crazy
38. Aetiology
Genetic: 5 to 7 % of parents of patients have
OC symptoms
Evidence of a brain disorder (associated with
other neurological disorders and as suggested
by brain imaging studies)
Abnormal serotonergic function
39. Aetiology
Early experience: imitative learning
(unproven)
Psychoanalytical theories: repression and
reaction formation
Learning theory: rituals are equivalent to
avoidance responses
Cognitive theory: intrusive thoughts are
normal but patient lacks ability to control
them
42. Clinical features
Obsessional impulses:
Urges to perform acts of violent or
embarrassing kind
Obsessional slowness:
Slowness out of proportion to other
symptoms
43. Clinical features
Obsessional rituals:
Include mental activity like counting and
repeated senseless behaviours
Preceded by explanatory obsessional
thoughts
Rituals are illogical and there are attempts
to avoid
44. Clinical features
Obsessional Phobias:
Avoidance of certain situations
Anxiety: rituals either lessen or increase the
anxiety
Depression: reactive or co-existing
endogenous
45. Prognosis
2/3 rd improve partially by one year
Good prognostic indicators:
Precipitating event
Good social and occupational adjustment
Episodic symptoms
Shorter duration
Onset in adulthood
Stable pre morbid personality
47. Treatment
CBT:
Response prevention combined with
exposure to environmental cues
2/3rd of patients improve substantially
Cognitive therapy:
Techniques of suppression and distraction
May be combined with exposure
48. Treatment
Dynamic psychotherapy
Not effective
Neurosurgery:
Good immediate results
long term effects uncertain
Only for most chronic cass who resist
treatment for atleast one year