This document discusses signs, symptoms, diagnostic tests, severity scoring, and treatment strategies for pancreatitis. It provides sensitivity and specificity data for diagnostic tests like amylase, lipase, ultrasound, MRI, and CT scans. It also outlines a CT severity index scoring system for grading pancreatitis severity. Finally, it lists the key treatment aspects of pancreatitis management as fluids, pain control, antibiotics, nutrition, DVT prophylaxis, and potential interventions.

4. 90% 10%
Epigastic
Pain

5. 90% 10%
Nausea
And
Vomiting

6. 50%
50%
Pain
Radiating
To
Back

9. 3%97%
Cullen’s
Sign

10. 3%97%
Grey
Turner
Sign

14. Amylase
Sensitivity
67-83%

15. Amylase
Specificity
85-98%

17. Lipase
Sensitivity
82-100%

18. Lipase
Specificity
82-100%

21. Ultrasound
Nondiagnostic
25-35%

23. MRI
Sensitivity
83%

24. MRI
Specificity
91%

26. CT
Sensitivity
78%

27. CT
Specificity
86%

28. Grade Findings Score
A Normal pancreas 0
B Focal or diffuse enlargement
without inflammation
1
C Peripancreatic inflammation 2
D Intrapancreatic or
extrapancreatic fluid collections
4
E Gas collections 4
Percent Necrosis Score
0% 0
Less than 33% 2
33-50% 4
50% or more 6
CTSI = Grade Score + Necrosis Score
CTSI of 6 or more is severe pancreatitis

31. Pancreatitis
Fluids
Pain Control
Antibiotics
Nutrition
DVT
Prophylaxis
Intervention

32. Pancreatitis
Fluids

33. Pancreatitis
Fluids
Vital Signs
Hematocrit
Renal Function

34. Pancreatitis
Pain
Control

35. Pancreatitis
Antibiotics

36. Pancreatitis
Antibiotics
Difficult evaluate sepsis
Infected necrosis
- Culture (IR)
- Antibiotics

37. Pancreatitis

38. Pancreatitis
Nutrition
Oral
Enteral
Parenteral (TPN)

39. Pancreatitis
Nutrition
Early enteral
nutrition reduces
mortality

40. Pancreatitis
DVT
Prophylaxis

41. Pancreatitis
DVT
Prophylaxis
High risk of DVT
Splanchnic thrombosis
- 1-24%

42. Pancreatitis
Aspiration/Drainage
Focused on underlying
cause
Interventio
n

43. Pancreatitis
Fluids
Pain Control
Antibiotics
Nutrition
DVT
Prophylaxis
Intervention