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Passive Home-based
Monitoring in an Era of
Telemedicine


Robin A. Felder, Ph.D.
The University of Virginia
Professor of Pathology
Associate Director Clinical
Chemistry


http://medicalautomation.org




 Wellness

   State of complete
    physical, mental and
    social well-being
   Health results from
    primarily positive
    perspectives and choices
                                   Physical                 Social
    by hi h to live
    b which t li
                                              6.2     9.1
   Technology can provide                          8.0
    information that facilitates               Cognitive 
    positive choices
                                                              © Felder, 2011




                                                                                      





Wellness

 Feeling well
 Achieving wellness
 Wellness strategies
 Denial or retraining




Wellness Support
 Growing need for new
  sources of data, and data
                 ,
  interpretation
 Integration of multiple
  diagnostic sources (clinical,
  radiology, molecular
  biology, pharmacy, lifestyle)
 Integrated wellness and
  health record
 Ongoing information
  support for maintaining
  healthy lifestyles




                                         





Wellness Support

 Food coaching
              g
 Exercise rewards
 Consequence
  reporting
 Consequence
  forecasting                   Overcome vicarious
                                goal fulfillment or,
                                “exhaustion of self-
                                control”




Home Health IT
                                 Cloud  
 Integration of multiple   Interpretations

  information sources
  (wellness,
  socialization, medical)
 New revenue source:
  Medical Cloud
  coaching and
       hi      d
  Interpretations




                                                              





AN EXAMPLE



SALT, THE #1 
KILLER


                             Vogue   4‐10




Example of Medical Cloud 
Interpretation
 Hypogen-DX
  (Hypertension/Salt
  Sensitivity Genomic
  Interpretation)
 3 SNP test ($300)
   Proprietary algorithms
   Determines probability
    of developing HT or
    SS
   1st Example of
    Molecular Diagnostics
    for Chronic Disease




                                                   





Wellness Technologies       Cognitive           Social
                                     6.2 9.1
 Nutrition                               8.0
                                         Physical
 Exercise
 Biometrics
 Stress reduction
 Mood enhancement
 Pain reduction
 Sleep improvement
 Health and wellness monitoring




New Communication Paradigms




                                                                





Embedded Wellness Sensors
   Instrument common
    fixtures
   Wireless
    transmission of data
   Web based
    aggregation and
    interpretation




Action Inspired Instruction

 Real time coaching
 Medically approved
  content
 Tailored for the
  individual




                                     





             Passive Wellness Monitoring



Healthcare providers




                                                     Vital Sensor

                                                 ·Body temperature
                                                 ·Pulse
                                Urine analyzer   ·Blood Pressure
                                                 ·Body fat percentage
                                 Urine protein
 Data management PC              Urine glucose




The M.A.R.C. In-Home
Health Monitoring Project

      C
       Create a model where the impact of chronic  
                 d l  h   h  i          f  h i
       disease is delayed or avoided
      Provide opportunity for medical intervention 
       before a crisis occurs
      Minimize impact of chronic disease on the 
       healthcare system
      Potentially delay admittance to a nursing home 
       and reduce the cost of healthcare




                                                                               





  Passive Wireless 
  Sensor Systems




 WellAWARE™, provides unobtrusive, highly
  accurate wellness monitoring services to allow
  individuals to age with options.
                                                                        15




 Passive Remote Sensing
 The WellAWARE™ solution has three primary
  elements that work together to provide passive, yet
  informative, monitoring of seniors:
     Wireless Sensor Array (WSA) – gathers data on daily activities
     Data Manager (DM) –transmits data to data analysis servers
     Capture Analysis & Reporting Engine (CARE) – captures potential
      problems and alerts caregiver




                                                                                    





Sleep Monitoring
 Sleep apnea affects more
  than 40 million people in the
  United States alone of which
  85% are currently
  undiagnosed
 sleep apnea testing and
  therapy market that is
  expected to reach more that
  $4 billion by 2012




     Passive Vital Sign Bed Monitor
                                        Polysomnography
Mattress pad to measure:
• Sleep quality
• Pulse (and HRV)
• Breathing
• Movement/
  restlessness
• Bed exit
• Subject position/
  turning
• Body temperature
• Blood Pressure
                      Passive Sensing




                                                                 





            Sleep Quality Graphs

                              Restful Resident




Restless Resident




  Remote Automated Triage

   Real time assessment of participant health
    status/well being
   Ability to drill down to specifics
   Built in automated optimized dispatching
   Manual override of dispatch event or
    downstream processes




