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Transforming Healthcare: The Quantification of Everything
- 1. TRANSFORMING HEALTHCARE THE QUANTIFICATION OF EVERYTHING STEVEN TUCKER, MD, FACP, FAMS Global Health Advisor, SingTel Founder, Tucker Medical
- 2. WARNING ! We tend to overestimate the effect of a technology in the short run and underestimate the effect in the long run. Roy Amara Co-founder, Institute for the Future
- 4. 1974 1984 1994 2004 2014 EXPONENTIALS 4E+09 3E+09 2E+09 1E+09 4E+03
- 5. 4E+09 3E+09 2E+09 1E+09 4E+03 COMPUTING POWER 1974 1984 1994 2004 2014 2024
- 6. 4E+09 3E+09 2E+09 1E+09 4E+03 MOORE’S LAW 1974 1984 1994 2004 2014 2024
- 7. Computers 4E+09 3E+09 2E+09 1E+09 4E+03 MOORE’S LAW 1974 1984 1994 2004 2014 2024
- 8. Computers 4E+09 3E+09 Sensors 2E+09 1E+09 4E+03 MOORE’S LAW 1974 1984 1994 2004 2014 2024
- 9. Computers 4E+09 3E+09 Sensors 2E+09 1E+09 4E+03 MOORE’S LAW Biology 1974 1984 1994 2004 2014 2024
- 10. Computers 4E+09 3E+09 Sensors 2E+09 1E+09 4E+03 MOORE’S LAW Biology Pan-omics 1974 1984 1994 2004 2014 2024
- 11. 2 PROBLEMS
- 12. Healthcare is not a science problem, it’s an information problem. -Thomas Goetz
- 13. DIABETES 382 Million Source: International Diabetes Federation
- 14. OBESITY 500 Million Source: World Health Organisation
- 15. HEART DISEASE 17.3 Million Source: World Health Organisation
- 16. CANCER 14.1 Million Source: World Health Organisation
- 17. 3 SENSORS
- 18. If you cannot measure it, you cannot improve it. -Lord Kelvin
- 19. SENSOR EVOLUTION Sensor 1.0 Sensor 2.0 Sensor 3.0 Ability to measure + record signal Sensor web integration; share + access data Passive data gathering + aggregating + meaningful insight
- 20. ACTIVITY
- 21. HEALTH
- 22. MEDICAL
- 23. THE TRICORDER
- 24. VITAL SIGNS
- 25. EMERGENCY
- 41. BIRTH CONTROL
- 43. 4 BIOLOGY
- 46. THERANOS
- 47. RETAIL LABS
- 48. HOME TRACKING
- 49. HOME DIAGNOSIS
- 50. HOME DIAGNOSIS
- 51. LAB ON A CHIP
- 52. CELL CAPTURE
- 53. LIQUID BIOPSY
- 55. GENOME MATH 23Pairs of chromosomes
- 56. GENOME MATH 20k Genes
- 57. GENOME MATH 4Bases A - T G - C
- 58. GENOME MATH 3.2 Base pairs per genome billion
- 59. GENOME MATH 3.2billion 40xCoverage BP 128billion data points
- 60. SEQUENCING $
- 61. GENOMICS 2001
- 62. GENOMICS 2007
- 63. GENOMICS 2013
- 64. GENOMICS 2014
- 65. GENOMICS 2014
- 66. GENOMICS 2016
- 67. GENOMICS 2018
- 70. NEXT NEXT GEN SEQUENCING ?
- 73. 5 PLATFORMS
- 75. $2.4 Billion
- 76. $26 Billion
- 77. SENSORS
- 79. SENSORS Gyroscope Proximity Gesture Fingerprint
- 80. SENSORS Gyroscope Proximity Gesture Compass Fingerprint Hall cover
- 81. SENSORS Gyroscope Gesture Heart rate Proximity Compass Barometer Fingerprint Hall cover
- 82. SENSORS Gyroscope Gesture Ambient light Heart rate Accelerometer Proximity Compass Barometer Fingerprint Hall cover
- 86. 6 PAN-OMICS
- 91. Exposome 33 48 Cd 80 Hg 28 Ni 81 82 Ti Pb As
- 92. EPphigeennoommee
- 93. ! TRANSFORM
- 94. Digital Health as Google Map HEALTH AS A GOOGLE MAP SENSOR ACTIVITY DIET GENOME MICROBIOME LAB PHENOME UNIQUE PERSON
- 95. Digital Health as Google Map HEALTH AS A GOOGLE MAP SENSOR ACTIVITY DIET GENOME MICROBIOME LAB PHENOME UNIQUE PERSON
- 96. 6P4 MEDICINE
- 97. P4 MEDICINE 1. Predictive 2. Preventive 3. Personalized 4. Participatory
- 98. 100k WELLNESS PROJECT 1. Predictive 2. Preventive 3. Personalized 4. Participatory
- 99. P4 MEDICINE Predictive You will track your health. It’s your data. Identify transition states.
- 100. P4 MEDICINE Preventive Wellness networks. Illness networks. A systems-based approach to repair and maintenance.
- 101. P4 MEDICINE Personalized You are your own control. Your health data cloud. Molecular + Environmental.
- 102. P4 MEDICINE Participatory Transformative for health. Societal change - enormous. Patients will adapt. Doctors may adapt?
- 103. THE PIVOT Health Status 20% of patients = 80% of costs Healthy Low Risk At Risk High Risk Chronic Disease Early Active Disease End of Life Care Chronic Disease Progression VALUE COST
- 104. 6 LONGEVITY
- 106. Life Expectancy at birth 85 82 79 76 73 70 1990 2000 2008 1990 2000 2008 1990 2000 2008 1990 2000 2008 < 12 12 13-‐15 > 16 Years of Educa>on
- 107. TECHNOLOGY
- 108. BIOLOGY
- 110. CALICO
- 111. 7 AND…
- 120. THANK YOU For your 9me & a>en9on