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How Open Scholarship is changing research 
William Gunn, Ph.D. Head of Academic Outreach Mendeley @mrgunn
How is Open Scholarship changing research? 
Like Open Source changed the world
How did Open Source change the world? 
It made software and hardware… 
•Better 
•Faster 
•Cheaper
What is Open Source? 
•Code that’s freely available 
•The product of an open, collaborative process. 
What is Open Scholarship? 
•Research that’s freely available. 
•The product of an open, collaborative process. 
Open to anyone, everyone is on the team.
Openness makes debugging easier 
Image via malcolmhq
Research is full of bugs 
•47 of 53 “landmark” oncology papers not reproduced (Amgen) 
•43 of 67 cardio/oncology papers contradictory (Bayer) 
•431 of 432 oncology publications not reproduced (Ioannidis)
We didn’t see that a target is more likely to be validated if it was reported in ten publications or in two publications 
NATURE REVIEWS DRUG DISCOVERY 10, 712 (SEPTEMBER 2011)
OA Week 2012 Miami U: How Open Scholarship is Changing Research
OA Week 2012 Miami U: How Open Scholarship is Changing Research
Either the results were reproducible and showed transferability in other models, or even a 1:1 reproduction of published experimental procedures revealed inconsistencies between published and in-house data 
NATURE REVIEWS DRUG DISCOVERY 10, 712 (SEPTEMBER 2011)
How does openness make research more efficient? 
Open Source 
•Microsoft 
•Reduced costs 
•More stakeholders 
•More public support 
•Lower barriers to entry 
Open Scholarship 
•Elsevier 
•More stakeholders 
•More public support 
•Decreasing costs 
•Barriers to entry still high 
P212121 Science Exchange 
#Rstats PeerJ eLife 
Mendeley
OA Week 2012 Miami U: How Open Scholarship is Changing Research
Sustainability of open projects 
Open Source 
•Professional services 
–Support 
–Consulting 
–Hosting 
•Advertising 
•Platform for services 
Open Scholarship 
•Professional services 
– core facilities 
–Science Exchange 
•Crowdfunding 
–Microryza 
–Petridish 
Grants do not provide long-term sustainability!
Sustainability 
•Leverage economies of scale 
•PubMed Central costs about $4M/year 
•Elsevier costs $2B, 38% is profit 
–and many of the costs are no longer necessary
“The most common barrier to accessing journal articles 
in both academia and industry is the requirement 
for researchers to pay for access. In a 2006 study, 35% of respondents reported difficulty getting access.” 
RIN, PRC and JISC report. Access to scholarly content: gaps and barriers (2011). 
http://rinarchive.jisc-collections.ac.uk/node/1172 
PRC. Journals and scientific productivity. A case study in immunologyand microbiology (2006). http://www.homepages.ucl.ac.uk/~uczciro/prcwhitepaper.pdf
OA Week 2012 Miami U: How Open Scholarship is Changing Research
OA Week 2012 Miami U: How Open Scholarship is Changing Research
The Cost of Knowledge 
13K signed
OA Week 2012 Miami U: How Open Scholarship is Changing Research
OA Week 2012 Miami U: How Open Scholarship is Changing Research
The future of research is in our hands 
•Most journals have an Open Access option 
–Pick a fully open journal, not a hybrid 
•Self-archiving is allowed for most works 
–Local repository or disciplinary(Arxiv, Pubmed Central, etc) 
•There are viable alternatives to the impact factor for research assessment 
–Article-level metrics such as readership, downloads, shares convey more dimensions of impact
Building an open community 
•Open Source isn’t just about source code 
–Usability, communications, marketing 
•Why would non-technical people care? 
–For fun, for experience, for their community 
•Communities are developing around diseases and problems 
–PatientsLikeMe
Companies are part of the community too. 
•Some of the best work in social science, political science, data science is done in industry. 