                                                       





                        21




   One Click Trending


 Health
 Socialization
 System 
  utilization




                                   





Telehome Monitoring Decreases
Costs by 74%
                                 Overall Cost of Care Comparison
            80000

            70000
                             $67,757.88
            60000



                                   onitored
            50000
Dollars $




            40000               Unmo
            30000

            20000
                                                      $17,407.02
            10000                                     Monitored
                0

                    N=21 in each group, P<0.05;
                    Telemed J E Health, 




                       FUTURE WELLNESS 
                       TECHNOLOGIES




                                                                         





                            




Underwear That Measures Blood 
Pressure
 Pulse wave velocity
  correlates with blood
  pressure
 Tissue impedance shows
  passing pulses
 Pulse timing correlated
  with relative pressure
 Continuous blood
  pressure monitoring




                                       





    Automated Pharmaceuticals
 Automated Pill – iPill (Philips)
 Magnatrace™ System looks for p
      g        y               pill
  ingestion
 Networked pills (Proteus
  Biomedical)
   Instrumented Pills
   Cost < $0.01
   Measure and send physiologic signals
    through body electrically
   Receiver is a patch worn on the body
    that also logs respiration, heart rate and
    body movement, sleep patterns




 Automated Intestinal Biopsies

                                   Intestinal diagnostic
                                    imaging coupled with
                                    miniaturized biopsies
                                   Pillcams with
                                    intestinal “Velcro” to
                                    arrest the camera at
                                    a selective l
                                         l ti location
                                                     ti
                                   Continuous
                                    monitoring

       MIT Technology Lab




                                                                   





The Eye as the Window to Health




   UCSC




               Univ. of MD, Baltimore

                       Medical Robotics




 Medical Robotics, LLC

   Real time glucose
    monitoring
   Alerts for low or high
    glucose concentrations
   Trending analysis
   Food coaching via
    telenutritionalmentoring




                                                





Receptivity

  Presenting health vs
   wellness to a patient
  Determining what
   information is TMI
  Optimizing the time
   for the presentation
   of wellness strategies
   “Wellformation”




Augmented Reality

 Projection of
  underlying anatomy
    d l i          t
  on living tissue
 Relies on
  superimposition of
  reality and
  previously scanned
  animated image/data




                                  





Not for the Faint Hearted




Robotic Reality




  HRP‐4C National Institute of 
  Advanced Industrial Science and 
  Technology




                                           





      





      





  The Wellness Health Paradigm 


                                    Evaluation
       Predictive      Continuous
                                    and
       Diagnostics     Monitoring
                                    Reporting




                                                            




    Medical Automation.org

A non-profit
educational
organization
improving
healthcare quality
and efficiency
through teaching
automation
principles and
their application in         http://medicalautomation.org
health systems




                                                                       





  TagLine ‐ Medical reality
http://medicalautomation.org




                                     

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Passive Home-based Monitoring in an Era of Telemedicine

  • 1.  Passive Home-based Monitoring in an Era of Telemedicine Robin A. Felder, Ph.D. The University of Virginia Professor of Pathology Associate Director Clinical Chemistry http://medicalautomation.org Wellness  State of complete physical, mental and social well-being  Health results from primarily positive perspectives and choices Physical Social by hi h to live b which t li 6.2 9.1  Technology can provide 8.0 information that facilitates Cognitive  positive choices © Felder, 2011 
  • 2.  Wellness  Feeling well  Achieving wellness  Wellness strategies  Denial or retraining Wellness Support  Growing need for new sources of data, and data , interpretation  Integration of multiple diagnostic sources (clinical, radiology, molecular biology, pharmacy, lifestyle)  Integrated wellness and health record  Ongoing information support for maintaining healthy lifestyles 
  • 3.  Wellness Support  Food coaching g  Exercise rewards  Consequence reporting  Consequence forecasting Overcome vicarious goal fulfillment or, “exhaustion of self- control” Home Health IT Cloud    Integration of multiple Interpretations information sources (wellness, socialization, medical)  New revenue source: Medical Cloud coaching and hi d Interpretations 
  • 4.  AN EXAMPLE SALT, THE #1  KILLER Vogue   4‐10 Example of Medical Cloud  Interpretation  Hypogen-DX (Hypertension/Salt Sensitivity Genomic Interpretation)  3 SNP test ($300)  Proprietary algorithms  Determines probability of developing HT or SS  1st Example of Molecular Diagnostics for Chronic Disease 
  • 5.  Wellness Technologies Cognitive  Social 6.2 9.1  Nutrition 8.0 Physical  Exercise  Biometrics  Stress reduction  Mood enhancement  Pain reduction  Sleep improvement  Health and wellness monitoring New Communication Paradigms 
  • 6.  Embedded Wellness Sensors  Instrument common fixtures  Wireless transmission of data  Web based aggregation and interpretation Action Inspired Instruction  Real time coaching  Medically approved content  Tailored for the individual 
  • 7.  Passive Wellness Monitoring Healthcare providers Vital Sensor ·Body temperature ·Pulse Urine analyzer ·Blood Pressure ·Body fat percentage Urine protein Data management PC Urine glucose The M.A.R.C. In-Home Health Monitoring Project  C Create a model where the impact of chronic       d l  h   h  i   f  h i disease is delayed or avoided  Provide opportunity for medical intervention  before a crisis occurs  Minimize impact of chronic disease on the  healthcare system  Potentially delay admittance to a nursing home  and reduce the cost of healthcare 
  • 8.  Passive Wireless  Sensor Systems  WellAWARE™, provides unobtrusive, highly accurate wellness monitoring services to allow individuals to age with options. 15 Passive Remote Sensing  The WellAWARE™ solution has three primary elements that work together to provide passive, yet informative, monitoring of seniors:  Wireless Sensor Array (WSA) – gathers data on daily activities  Data Manager (DM) –transmits data to data analysis servers  Capture Analysis & Reporting Engine (CARE) – captures potential problems and alerts caregiver 
  • 9.  Sleep Monitoring  Sleep apnea affects more than 40 million people in the United States alone of which 85% are currently undiagnosed  sleep apnea testing and therapy market that is expected to reach more that $4 billion by 2012 Passive Vital Sign Bed Monitor Polysomnography Mattress pad to measure: • Sleep quality • Pulse (and HRV) • Breathing • Movement/ restlessness • Bed exit • Subject position/ turning • Body temperature • Blood Pressure Passive Sensing 
  • 10.  Sleep Quality Graphs Restful Resident Restless Resident Remote Automated Triage  Real time assessment of participant health status/well being  Ability to drill down to specifics  Built in automated optimized dispatching  Manual override of dispatch event or downstream processes 
  • 11.  21 One Click Trending  Health  Socialization  System  utilization 
  • 12.  Telehome Monitoring Decreases Costs by 74% Overall Cost of Care Comparison 80000 70000 $67,757.88 60000 onitored 50000 Dollars $ 40000 Unmo 30000 20000 $17,407.02 10000 Monitored 0 N=21 in each group, P<0.05; Telemed J E Health,  FUTURE WELLNESS  TECHNOLOGIES 
  • 13.   Underwear That Measures Blood  Pressure  Pulse wave velocity correlates with blood pressure  Tissue impedance shows passing pulses  Pulse timing correlated with relative pressure  Continuous blood pressure monitoring 
  • 14.  Automated Pharmaceuticals  Automated Pill – iPill (Philips)  Magnatrace™ System looks for p g y pill ingestion  Networked pills (Proteus Biomedical)  Instrumented Pills  Cost < $0.01  Measure and send physiologic signals through body electrically  Receiver is a patch worn on the body that also logs respiration, heart rate and body movement, sleep patterns Automated Intestinal Biopsies  Intestinal diagnostic imaging coupled with miniaturized biopsies  Pillcams with intestinal “Velcro” to arrest the camera at a selective l l ti location ti  Continuous monitoring MIT Technology Lab 
  • 15.  The Eye as the Window to Health UCSC Univ. of MD, Baltimore Medical Robotics Medical Robotics, LLC  Real time glucose monitoring  Alerts for low or high glucose concentrations  Trending analysis  Food coaching via telenutritionalmentoring 
  • 16.  Receptivity  Presenting health vs wellness to a patient  Determining what information is TMI  Optimizing the time for the presentation of wellness strategies “Wellformation” Augmented Reality  Projection of underlying anatomy d l i t on living tissue  Relies on superimposition of reality and previously scanned animated image/data 
  • 20.  The Wellness Health Paradigm  Evaluation Predictive Continuous and Diagnostics Monitoring Reporting  Medical Automation.org A non-profit educational organization improving healthcare quality and efficiency through teaching automation principles and their application in http://medicalautomation.org health systems 
  • 21.  TagLine ‐ Medical reality http://medicalautomation.org 