•Bridging the divide 
•Building tools to facilitate the process
When will this happen? 
http://roarmap.eprints.org/cgi/exportview/type/funder=5Fmandate/Graph/funder=5Fmandate.png
Open Access in Biomedical Research | September 2012 http://goo.gl/2eh32
20% of papers are open access 
Laakso and Björk BMC Medicine 2012,10:124 http://www.biomedcentral.com/1741-7015/10/124
www.mendeley.com

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OA Week 2012 Miami U: How Open Scholarship is Changing Research

  • 1. How Open Scholarship is changing research William Gunn, Ph.D. Head of Academic Outreach Mendeley @mrgunn
  • 2. How is Open Scholarship changing research? Like Open Source changed the world
  • 3. How did Open Source change the world? It made software and hardware… •Better •Faster •Cheaper
  • 4. What is Open Source? •Code that’s freely available •The product of an open, collaborative process. What is Open Scholarship? •Research that’s freely available. •The product of an open, collaborative process. Open to anyone, everyone is on the team.
  • 5. Openness makes debugging easier Image via malcolmhq
  • 6. Research is full of bugs •47 of 53 “landmark” oncology papers not reproduced (Amgen) •43 of 67 cardio/oncology papers contradictory (Bayer) •431 of 432 oncology publications not reproduced (Ioannidis)
  • 7. We didn’t see that a target is more likely to be validated if it was reported in ten publications or in two publications NATURE REVIEWS DRUG DISCOVERY 10, 712 (SEPTEMBER 2011)
  • 10. Either the results were reproducible and showed transferability in other models, or even a 1:1 reproduction of published experimental procedures revealed inconsistencies between published and in-house data NATURE REVIEWS DRUG DISCOVERY 10, 712 (SEPTEMBER 2011)
  • 11. How does openness make research more efficient? Open Source •Microsoft •Reduced costs •More stakeholders •More public support •Lower barriers to entry Open Scholarship •Elsevier •More stakeholders •More public support •Decreasing costs •Barriers to entry still high P212121 Science Exchange #Rstats PeerJ eLife Mendeley
  • 13. Sustainability of open projects Open Source •Professional services –Support –Consulting –Hosting •Advertising •Platform for services Open Scholarship •Professional services – core facilities –Science Exchange •Crowdfunding –Microryza –Petridish Grants do not provide long-term sustainability!
  • 14. Sustainability •Leverage economies of scale •PubMed Central costs about $4M/year •Elsevier costs $2B, 38% is profit –and many of the costs are no longer necessary
  • 15. “The most common barrier to accessing journal articles in both academia and industry is the requirement for researchers to pay for access. In a 2006 study, 35% of respondents reported difficulty getting access.” RIN, PRC and JISC report. Access to scholarly content: gaps and barriers (2011). http://rinarchive.jisc-collections.ac.uk/node/1172 PRC. Journals and scientific productivity. A case study in immunologyand microbiology (2006). http://www.homepages.ucl.ac.uk/~uczciro/prcwhitepaper.pdf
  • 18. The Cost of Knowledge 13K signed
  • 21. The future of research is in our hands •Most journals have an Open Access option –Pick a fully open journal, not a hybrid •Self-archiving is allowed for most works –Local repository or disciplinary(Arxiv, Pubmed Central, etc) •There are viable alternatives to the impact factor for research assessment –Article-level metrics such as readership, downloads, shares convey more dimensions of impact
  • 22. Building an open community •Open Source isn’t just about source code –Usability, communications, marketing •Why would non-technical people care? –For fun, for experience, for their community •Communities are developing around diseases and problems –PatientsLikeMe
  • 23. Companies are part of the community too. •Some of the best work in social science, political science, data science is done in industry. •Bridging the divide •Building tools to facilitate the process
  • 24. When will this happen? http://roarmap.eprints.org/cgi/exportview/type/funder=5Fmandate/Graph/funder=5Fmandate.png
  • 25. Open Access in Biomedical Research | September 2012 http://goo.gl/2eh32
  • 26. 20% of papers are open access Laakso and Björk BMC Medicine 2012,10:124 http://www.biomedcentral.com/1741-7015/10/124